GRK2 (NM_001619) Human Tagged ORF Clone

CAT#: RC210327L1

  • LentiORF®

Lenti ORF clone of Human adrenergic, beta, receptor kinase 1 (ADRBK1) , Myc-DDK-tagged

  View "NM_001619" in other vectors (10)

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USD 790.00


Availability*
In Stock

Size
    • 10 ug


Product images

Specifications

Product Data
Product Name GRK2 (NM_001619) Human Tagged ORF Clone
Symbol GRK2
Synonyms ADRBK1; BARK1; BETA-ARK1
Vector pLenti-C-Myc-DDK
Sequence Data
The ORF insert of this clone is exactly the same as(RC210327).
Restriction Sites SgfI-RsrII      Cloning Scheme for this gene     
Tag Myc-DDK
ACCN NM_001619
ORF Size 2076 bp
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Product Components The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Reference Data
RefSeq NM_001619.2, NP_001610
RefSeq Size 3603
RefSeq ORF 2070
Locus ID 156
Cytogenetics 11q13.2
Domains RGS, pkinase, S_TK_X, TyrKc, PH, S_TKc
Protein Families Protein Kinase, Druggable Genome
Protein Pathways Chemokine signaling pathway, Endocytosis
MW 79.4 kDa
Gene Summary The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart. [provided by RefSeq, Jul 2008].

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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