CD26 (DPP4) (NM_001935) Human Tagged ORF Clone
Lenti ORF clone of Human dipeptidyl-peptidase 4 (DPP4), mGFP tagged
|Product Name||CD26 (DPP4) (NM_001935) Human Tagged ORF Clone|
|Type||Human Tagged ORF Clone|
|Synonyms||ADABP; ADCP2; CD26; DPPIV; TP103|
|E. coli Selection||Chloramphenicol (34 ug/mL)|
|Restriction Sites||SgfI-MluI Cloning Scheme for this gene|
|ORF Size||2298 bp|
|OTI Disclaimer||The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info|
|OTI Annotation||This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.|
|Product Components||The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.|
|Reconstitution||1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
|RefSeq Size||3913 bp|
|RefSeq ORF||2301 bp|
|Protein Families||Druggable Genome, Protease, Secreted Protein, Transmembrane|
|Gene Summary||The DPP4 gene encodes dipeptidyl peptidase 4, which is identical to adenosine deaminase complexing protein-2, and to the T-cell activation antigen CD26. It is an intrinsic type II transmembrane glycoprotein and a serine exopeptidase that cleaves X-proline dipeptides from the N-terminus of polypeptides. Dipeptidyl peptidase 4 is highly involved in glucose and insulin metabolism, as well as in immune regulation. This protein was shown to be a functional receptor for Middle East respiratory syndrome coronavirus (MERS-CoV), and protein modeling suggests that it may play a similar role with SARS-CoV-2, the virus responsible for COVID-19. [provided by RefSeq, Apr 2020]|
|cDNA Clone Resources|
|RC209466L1||Lenti ORF clone of Human dipeptidyl-peptidase 4 (DPP4), Myc-DDK-tagged||
|RC209466L4||Lenti ORF clone of Human dipeptidyl-peptidase 4 (DPP4), mGFP tagged||
|RC209466L3||Lenti ORF clone of Human dipeptidyl-peptidase 4 (DPP4), Myc-DDK-tagged||
|RG209466||DPP4 (GFP-tagged) - Human dipeptidyl-peptidase 4 (DPP4)||
|SC118956||DPP4 (untagged)-Human dipeptidyl-peptidase 4 (DPP4)||
|RC209466||DPP4 (Myc-DDK-tagged)-Human dipeptidyl-peptidase 4 (DPP4)||