ADAMTS4 (NM_005099) Human Tagged ORF Clone

CAT#: RC209226L4

  • LentiORF®

Lenti ORF clone of Human ADAM metallopeptidase with thrombospondin type 1 motif, 4 (ADAMTS4), mGFP tagged

  View "NM_005099" in other vectors (10)

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USD 860.00


Availability*
3 Weeks

Size
    • 10 ug


Product images

Specifications

Product Data
Product Name ADAMTS4 (NM_005099) Human Tagged ORF Clone
Symbol ADAMTS4
Synonyms ADAMTS-2; ADAMTS-4; ADMP-1
Vector pLenti-C-mGFP-P2A-Puro
Sequence Data
The ORF insert of this clone is exactly the same as(RC209226).
Restriction Sites SgfI-MluI      Cloning Scheme for this gene     
Tag mGFP
ACCN NM_005099
ORF Size 2511 bp
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Product Components The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Reference Data
RefSeq NM_005099.3, NP_005090
RefSeq Size 4342
RefSeq ORF 2514
Locus ID 9507
Cytogenetics 1q23.3
Protein Families Secreted Protein, Transmembrane, Protease, Druggable Genome
MW 90 kDa
Gene Summary Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover. May play an important role in the destruction of aggrecan in arthritic diseases. Could also be a critical factor in the exacerbation of neurodegeneration in Alzheimer disease. Cleaves aggrecan at the '392-Glu-|-Ala-393' site. [UniProtKB/Swiss-Prot Function]

Other Versions

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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