UGT(UGT1A9) (NM_021027) Human Tagged ORF Clone
UGT1A9 (Myc-DDK-tagged)-Human UDP glucuronosyltransferase 1 family, polypeptide A9 (UGT1A9)Change vector?
|Product Name||UGT(UGT1A9) (NM_021027) Human Tagged ORF Clone|
|Synonyms||HLUGP4; LUGP4; UDPGT; UDPGT 1-9; UGT-1I; UGT1-09; UGT1-9; UGT1.9; UGT1A9S; UGT1AI; UGT1I|
ORF Nucleotide Sequence
>RC208861 representing NM_021027
Red=Cloning site Blue=ORF Green=Tags(s)
>RC208861 representing NM_021027
Red=Cloning site Green=Tags(s)
Sequencher program is needed, download here.
|Restriction Sites||SgfI-MluI Cloning Scheme for this gene Plasmid Map|
|ORF Size||1590 bp|
|OTI Disclaimer||Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at email@example.com or by calling 301.340.3188 option 3 for pricing and delivery.
The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
|OTI Annotation||This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.|
|Product Components||The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.|
|RefSeq||NM_021027.1, NM_021027.2, NP_066307|
|Protein Families||Transmembrane, Druggable Genome|
|Protein Pathways||Pentose and glucuronate interconversions, Ascorbate and aldarate metabolism, Androgen and estrogen metabolism, Starch and sucrose metabolism, Retinol metabolism, Porphyrin and chlorophyll metabolism, Metabolism of xenobiotics by cytochrome P450, Drug metabolism - cytochrome P450, Drug metabolism - other enzymes, Metabolic pathways|
|Gene Summary||This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene is active on phenols. [provided by RefSeq, Jul 2008].|
|The use of this cDNA Clones has been cited in the following citations:|
Detoxification: A Novel Function of BRCA1 in Tumor Suppression?
,Hyo Jin Kang, Young Bin Hong, Hee Jeong Kim, Olga C. Rodriguez, Raghu G. Nath, Elena M. Tilli, Christopher Albanese, Fung-Lung Chung, Sang Hoon Kwon, and Insoo Bae,
Toxicol. Sci., Jul 2011; 122: 26 - 37.
|cDNA Clone Resources|
"UGT1A9" in other Product Lines