CD163 (NM_004244) Human Tagged ORF Clone

CAT#: RC208557L4

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  • LentiORF®

Lenti ORF clone of Human CD163 molecule (CD163), transcript variant 1, mGFP tagged

  View "NM_004244" in other vectors (10)

USD 1,150.00


Availability*
3 Weeks

Size
    • 10 ug


Product images

Specifications

Product Data
Product Name CD163 (NM_004244) Human Tagged ORF Clone
Symbol CD163
Synonyms M130; MM130; SCARI1
Vector pLenti-C-mGFP-P2A-Puro
E. coli Selection Chloramphenicol (34 ug/mL)
Cell Selection Puromycin
Sequence Data
The ORF insert of this clone is exactly the same as(RC208557).
Restriction Sites SgfI-RsrII      Cloning Scheme for this gene     
Tag mGFP
ACCN NM_004244
ORF Size 3468 bp
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Product Components The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Reference Data
RefSeq NM_004244.3, NP_004235
RefSeq Size 4190
RefSeq ORF 3471
Locus ID 9332
Cytogenetics 12p13.31
Domains SR
Protein Families Druggable Genome, Secreted Protein, Transmembrane
MW 125.4 kDa
Gene Summary The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]

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