Activin A Receptor Type IB (ACVR1B) (NM_004302) Human Tagged Lenti ORF Clone

  • LentiORF®
SKU
RC206920L2
Lenti ORF clone of Human activin A receptor, type IB (ACVR1B), transcript variant 1, mGFP tagged
  $770.00
3 Weeks*
Specifications
Specifications
Product Data
Type Human Tagged ORF Clone
Target Symbol Activin A Receptor Type IB
Synonyms ACTRIB; ACVRLK4; ALK4; SKR2
Vector pLenti-C-mGFP
E. coli Selection Chloramphenicol (34 ug/mL)
Mammalian Cell Selection None
Sequence Data
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(RC206920).
Restriction Sites SgfI-MluI Cloning Scheme for this gene | Plasmid Map
ACCN NM_004302
ORF Size 1515 bp
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_004302.3
RefSeq Size 4540 bp
RefSeq ORF 1518 bp
Locus ID 91
UniProt ID P36896
Cytogenetics 12q13.13
Domains Activin_recp, GS, pkinase, S_TKc, TyrKc
Protein Families Druggable Genome, Protein Kinase, Transmembrane
Protein Pathways Adherens junction, Chronic myeloid leukemia, Colorectal cancer, Cytokine-cytokine receptor interaction, Endocytosis, MAPK signaling pathway, Pancreatic cancer, Pathways in cancer, TGF-beta signaling pathway
MW 56.81 kDa
Summary This gene encodes an activin A type IB receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I and two type II receptors. This protein is a type I receptor which is essential for signaling. Mutations in this gene are associated with pituitary tumors. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Jun 2010]
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Documents
Resources
"NM_004302" in other vectors (7)
SKU Description Size Price
RC206920 ACVR1B (Myc-DDK-tagged)-Human activin A receptor, type IB (ACVR1B), transcript variant 1 10 ug
$470.00
RC206920L1 Lenti ORF clone of Human activin A receptor, type IB (ACVR1B), transcript variant 1, Myc-DDK-tagged 10 ug
$770.00
RC206920L3 Lenti ORF clone of Human activin A receptor, type IB (ACVR1B), transcript variant 1, Myc-DDK-tagged 10 ug
$770.00
RC206920L4 Lenti ORF clone of Human activin A receptor, type IB (ACVR1B), transcript variant 1, mGFP tagged 10 ug
$770.00
RG206920 ACVR1B (tGFP-tagged) - Human activin A receptor, type IB (ACVR1B), transcript variant 1 10 ug
$489.00 $670.00
SC108895 ACVR1B (untagged)-Human activin A receptor, type IB (ACVR1B), transcript variant 1 10 ug
$471.00
SC323520 ACVR1B (untagged)-Kinase deficient mutant (K234M) of Human activin A receptor, type IB (ACVR1B), transcript variant 1 10 ug
$471.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.