AXL (NM_021913) Human Tagged ORF Clone

CAT#: RC206431L2

Lenti ORF clone of Human AXL receptor tyrosine kinase (AXL), transcript variant 1, mGFP tagged

  • LentiORF®

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USD 835.00


Availability*
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Size
    • 10 ug

Cited in 2 publications.

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Specifications

Product Data
Product Name AXL (NM_021913) Human Tagged ORF Clone
Symbol AXL
Synonyms ARK; JTK11; Tyro7; UFO
Vector pLenti-C-mGFP
Sequence Data
The ORF insert of this clone is exactly the same as(RC206431).
Restriction Sites SgfI-MluI      Cloning Scheme for this gene     
Tag mGFP
ACCN NM_021913
ORF Size 2682 bp
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Product Components The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Reference Data
RefSeq NM_021913.2, NP_068713
RefSeq Size 5014
RefSeq ORF 2685
Locus ID 558
Cytogenetics 19q13.2
Protein Families Protein Kinase, Transmembrane, Druggable Genome
MW 98.2 kDa
Gene Summary The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). This gene may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Citations (2)