ELL2 (NM_012081) Human Tagged Lenti ORF Clone
CAT#: RC206204L2
- LentiORF®
Lenti ORF clone of Human elongation factor, RNA polymerase II, 2 (ELL2), mGFP tagged
"NM_012081" in other vectors (6)
Product Images
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | mGFP |
Symbol | ELL2 |
Synonyms | MRCCAT1 |
Vector | pLenti-C-mGFP |
E. coli Selection | Chloramphenicol (34 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC206204).
|
Restriction Sites | SgfI-MluI Cloning Scheme for this gene |
ACCN | NM_012081 |
ORF Size | 1920 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_012081.3 |
RefSeq Size | 6063 bp |
RefSeq ORF | 1923 bp |
Locus ID | 22936 |
UniProt ID | O00472 |
Cytogenetics | 5q15 |
Protein Families | Transcription Factors |
MW | 72.4 kDa |
Gene Summary | Elongation factor component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III (PubMed:22195968). Plays a role in immunoglobulin secretion in plasma cells: directs efficient alternative mRNA processing, influencing both proximal poly(A) site choice and exon skipping, as well as immunoglobulin heavy chain (IgH) alternative processing. Probably acts by regulating histone modifications accompanying transition from membrane-specific to secretory IgH mRNA expression.[UniProtKB/Swiss-Prot Function] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC206204 | ELL2 (Myc-DDK-tagged)-Human elongation factor, RNA polymerase II, 2 (ELL2) |
USD 596.00 |
|
RC206204L1 | Lenti ORF clone of Human elongation factor, RNA polymerase II, 2 (ELL2), Myc-DDK-tagged |
USD 896.00 |
|
RC206204L3 | Lenti ORF clone of Human elongation factor, RNA polymerase II, 2 (ELL2), Myc-DDK-tagged |
USD 896.00 |
|
RC206204L4 | Lenti ORF clone of Human elongation factor, RNA polymerase II, 2 (ELL2), mGFP tagged |
USD 896.00 |
|
RG206204 | ELL2 (tGFP-tagged) - Human elongation factor, RNA polymerase II, 2 (ELL2) |
USD 796.00 |
|
SC115584 | ELL2 (untagged)-Human elongation factor, RNA polymerase II, 2 (ELL2) |
USD 597.00 |
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