APPL(APPL1) (NM_012096) Human Tagged ORF Clone

CAT#: RC206021L1

  • LentiORF®

Lenti ORF clone of Human adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 (APPL1) , Myc-DDK-tagged

  View "NM_012096" in other vectors (10)

USD 790.00


Availability*
In Stock

Size
    • 10 ug


Product images

Specifications

Product Data
Product Name APPL(APPL1) (NM_012096) Human Tagged ORF Clone
Symbol APPL1
Synonyms APPL; DIP13alpha; MODY14
Vector pLenti-C-Myc-DDK
Sequence Data
The ORF insert of this clone is exactly the same as(RC206021).
Restriction Sites SgfI-MluI      Cloning Scheme for this gene     
Tag Myc-DDK
ACCN NM_012096
ORF Size 2127 bp
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Product Components The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Reference Data
RefSeq NM_012096.2, NP_036228
RefSeq Size 6061
RefSeq ORF 2130
Locus ID 26060
Cytogenetics 3p14.3
Domains PH, PID
Protein Pathways Pathways in cancer, Colorectal cancer
MW 79.5 kDa
Gene Summary The protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus. [provided by RefSeq, Jul 2008].

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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