FRS2 (NM_006654) Human Tagged ORF Clone

CAT#: RC205842L2

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  • LentiORF®

Lenti ORF clone of Human fibroblast growth factor receptor substrate 2 (FRS2), transcript variant 1, mGFP tagged



Reconstitution Protocol

USD 777.00

3 Weeks*

Size
    • 10 ug

Product images

Frequently bought together (4)
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Lenti ORF control particles of pLenti-C-mGFP-P2A-Puro, >1x10^7 TU/ml, 0.5 ml
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Forward primer to sequence targets cloned in expression vectors.
    • 1 nmol

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Reverse primer to sequence targets cloned in expression vectors.
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USD 71.00

Other products for "FRS2"

Specifications

Product Data
Type Human Tagged ORF Clone
Tag mGFP
Symbol FRS2
Synonyms FRS1A; FRS2A; FRS2alpha; SNT; SNT-1; SNT1
Vector pLenti-C-mGFP
E. coli Selection Chloramphenicol (34 ug/mL)
Mammalian Cell Selection None
Sequence Data
The ORF insert of this clone is exactly the same as(RC205842).
Restriction Sites SgfI-MluI      Cloning Scheme for this gene     
ACCN NM_006654
ORF Size 1536 bp
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_006654.3, NP_006645.2
RefSeq Size 6883 bp
RefSeq ORF 1527 bp
Locus ID 10818
UniProt ID Q8WU20
Cytogenetics 12q15
Domains IRS
Protein Families Druggable Genome
Protein Pathways Neurotrophin signaling pathway
MW 57.5 kDa
Gene Summary Adapter protein that links activated FGR and NGF receptors to downstream signaling pathways. Plays an important role in the activation of MAP kinases and in the phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, in response to ligand-mediated activation of FGFR1. Modulates signaling via SHC1 by competing for a common binding site on NTRK1.[UniProtKB/Swiss-Prot Function]
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.