Cyclin D1 (CCND1) (NM_053056) Human Tagged ORF Clone
CCND1 (Myc-DDK-tagged)-Human cyclin D1 (CCND1)
View "NM_053056" in other vectors (10)
Reward yourself with an Amazon® Card when get any 3 cDNA clones.
Specifications
Product Data | |
Product Name | Cyclin D1 (CCND1) (NM_053056) Human Tagged ORF Clone |
Type | Human Tagged ORF Clone |
Tag | Myc-DDK |
Symbol | CCND1 |
Synonyms | BCL1; D11S287E; PRAD1; U21B31 |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Cell Selection | Neomycin |
Sequence Data |
>RC204957 ORF sequence
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGAACACCAGCTCCTGTGCTGCGAAGTGGAAACCATCCGCCGCGCGTACCCCGATGCCAACCTCCTCA ACGACCGGGTGCTGCGGGCCATGCTGAAGGCGGAGGAGACCTGCGCGCCCTCGGTGTCCTACTTCAAATG TGTGCAGAAGGAGGTCCTGCCGTCCATGCGGAAGATCGTCGCCACCTGGATGCTGGAGGTCTGCGAGGAA CAGAAGTGCGAGGAGGAGGTCTTCCCGCTGGCCATGAACTACCTGGACCGCTTCCTGTCGCTGGAGCCCG TGAAAAAGAGCCGCCTGCAGCTGCTGGGGGCCACTTGCATGTTCGTGGCCTCTAAGATGAAGGAGACCAT CCCCCTGACGGCCGAGAAGCTGTGCATCTACACCGACAACTCCATCCGGCCCGAGGAGCTGCTGCAAATG GAGCTGCTCCTGGTGAACAAGCTCAAGTGGAACCTGGCCGCAATGACCCCGCACGATTTCATTGAACACT TCCTCTCCAAAATGCCAGAGGCGGAGGAGAACAAACAGATCATCCGCAAACACGCGCAGACCTTCGTTGC CCTCTGTGCCACAGATGTGAAGTTCATTTCCAATCCGCCCTCCATGGTGGCAGCGGGGAGCGTGGTGGCC GCAGTGCAAGGCCTGAACCTGAGGAGCCCCAACAACTTCCTGTCCTACTACCGCCTCACACGCTTCCTCT CCAGAGTGATCAAGTGTGACCCAGACTGCCTCCGGGCCTGCCAGGAGCAGATCGAAGCCCTGCTGGAGTC AAGCCTGCGCCAGGCCCAGCAGAACATGGACCCCAAGGCCGCCGAGGAGGAGGAAGAGGAGGAGGAGGAG GTGGACCTGGCTTGCACACCCACCGACGTGCGGGACGTGGACATC ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >RC204957 protein sequence
Red=Cloning site Green=Tags(s) MEHQLLCCEVETIRRAYPDANLLNDRVLRAMLKAEETCAPSVSYFKCVQKEVLPSMRKIVATWMLEVCEE QKCEEEVFPLAMNYLDRFLSLEPVKKSRLQLLGATCMFVASKMKETIPLTAEKLCIYTDNSIRPEELLQM ELLLVNKLKWNLAAMTPHDFIEHFLSKMPEAEENKQIIRKHAQTFVALCATDVKFISNPPSMVAAGSVVA AVQGLNLRSPNNFLSYYRLTRFLSRVIKCDPDCLRACQEQIEALLESSLRQAQQNMDPKAAEEEEEEEEE VDLACTPTDVRDVDI TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
Chromatograms |
CHROMATOGRAMS
![]() Sequencher program is needed, download here. |
Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
![]() |
Tag | Myc-DDK |
ACCN | NM_053056 |
ORF Size | 885 bp |
OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers. |
Reference Data | |
RefSeq | NM_053056.1, NM_053056.2, NP_444284.1 |
RefSeq Size | 4304 |
RefSeq ORF | 888 |
Locus ID | 595 |
Cytogenetics | 11q13.3 |
Domains | cyclin_C, CYCLIN, cyclin |
Protein Families | Druggable Genome, Stem cell - Pluripotency, Stem cell relevant signaling - DSL/Notch pathway, Stem cell relevant signaling - JAK/STAT signaling pathway, Stem cell relevant signaling - Wnt Signaling pathway |
Protein Pathways | Acute myeloid leukemia, Bladder cancer, Cell cycle, Chronic myeloid leukemia, Colorectal cancer, Endometrial cancer, Focal adhesion, Glioma, Jak-STAT signaling pathway, Melanoma, Non-small cell lung cancer, p53 signaling pathway, Pancreatic cancer, Pathways in cancer, Prostate cancer, Small cell lung cancer, Thyroid cancer, Viral myocarditis, Wnt signaling pathway |
MW | 33.7 kDa |
Gene Summary | The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with tumor suppressor protein Rb and the expression of this gene is regulated positively by Rb. Mutations, amplification and overexpression of this gene, which alters cell cycle progression, are observed frequently in a variety of tumors and may contribute to tumorigenesis. [provided by RefSeq, Jul 2008] |
Citations (1)
The use of this cDNA Clones has been cited in the following citations: |
---|
ETV4 Facilitates Cell-Cycle Progression in Pancreatic Cells through Transcriptional Regulation of Cyclin D1
,Tyagi, N;Deshmukh, SK;Srivastava, SK;Azim, S;Ahmad, A;Al-Ghadhban, A;Singh, AP;Carter, JE;Wang, B;Singh, S;,
Mol. Cancer Res.2017
,PubMed ID 29117940
[CCND1]
|
Documents
Product Manuals |
FAQs |
SDS |
Resources
cDNA Clone Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC204957L3 | Lenti ORF clone of Human cyclin D1 (CCND1), Myc-DDK-tagged |
USD 700.00 |
|
RC204957L4 | Lenti ORF clone of Human cyclin D1 (CCND1), mGFP tagged |
USD 760.00 |
|
RC204957L1 | Lenti ORF clone of Human cyclin D1 (CCND1), Myc-DDK-tagged |
USD 700.00 |
|
RC204957L4V | Lenti ORF particles, CCND1 (mGFP-tagged) - Human cyclin D1 (CCND1), 200ul, >10^7 TU/mL |
USD 1,020.00 |
|
RC204957L3V | Lenti ORF particles, CCND1 (Myc-DDK tagged) - Human cyclin D1 (CCND1), 200ul, >10^7 TU/mL |
USD 910.00 |
|
RG204957 | CCND1 (GFP-tagged) - Human cyclin D1 (CCND1) |
USD 560.00 |
|
RC204957L1V | Lenti ORF particles, CCND1 (Myc-DDK tagged) - Human cyclin D1 (CCND1), 200ul, >10^7 TU/mL |
USD 910.00 |
|
RC204957L2V | Lenti ORF particles, CCND1 (mGFP-tagged) - Human cyclin D1 (CCND1), 200ul, >10^7 TU/mL |
USD 1,020.00 |
|
SC119035 | CCND1 (untagged)-Human cyclin D1 (CCND1) |
USD 300.00 |
|
RC204957L2 | Lenti ORF clone of Human cyclin D1 (CCND1), mGFP tagged |
USD 760.00 |
USD 299.00
USD 550.00
USD 360.00