Aquaporin 4 (AQP4) (NM_001650) Human Tagged ORF Clone

CAT#: RC204693L1

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  • LentiORF®

Lenti ORF clone of Human aquaporin 4 (AQP4), transcript variant a , Myc-DDK-tagged

 Cited in 1 publication.

  View "NM_001650" in other vectors (11)

USD 700.00


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Size
    • 10 ug


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Specifications

Product Data
Product Name Aquaporin 4 (AQP4) (NM_001650) Human Tagged ORF Clone
Symbol AQP4
Synonyms MIWC; WCH4
Vector pLenti-C-Myc-DDK
E. coli Selection Chloramphenicol (34 ug/mL)
Sequence Data
The ORF insert of this clone is exactly the same as(RC204693).
Restriction Sites SgfI-MluI      Cloning Scheme for this gene     
Tag Myc-DDK
ACCN NM_001650
ORF Size 969 bp
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Product Components The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Reference Data
RefSeq NM_001650.4, NP_001641
RefSeq Size 5216
RefSeq ORF 972
Locus ID 361
Cytogenetics 18q11.2
Domains MIP
Protein Families Druggable Genome, Transmembrane
MW 34.6 kDa
Gene Summary This gene encodes a member of the aquaporin family of intrinsic membrane proteins that function as water-selective channels in the plasma membranes of many cells. This protein is the predominant aquaporin found in brain and has an important role in brain water homeostasis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. Additional isoforms, resulting from the use of alternative in-frame translation initiation codons, have also been described. Recent studies provided evidence for translational readthrough in this gene, and expression of C-terminally extended isoforms via the use of an alternative in-frame translation termination codon. [provided by RefSeq, Jun 2018]

Citations (1)

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