c-Myc(MYC) (NM_002467) Human Tagged ORF Clone

CAT#: RC201611L2

  • LentiORF®

Lenti ORF clone of Human v-myc myelocytomatosis viral oncogene homolog (avian) (MYC), mGFP tagged

  View "NM_002467" in other vectors (12)

USD 860.00


Availability*
In Stock

Size
    • 10 ug


Product images

Specifications

Product Data
Product Name c-Myc(MYC) (NM_002467) Human Tagged ORF Clone
Symbol MYC
Synonyms bHLHe39; c-Myc; MRTL; MYCC
Vector pLenti-C-mGFP
E. coli Selection Chloramphenicol (34 ug/mL)
Sequence Data
The ORF insert of this clone is exactly the same as(RC201611).
Restriction Sites SgfI-MluI      Cloning Scheme for this gene     
Tag mGFP
ACCN NM_002467
ORF Size 1365 bp
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Product Components The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Reference Data
RefSeq NM_002467.3, NP_002458
RefSeq Size 2379
RefSeq ORF 1365
Locus ID 4609
Cytogenetics 8q24.21
Domains HLH, Myc_N_term, Myc-LZ
Protein Families Stem cell relevant signaling - JAK/STAT signaling pathway, Stem cell relevant signaling - TGFb/BMP signaling pathway, Stem cell relevant signaling - Wnt Signaling pathway, Stem cell - Pluripotency, Embryonic stem cells, Induced pluripotent stem cells, Transcription Factors, Druggable Genome
Protein Pathways MAPK signaling pathway, ErbB signaling pathway, Cell cycle, Wnt signaling pathway, TGF-beta signaling pathway, Jak-STAT signaling pathway, Pathways in cancer, Colorectal cancer, Endometrial cancer, Thyroid cancer, Bladder cancer, Chronic myeloid leukemia, Acute myeloid leukemia, Small cell lung cancer
MW 50.5 kDa
Gene Summary This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes. Amplification of this gene is frequently observed in numerous human cancers. Translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients. There is evidence to show that translation initiates both from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site, resulting in the production of two isoforms with distinct N-termini. [provided by RefSeq, Aug 2017]

Other Versions

Frequently bought together (3)
Lenti-vpak packaging kit - packaging plasmids and transfection reagent
    • 10 rxns

USD 550.00


LentiORF control particles of pLenti-C-mGFP-P2A-Puro, >1x10^7 TU/ml, 0.5 ml
    • 0.5 ml

USD 300.00


c-Myc (c-Myc ) mouse monoclonal antibody, clone OTI3F2 (formerly 3F2)
    • 100 ul

USD 360.00

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
40% off proteins and antibodies
68 Mouse Clones