Arid4b (NM_194262) Mouse Tagged Lenti ORF Clone
CAT#: MR217634L4
- LentiORF®
Lenti ORF clone of Arid4b (mGFP-tagged) - Mouse AT rich interactive domain 4B (RBP1-like) (Arid4b), transcript variant 1
"NM_194262" in other vectors (4)
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USD 365.00
Specifications
Product Data | |
Type | Mouse Tagged ORF Clone |
Tag | mGFP |
Symbol | Arid4b |
Synonyms | BCAA; BRCAA1; RBBP1L1; Rbp1l1; SAP180 |
Vector | pLenti-C-mGFP-P2A-Puro |
E. coli Selection | Chloramphenicol (34 ug/mL) |
Mammalian Cell Selection | Puromycin |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR217634).
|
Restriction Sites | SgfI-MluI Cloning Scheme for this gene Plasmid Map |
ACCN | NM_194262 |
ORF Size | 3942 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_194262.2, NP_919238.1 |
RefSeq Size | 6113 bp |
RefSeq ORF | 3945 bp |
Locus ID | 94246 |
UniProt ID | A2CG63 |
Cytogenetics | 13 5.29 cM |
Gene Summary | Acts as a transcriptional repressor. May function in the assembly and/or enzymatic activity of the Sin3A corepressor complex or in mediating interactions between the complex and other regulatory complexes (By similarity). Plays a role in the regulation of epigenetic modifications at the PWS/AS imprinting center near the SNRPN promoter, where it might function as part of a complex with RB1 and ARID4A (PubMed:17043311). Involved in spermatogenesis, together with ARID4A, where it functions as a transcriptional coactivator for AR (androgen receptor) and enhances expression of genes required for sperm maturation. Regulates expression of the tight junction protein CLDN3 in the testis, which is important for integrity of the blood-testis barrier (PubMed:23487765). Plays a role in myeloid homeostasis where it regulates the histone methylation state of bone marrow cells and expression of various genes involved in hematopoiesis. May function as a leukemia suppressor (PubMed:18728284).[UniProtKB/Swiss-Prot Function] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
MC224223 | Arid4b (untagged) - Mouse AT rich interactive domain 4B (RBP1-like) (Arid4b), transcript variant 1, (10ug) |
USD 1,259.00 |
|
MG217634 | Arid4b (tGFP-tagged) - Mouse AT rich interactive domain 4B (RBP1-like) (Arid4b) transcript variant 1, (10ug) |
USD 1,344.00 |
|
MR217634 | Arid4b (Myc-DDK-tagged) - Mouse AT rich interactive domain 4B (RBP1-like) (Arid4b), transcript variant 1 |
USD 1,144.00 |
|
MR217634L3 | Lenti ORF clone of Arid4b (Myc-DDK-tagged) - Mouse AT rich interactive domain 4B (RBP1-like) (Arid4b), transcript variant 1 |
USD 1,444.00 |
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