OriGene Logo

Aurkc (NM_001080966) Mouse Tagged ORF Clone

  • TrueORF®
Be the first to review this product
SKU
MG216975
Aurkc (tGFP-tagged) - Mouse aurora kinase C (Aurkc) transcript variant 2, (10ug)
Interest in protein/lysate? Submit request here!
ORF Plasmid:
tGFP DDK
AAV Particle:
DDK
  $500.00
3 Weeks*
Bulk Requests & Clone Modifications

Frequently Bought Together (4)

TA150041 Mouse monoclonal turboGFP antibody, clone OTI2H8
100 ul
$447.00
CC100003 DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)
5 x 200 ul
$170.00
PRIMER Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
100 pmol
$59.00
PS100010 pCMV6-AC-GFP, mammalian vector with C-terminal tGFP tag, 10ug
10 ug
$780.00

Other products for "Aurkc or NM_001080966"

Specifications
Specifications
Product Data
Type Mouse Tagged ORF Clone
Target Symbol Aurkc
Synonyms AIE1; AIK3; ARK-3; IAK3; Stk13
Vector pCMV6-AC-GFP
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
ORF Nucleotide Sequence
>MG216975 representing NM_001080966
Red=Cloning site Blue=ORF Green=Tags(s)

TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
GCCGCGATCGCC

ATGGAGCCCAGCACCTCAACCAGGAAGCATTTCACCATCAATGACTTTGAAATCGGGCGTCCTCTGGGCA
GGGGGAAATTTGGGCGTGTGTACTTGGCTCGGCTCAAGGAAAATCATTTCATCGTGGCCCTGAAGGTCCT
CTTCAAGTCTGAGATAGAGAAGGAGGGATTGGAGCACCAACTTCGCAGGGAAGTGGAGATCCAGGCACAC
CTACAACACCGGAACATCCTTCGCCTGTACAACTACTTCTATGATGACACTCGGATATACTTAATTCTGG
AGTATGCTCCAGGAGGAGAGCTCTATAAGGAGCTTCAGAGACATCAGAAGTTGGACCAGCAGCGTACAGC
CACGATAATACAGGAGTTGTCAGATGCCCTGACCTACTGCCATGAGAAGAAGGTGATTCACAGGGACATC
AAGCCAGAGAATCTCCTGCTGGGCCTCAATGGTGAGGTGAAGATCTCAGACTTTGGGTGGTCTGTGCATA
CCCCCTCTCTCAGGAGAAAGACAATGTGTGGGACTCTGGACTACTTGCCCCCGGAAATGATAGCGCAGAA
ACCGTACAATGAGATGGTTGATCTGTGGTGCATTGGGGTGCTCTGCTATGAGCTGCTGGTGGGGAAGCCA
CCCTTTGAGAGCAGCACCTCCAGTGAGACATACAGACGCATCCGCCAGGTGGATTTTAAGTTTCCTTCAT
CAGTACCTGCAGGAGCCCAGGACTTGATCTCCAAGCTTCTTAGGTACCATCCTTCAGAGCGGCTGAGCCT
GGCCCAGGTCCTGAAGCACCCCTGGGTCAGGGAACACTCTCGAAGGGTGCTTCCTTGC

ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
Protein Sequence
>MG216975 representing NM_001080966
Red=Cloning site Green=Tags(s)

MEPSTSTRKHFTINDFEIGRPLGRGKFGRVYLARLKENHFIVALKVLFKSEIEKEGLEHQLRREVEIQAH
LQHRNILRLYNYFYDDTRIYLILEYAPGGELYKELQRHQKLDQQRTATIIQELSDALTYCHEKKVIHRDI
KPENLLLGLNGEVKISDFGWSVHTPSLRRKTMCGTLDYLPPEMIAQKPYNEMVDLWCIGVLCYELLVGKP
PFESSTSSETYRRIRQVDFKFPSSVPAGAQDLISKLLRYHPSERLSLAQVLKHPWVREHSRRVLPC

TRTRPLE - GFP Tag - V
Restriction Sites SgfI-MluI Cloning Scheme for this gene | Plasmid Map
ACCN NM_001080966
ORF Size 828 bp
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_001080966.1, NP_001074435.1
RefSeq Size 1454 bp
RefSeq ORF 831 bp
Locus ID 20871
UniProt ID O88445
Cytogenetics 7 4.06 cM
Summary Serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Plays also a role in meiosis and more particularly in spermatogenesis. Has redundant cellular functions with AURKB and can rescue an AURKB knockdown. Like AURKB, AURKC phosphorylates histone H3 at 'Ser-10' and 'Ser-28'. AURKC phosphorylates the CPC complex subunits BIRC5/survivin and INCENP leading to increased AURKC activity. Phosphorylates TACC1, another protein involved in cell division, at 'Ser-228'.UniProtKB/Swiss-Prot Function
Reviews
Write Review
 
 
 
 
 

Be the first to review this product

Please note:
Only reviews with images are eligible for a $20/20€ Amazon gift card.
Reviews without images are eligible for a $10/10€ Amazon gift card.
For more details about the terms and conditions, please visit the promotion page.

Documents
Resources
"NM_001080966" in other vectors (3)
SKU Description Size Price
MR216975 Aurkc (Myc-DDK-tagged) - Mouse aurora kinase C (Aurkc), transcript variant 2 10 ug
$289.00 $300.00
MR216975L3 Lenti ORF clone of Aurkc (Myc-DDK-tagged) - Mouse aurora kinase C (Aurkc), transcript variant 2 10 ug
$600.00
MR216975L4 Lenti ORF clone of Aurkc (mGFP-tagged) - Mouse aurora kinase C (Aurkc), transcript variant 2 10 ug
$600.00

file-alt Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.