Il31ra (NM_139299) Mouse Tagged ORF Clone
Specifications
| Product Data | |
| Type | Mouse Tagged ORF Clone |
|---|---|
| Target Symbol | Il31ra |
| Synonyms | CRL3; GLM-R; Glmr; GPL; NR10 |
| Vector | pCMV6-AC-GFP |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data | |
| Restriction Sites |
SgfI-MluI Cloning Scheme for this gene
|
Plasmid Map
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| ACCN | NM_139299 |
| ORF Size | 2148 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_139299.2, NP_647460.2 |
| RefSeq Size | 3680 bp |
| RefSeq ORF | 2151 bp |
| Locus ID | 218624 |
| UniProt ID | Q8K5B1 |
| Cytogenetics | 13 D2.2 |
| Summary | Associates with OSMR to form the interleukin-31 receptor which activates STAT3 and to a lower extent STAT1 and STAT5. May function in skin immunity (PubMed:15184896). Mediates IL31-induced itch, probably in a manner dependent on cation channels TRPA1 and TRPV1 (PubMed:24373353). Positively regulates numbers and cycling status of immature subsets of myeloid progenitor cells in bone marrow in vivo and enhances myeloid progenitor cell survival in vitro (PubMed:17379091).UniProtKB/Swiss-Prot Function |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
"NM_139299" in other vectors (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| MC221042 | Il31ra (untagged) - Mouse interleukin 31 receptor A (Il31ra), (10ug) | 10 ug |
$985.00
|
|
| MR216199 | Il31ra (Myc-DDK-tagged) - Mouse interleukin 31 receptor A (Il31ra) | 10 ug |
$983.00
|
|
| MR216199L3 | Lenti ORF clone of Il31ra (Myc-DDK-tagged) - Mouse interleukin 31 receptor A (Il31ra) | 10 ug |
$1,283.00
|
|
| MR216199L4 | Lenti ORF clone of Il31ra (mGFP-tagged) - Mouse interleukin 31 receptor A (Il31ra) | 10 ug |
$1,283.00
|
|
Plasmid Map for MG216199
Download sequence for
Cloning scheme for MG216199
Circular map for MG216199
Citations
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