Lrit3 (NM_001287224) Mouse Untagged Clone

CAT#: MC228657

Lrit3 (untagged) - Mouse leucine-rich repeat, immunoglobulin-like and transmembrane domains 3 (Lrit3)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Lrit3
• Synonyms: Gm421
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC228657 representing NM_001287224
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGTGGCTCTCGGCCTGCCTGTGCCTTGTGCTTAGCTTCCTGGGAGGAGTGAACGGTACCTGCCCTTCTC
  AGTGCTCCTGTGAGTATCACGGCAGACATGACGGCTCAGGATCAAGGTTAGTGTTGTGTAACGACCTGGA
  TATGAACGAAGTCCCAGCAAACTTCCCCGTGGACACCTCGAAGCTTCGCATAGAGAAGACTGTGGTCCGC
  AGGCTCCCCGCCGAGGCCTTCTACTACCTGGTGGAGCTGCAGTACCTCTGGCTGGCTTACAACTCAGTGG
  CCAGCATAGAAACCAGTAGCTTCTATAACCTGAGGCAGCTGCACGAGTTGCGTTTGGATGGGAATTCTCT
  GACCGCTTTCCCTTGGGTGTCTCTGCTGGACATGCCCCACCTGAGGACGCTGGACTTACACAATAACAGA
  ATAGCCAGTGTGCCAAACGAGGCGGTCAGATATCTGAGGAACCTCACCTGCTTGGACTTGTCGAGCAACC
  GACTGACCACGCTGCCACCAGATTTCCTAGACAGCTGGTCTCATTTAGCCGTGACACCGTCTAGAAGCCC
  GGACTTTCCACCGAGAAGAATTATTCTTGGTTTGCAGGACAACCCCTGGTTCTGTGACTGTCACATTTCC
  AAGGTGATCGAGCTGTCGAAAGTCACCGACCACGCTGTTGTTCTTCTTGATCCTCTGATGGTCTGCAGTG
  AACCCGAGCGCTTCCAAGGAATCTTGTTCCAGAGGGTAGAGTTGGAAAAGTGTCTGAAGCCGTCCGTGAT
  GATGTCAGCTACCAAAATCACATCTGCTCTGGGTAGTAATGTTCTGCTGAGATGTGATGCCAAGGGTCAC
  CCCACCCCACAGCTGACGTGGACCAGATCCGACGGCTCCACAGTTAACTATACAGTAATTCAGGAGTCTC
  CAGGAGAAGGCATCAGATGGTCCATCATAAGCTTGACCAGCATCTCTCACAAGGATGCTGGGGATTACAG
  GTGTAAAGCCAAAAATCTGGCAGGGATTTCGGAAGCTGTGGTTACTGTGACAGTTGTTGGTGGTGTTACG
  ACCACCCTATCACCAGACAGTTCAGAAAGAAGTCCTGGAGAGCCCCCTGAGCAGCATCCCCAGCCAGGAT
  TAGGAGGATCAACACCTCCATCTAAATCCTGGTTATCACCCGGGCTCACTTCCGCTCCTTCCTACCCCAC
  CCCCTCAGCAGCTCTCTATACATCTACGTGGTCCCCTCCTCCCTCCTCCTTGCCTCCCATCTTCTCAGCT
  GCTTCTGCAACCACCAGTGTACAAACCAGCATCTCAGGACGCACCGCCAGGACTAGCCACCAGCCACCCC
  TGCTCCACCCCGGTGGGAAAAGCAATGCGAAGATAGAGAAGAACGGAAGGAAGTTTCCTCCGCTCAGCGC
  AAGTAAGAAAGAAGAGTTGGCGTTGTTGGATCAGGCAGCGCCAATGGAAACAAACGTCACTATCAAAGAC
  CTCAGGGTGGCCCGTGAAACCGGCGTGAGTGTGACTCTGATGTGGAACAGCAGCAGCAGCACACAAGAGT
  CCTCTGTGACTGTGCTGTATTCTAAGTACGGTGAGAAGGACCTGCTGTTAGTGAATGCAGACGACTATGG
  CAAGAACCAGGCAACCATAAATGGCCTAGAGCCCGGAAGTCAGTATGTGGCATGTGTCTGTCCAAAAGGA
  GTGGGTCCCCGGGAGGATCTGTGTATCACCTTTTCTACCAACAGAGTTGAGGGGCGTGGCTCACAGTGGT
  CATTGCTCCTCGTGGTGACCAGTACTGCCTGTGTTATAGTCGTGCCCCTAATTTGTTTCTTATTATATAA
  AGTCTGCAAATTGCAATGCACATCGGACCCTTTCTGGGAAGAGGATTTGTCAAAAGAGACATATATCCAA
  TTTGAGACCCTGTCACCCAGGTCACAGAGTATAGGGGAGCTCTGGACCCGGAGGCACAGAGACGATGGCG
  AGAGGTTGCTGCTATGCTCCCAGTCAAGTGTGGACTCCCAGATGAATCTTAAGAGCGATGGCTGTAGGAC
  GGAGTATTATGGCTGA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_001287224
• Insert Size: 2046 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: Clone contains native stop codon, and expresses the complete ORF without any c-terminal tag.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001287224.1, NP_001274153.1
• RefSeq Size: 2046 bp
• RefSeq ORF: 2046 bp
• Locus ID: 242235
• UniProt ID: W8DXL4
• Cytogenetics: 3 G3
• Gene Summary: Required in retinal ON-bipolar cells for normal localization of the cation channel TRPM1 at dendrite tips (PubMed:25997951). May also have a role in cone synapse formation (PubMed:25997951). Might facilitate FGFR1 exit from the endoplasmic reticulum to the Golgi (By similarity). Could be a regulator of the FGFRs (By similarity).[UniProtKB/Swiss-Prot Function]