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Scn3b (NM_001083917) Mouse Untagged Clone

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SKU
MC226342
Scn3b (untagged) - Mouse sodium channel, voltage-gated, type III, beta (Scn3b), transcript variant 3
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ORF Plasmid:
Tag Free DDK
AAV Particle:
DDK
  $330.00
2 Weeks*
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Specifications
Specifications
Product Data
Type Mouse Untagged Clone
Target Symbol Scn3b
Synonyms 1110001K16Rik; 4833414B02Rik; Scnb3
Vector pCMV6-Entry
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
Fully Sequenced ORF
>MC226342 representing NM_001083917
Red=Cloning site Blue=ORF Orange=Stop codon

TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
GCCGCGATCGCC

ATGCCTGCCTTCAACAGATTGCTTCCCCTAGCTTCTCTAGTGCTCATCTACTGGGTCAGAGTCTGCTTCC
CTGTGTGTGTAGAAGTACCCTCGGAGACAGAAGCCGTGCAGGGCAATTCCATGAAGCTGAGATGCATCTC
CTGCATGAAGAGGGAGGAGGTGGAGGCCACCACTGTAGTGGAGTGGTTCTACAGGCCTGAGGGCGGTAAA
GATTTCCTTATATATGAGTATCGAAATGGCCACCAGGAGGTGGAGAGCCCCTTCCAAGGTCGTCTGCAGT
GGAATGGGAGCAAAGACCTGCAGGACGTATCCATCACTGTTCTCAATGTCACTCTGAATGACTCTGGCCT
CTACACATGTAATGTGTCCAGGGAGTTTGAGTTCGAAGCACACCGGCCCTTTGTGAAGACCACAAGACTA
ATACCCCTGCGAGTCACTGAAGAGGCGGGAGAAGACTTCACCTCCGTGGTCTCGGAAATCATGATGTACA
TCCTCCTGGTCTTCCTCACCTTGTGGCTGTTTATTGAGATGATCTATTGCTACAGAAAGGTCTCTAAGGC
CGAAGAGGCAGCTCAGGAAAATGCGTCTGACTACCTTGCTATCCCTTCAGAGAACAAGGAGAACTCTGTG
GTACCCGTGGAGGAATAA

ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
ACAAGGATGACGACGATAAGGTTTAA
Restriction Sites SgfI-MluI |
ACCN NM_001083917
Insert Size 648 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation Clone contains native stop codon, and expresses the complete ORF without any c-terminal tag.
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_001083917.1, NP_001077386.1
RefSeq Size 4177 bp
RefSeq ORF 648 bp
Locus ID 235281
UniProt ID Q8BHK2
Cytogenetics 9 A5.1
Summary Modulates channel gating kinetics. Causes unique persistent sodium currents. Inactivates the sodium channel opening more slowly than the subunit beta-1. Its association with NFASC may target the sodium channels to the nodes of Ranvier of developing axons and retain these channels at the nodes in mature myelinated axons (By similarity).UniProtKB/Swiss-Prot Function
Transcript Variant: This variant (3) differs in the 3' UTR, compared to variant 2. Variants 2, 3 and 5 encode the same protein (isoform a).
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Documents
Resources
"NM_001083917" in other vectors (1)
SKU Description Size Price
MR228553 Scn3b (myc-DDK-tagged) - Mouse sodium channel, voltage-gated, type III, beta (Scn3b), transcript variant 3 10 ug
$289.00 $300.00

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