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Setx (NM_198033) Mouse Untagged Clone
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Frequently bought together (3)
Other products for "Setx"
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Symbol | Setx |
| Synonyms | A130090N03; A930037J23Rik; Als4; AOA2; AW060766; mKIAA0625; SCAR1; Sen1 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC225382 representing NM_198033
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGAGCACATGCTGTTGGTGTACTCCAGGTGGGTCTTCCACCATTGATGTCCTAAAGCGCTATGCATCTA GCACTGGGTCAAGTGAATTTCAGACAGCTGATGAAGACCTCTGCTACTGCTTAGAGTGTGTGGCTGAGTA CCACCGAGCCAGAGATGAGGTGCCGTTCTTGCACGAGGTTTTATGGGAGCTAGAAACCTTACGCCTCGTA AGTCACTTTGAGAAGTCCATGAAGGCAGAAGCTGAAGATGACGATGATTTATATATAGTAGACAACAATG GAGAGGAACAGCTGTTTGACTGTAGTGGCCAAGATTTTGAAAATAAGCTTCGAGTTCCTCTTTTTGAAAT ACTGAAGTACCCTTACTTGCTTCTGCATGAGCGTGTTAATGAACTGTGTGTGGAAGCGCTTTGCCGAATG GAACAAAACAATTGCTCCTTTCAGGTTTTTGACAAATATCCAGGCATCTATTTGTTTTTGGTTCATCCCA ATGAAATGGTTCGGCGATGGGCTATTCTGACTGCAAGAAACCTGGGGAAGGTGGACAGAGATGACTATTA TGACTTACAGGAAGTTTTAACTTGCCTTTTTAAAGTCATTGAGCTGGGGCTTTTGGAAAGTCCAGACATT TACACATCTTCTGTGCTTGAAAAAGGCAAACTGATCCTTTTGCCTGCACACATGTATGATACTACCAACT ACAAAAACTATTGGCTAGGTATTTGCATGTTGTTGACTATTCTTGAGGAGCAAGCCATGGATTCACTGTT GCTGGGCTCAGACAAGCAAAATGATTTTATGCAATCAATTCTTCACACCATGGAGAAGCAATCGGATGAT GATAGCATGGATCCTTTTTGGCCAGCATTACACTGTTTCATGGTGATTCTTGATCGCCTTGGATCTAAGG TATGGGGTCAACTTATTGACCCTATTGAAGCATTTCAAACCATCATTAACAACGAGAGCTACAACAGAGA GATCCAGAATATACGGAACAGCTCCATAAGGACCAAGTTAGAACCGGAGCCACATTTTGATGATATGGTG ACGTGCAGCCAGATTGTTTATAACTTTAATCCTGAAAAGACCAAAAAGGATTCTGGGTGGAGATCAGCCA TTTGTCCAGATTATTGTCCAAACATGTATGAAGAAATGGAAACATTAGCCAATGTACTTCAGTCAGATAT TGGTCAAGATATGCGTGTTCATAACAGCACCTTTCTGTGGTTCATACCTTTTGTTCAGTCACTCATGGAT CTTAAGGATTTGGGTGTGGCTTACATAGTAGAAGTTATTCATCATCTATACTCAGAAGTCAAAGATGTCC TCAACCAGACAGATGCTGTGTGTGACAAAGTCACTGAATTTTTTATTCTGATTTTAATATCAGTGATTGA GCTGCATAGAAATAAAAAATGCTTGCATCTGCTGTGGGTGAGTTCTCAGCAGTGGGTAGAAGCTGTTGTG AAGTGTGCCAAGCTTCCTACTACCGCATTTGTCCGGAGTTGTGAGAAGTCACCTGGAAGTACCTCCAGAG GAGCAGCAATAATGTCGTCCTTGGCGTTGCATTCGGTGCAGTCTAACTCTGTCCAGCTTGCTTGTGTACA GTTGATTAGAGGTCTCCTCAAAGAAGGTTATCAGCTTGGTCAGCAAACACTTTGTAAGCGGTTCTGGGAT AAGCTTAACTTATTCCTTCGAGGAAATTTGTCTCTGGGTTGGCAATTGACTGGTCAAGAAACCCATGAGT TACAAATGTGTTTGAAACAAATAATTAGAAACATAAAATTCAAAATGCCCCAATATAGCACTTTTGGGGA TTCAACTTCTACATTTAAAACCCCTCCATCTTTTAAAGAAGAAAGTGATAAAATAGACAGGAAGCATAAA AAAAACATTTATTGTTTGGAAAATTGCAGTCCAGTGTCTTCTAAAGAGCCAATGAAAGCTGACACCCATC GAGTATTGATGAAAGTAAATACTACAGAAGAGGAGAACTTCAAGCAGCATTACATTGATTTGAATGAAGA AGAGCAAGAGCCTCTTCCAGCTGAGTTGTGCTTGAAGCAGAAAAGTGAGGCCCTTTTTTCTGAAAGTGCT CAAGAGCAAGTTAAAATTAGCGCAGAGAAGTCTGGGAAAGAAAGCTCTTCATATGCACCATCAAATAGTA CTTCAAGAAATGGTCCAGAATGGGGATGTGACAGAGGAGTGATAATGTCAGCACATTCATTGACTGATTC TAGCAGTGATTTTATGGAACAGGTATCTACATCAAATGAAGATGTCTCATTAAAGGATGGCTCTGTTGGT AAAACTTCAAAACCAAGTTTCAAATTACAGAAAGATGAAATTTGTGCAAAGTTATCACATGTCATAAAGA AGCAAATCAGGAAAAGTACTTTGGTAGATAATATTATCGATCTAGAGGAAAATACAGCTATATCTGACCT TGAGAACTGTTCAGGAACAGATGGAGGAGCTCTAAAGGAAGATAGTATTGGACACAATGTCCCTTCAGAC CCTGTTCTGGATGACAAGCATGAAGAGCAAAAATCTCAAAACAGTTCATTATTCAAGAAAGAGATAAAGA GTGAGGAGTTGGATAATAGTAGTTCTGATGATGAAGACAAGCTTCAAATCCAGGAAGGCCGTGCTGACGA TGATTTGGTATCATTTACAGAAGTTACTGATACACTGGTGAAAGCTCCATGTGAGGGTCATGTAAAGATG GTAGTTGAATCAAGAGATAAGGAAATGAGAGAGAGTACAGCGTTGACTTCTAACTTGGTAGAAGGACAGG TGCCTCATGACAGTAGCAAGCCTTTGGTTGCAGGTCGTCAAATAGACCTCTGTAACATAACTTTAATATC TCAAACCACTGTTATTCAATTTCCATCAGGTTTAAGTAAACAGAATTCATTTCAGCTACAAAAAGGTGAT AAAAGATGTTTGACAGCTAACCAAAACAGTGCTGCCACCTGCCGTGGACAAGTTATTGTGATTTCAGATT CTGACGAAGAAGAGGATGAGGATGAAGATGAAAGAAGTAGTAGTGAGGAAAACATCAAACAGAGTAAAGC ATGCATAGGGAAAGACTGCTCAGAGCATCGTAGCTTGGCAGTTAATGCCAGTGTGGAGAAGCAGCTTGTA AAAGAGGAAGAAAGGTACCCTGTAGAATTTGAAGACTCTGAATCTCAGGTTTTTGAGTTTGAAAGCTCAT CTGAAGTCTTTTCAGTTTGGCAAGATCATAAAATAGACAGCAAAAACTCCCTTCAAGGGGAACAGAAGAG CTATGTAACTCATGTAGCTGATAGTACAAACAATAACTTGGGTTGTGGTGACTCTGTGTCTGAAGAGGTT GTTAGAAACAAAGCAGAGGGAGTTAAAGAGCATGCAGGACCACATAGTAGTGTTTCTGCTGAGGAATTTT GTAAAACTGGAGTAAAAAAACCTAAGAGGAAACGCTATGACAAAGTTACAGCTGAAGATCCTCAGAGGCC TTCCTCTTCTGTTGGAACTGATCAATTGCCTGATCGCAGAGATCTTACTGAAAGTGATTTAAAGAGTGCA GACATGGGGATGGCAACTCCCAGTTCAAGTGTTGAGAGAGATTCTACAATTTTACAGAAGTCTACAAAAT CTCGAACTCACTCAAAACCTGTTAGGAAAGTTCCAGCCTCTAAGGCAACTAAGAAAACACATTCAGACAC CAGAAGAGGACAGTCTAAGAGTTCATGTTACATAAGTTGTAGAACTTCTCCTGCTATTGTGCCACCAAAG AAGCTTCGTCAGTGTCCAGAGCCAACTTCAACAGTTGAAAAACTTGGTCTGAAAAAAGCCCCTAGGAAGG CATTTGAGTTGTCCCAGAGGTCTCTGGAGTGTATAGTCCAATTACGTGACCACGGGAAGACTGTTGGAGT AGTTGACGCCCCCAAGAAAGCTAAATTAATTTCTCCTCAGACTCTTTCTATCAAAAATAATAAGAAGCTT CTGACAAGCCAGGATCTTCAATTTCAAAGGCTTATGAGATCCAGATCACATAAAAAACGAGACTTTGATT ACAAAAATACTGATACTGTAAGAGTGTCACGCATAGTACAGGGATCAGATGTACTTGAAGCAGACTCTGA TGAGCCAGATGATCATAGAGTAAGTGAGCCACTTGCCATCAGTAATGAAAAACAGTTAGCAAAATGCATG CTTTCCAAAACAGAAGTGGCAGAAGCCTCTTCTGATCCTTGGGTGACAGGTATAACTTGTCTTGTGAACC AGTGTGAATCTAGAGTGTTAAGTGGAGGAGTGCCAACAGATGTGGTGATGGTCTCTGCTTCAGAGGACCC TGTGGATGGAGGTGCTGTCACAGTTCAAGTTGGGGAGGTGGCATCTGTGAAAGCTGCAGAGCCAGCGTCT AGTAGTGATACAGATGATGATGACAACTTATTCCTAACACAACATGATCCTCAAGATATGGATCTGTGCT CACAGTTGGAAAATAAAACCATTATCGTGGCTCATAAAAAAGATACAGTTCAGAGAGAAGATTCTTTAAG TCGGCCTCAGTTGGAGTCTTTGAGTATCACAAAGTGTAAATACAAAGACTGTGTCGAAACTACAAAAAAC CAGGGTGAATACTGCCCAAGACACTCTGAAGCTAAAGCAGCAGATGACGGCCTGTTCCGTAAACCTGGCT TGCCTCTTTCTGTAGCCAGGCCCTTGAGACCTACTACTACCAAGATATTTAGCTCAAGCAGCGCTTCACG AACTGCCAATCTTTCCAAGTCTTTGGAAAGTACTACACTTCAGCAGTCAGCACTAAAAAATAAGTCAAGT GGAGCGCAGCCTAATTTGAAGGTGACACCACCCTCTTCCATGGGTTCTCAGAAGCCAGTGGCTGAGGTGA AAAGTCTATGCAATATTTTTCATTTTCAGACTCCAAGCAGTTCCAGCAAACAGAGTTGCAAGCTTACATT TAGTGAGAACAGGCCTACATCAGCTGCTTCTCCAGTGAATATTCTCTTGCCATCGCAGTCTATCTTTGAC ACCTTCATTAAAGAGGTCTTAAAATGGAAATACCAAATGTTTTTGAACTTTGATAAGTGTGGTGCTCCAA CAAGTCTCTGTCAGTCTATCTCAAGACCTGTGCCTGTCCGATTTCAAGATTGTGCAGAATATTTTAATGT TTTTCTACCTTTGATTATATTGAATGCTTTTGAAACAGTGGCACAGGAATGGCTGAGCTCTCCAAATAAA GAGAATTTCTATCAGTTGCAATTACGAAAATTTCCAGCTGACTATAAAAAATACTGGGAGTTTCTGATTT ACTTGAACGAATCTGAACTTGCTAAACAGCTTCACCCAAAGGAAAATGATCTGGTGTTTCTGGCTCCTGA GAAGAGTTATATGGACAGGCATGGCATGCAAGATTGCAGTCACTATTACTGTGGCTATGTTCATAAGTTT CGTCGCACTTCAGTTATGCGCAGTGGGAAAGCTGAGTGTTCATTATGCATACAGACACAAGATACCTTGC CAGCCAGTGTAAAAAATCTTACAAGATGCATTGTGATCAGTTCTCTGGTAACTACACAGAGGAAATTGAA AGCCATGTCTCTGTTGAGTAGTCGGAACCAGTTGGCCAGAGCTGTTCTAAATCCAAACCCCATGGACTTC TGTACCAAAGATCTACTAACTACAACTTCTGAAAGAATTGTTGCCTACTTAAAAGACTTTAATGAAGACC AAAAGAAAGCCATAGAAACTGCATATGCCATGGTGAAACACTCACCATCCGTTGCCAAAATCTGTCTGAT TCATGGACCACCTGGAACAGGAAAATCCAAAACTATTGTTGGTCTCTTGTACCGCTTACTGACAGAGAAC CAGAGGAAGGGCCATTCAGATGAAAATTTCAATGCCAAAATCAAACAAAATCGAGTCCTCGTGTGTGCAC CTTCCAATGCGGCGGTTGATGAACTTATGAAAAAAATTATCCTCGAATTTAAAGAAAAATGTAAAGACAA GAAGAATCCTTTGGGAAACTGTGGAGATATAAATTTAGTACGACTAGGTCCAGAAAAGTCTATTAATACA GAGGTCTTAAAATTCAGTTTGGACAGCCAAGTCAACCATAGAATGAAAAAAGACTTGCCTTCTCATATTC AAGAAATGCTTAGAAGAAAAGAAATTCTAGATGCTCAACTTGATGAGCTTTCTCGTCAGCGAGCTCTGTG CCGAGGTGGGCGGGAGATGCAGAGGCAAGAATTAGATGAACACATTGCCATAGTCTCAAAAGAAAGGCAA GAACTTGCTTCGAAAATTAAAGAGGTTCAGGGACGCCCACAGAGAGCACAGAATACCATCATCTTGGAGT CCCATGTCATCTGCTGCACATTGAGCACTAGTGGTGGTTTATTGCTTGAGTCTGCTTTTCGAGGGCAAGG GGGTGTCCCCTTCAGTTGTGTCATCGTAGATGAGGCTGGGCAGTCTTGTGAAGTTGAGACACTTTCTCCA CTCATCCACCGCTGCAATAAACTTATCCTAGTAGGAGACCCCAAACAGCTCCCTCCCACAGTCATCTCTA TGAAAGCACAGGAGTATGGCTATGACCAGTCGATGATGGCCCGATTCTGCAAGCTGCTGGAAGAGAATGT GGAGCAGAACATGATTGGCAGGCTGCCGGTGTTACAGCTTACCATTCAGTACAGGATGCATCCAGACATA TGTCTTTTCCCTTCTAATTACGTTTATAACAAAAACCTGAAGACAAATAGATTGACTGAATCCATTCGAT GTTCATCAGAGTGGCCATTTCAGCCCTACCTCGTGTTTGATGTTGGAGATGGTTCAGAACGACGGGATAA TGACTCATATATAAATGTTCAAGAAATAAAGTTGGTGATGGAAATAATTAAACTTATTAAAGAGAAAAGA AAAGATATTTCCTTCCGAAATATTGGCATAATAACCCATTACAAGGCTCAGAAGACGATGATCCAGAAGG ATTTGGAGAAAGAATTTGATAAGAAAGGACCTGCAGAAGTGGACACAGTAGATGCCTTCCAGGGCCGGCA GAAAGACTGTATCATCGTTACCTGTGTCAGGGCAAGTGCTGTGCAAGGCTCAATAGGATTCCTGGCAAGT TTGCAGAGATTGAATGTCACCATTACACGAGCCAAGTATAGCCTCTTTATCCTTGGACATTTGAGGACTC TGATGGAAAACCAGCATTGGTATGAACTGATTCAGGATGCTCAGAAGCGTGGGGCCATTATTAAGACCAG TGACCCAAACTATAGACATGACGCAATGAAGATTCTGAAACTGAAGCCTGTGCTACAGAGGAGTCTGACC CATCCCCCAGCCACTGCCCCGGAGGCACCCAGACCCCAGGGTGGCTTGCCCAGCAACAGACTGGACAGTG GACTTGCCACAACATCTTTTGCTGCTTCTTTGTATCACACACCCTCTGATACTGTCACTTCAAAGGGACC TGAAAGGCCACTTCTTCAAGACCGACTTCGAGATCCACGACTACTCAGGAGATTGGATGCTGAAGCCAAG GGAACATTCCTGAAGGATCCACAGCCCGTTAGCCCCCAGCTCCCCGGGGTAGTTCATCTCTTGGGAGAGC CTGGCTTCCCTGTGGTTTTCCAGGACCTAGGTTTTGTTGTGCCGCCATCCACTGCCATTGTTGCTCCTCT GGGCAGCCACAGGTCACCTATGCAGGCTGAGCCACCACCTGCTCACCCTGCTGCTGCCGCCTCCACAAGT AAGAGGAAGTACAGTGACCCAGATGCTGGGCTCAGCCACAAAAGAGAACCCAGGGCCTTCAGTGGAGAGC AGGGGAGGCATGGCTCTGTGACTCATCACGTGCTGAGAAGCACTGACTGGGACAGGAGGAGGCTGGATGA CAGCAGTGCCAAGAGGAGACAATTTCTATAG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_198033 |
| Insert Size | 7941 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_198033.2, NP_932150.2 |
| RefSeq Size | 10970 bp |
| RefSeq ORF | 7941 bp |
| Locus ID | 269254 |
| UniProt ID | A2AKX3 |
| Cytogenetics | 2 B |
| Gene Summary | Probable RNA/DNA helicase involved in diverse aspects of RNA metabolism and genomic integrity. Plays a role in transcription regulation by its ability to modulate RNA Polymerase II (Pol II) binding to chromatin and through its interaction with proteins involved in transcription. Contributes to the mRNA splicing efficiency and splice site selection. Required for the resolution of R-loop RNA-DNA hybrid formation at G-rich pause sites located downstream of the poly(A) site, allowing XRN2 recruitment and XRN2-mediated degradation of the downstream cleaved RNA and hence efficient RNA polymerase II (RNAp II) transcription termination (By similarity). Required for the 3' transcriptional termination of PER1 and CRY2, thus playing an important role in the circadian rhythm regulation (PubMed:22767893). Involved in DNA double-strand breaks damage response generated by oxidative stress. In association with RRP45, targets the RNA exosome complex to sites of transcription-induced DNA damage (By similarity). Plays a role in the development and maturation of germ cells: essential for male meiosis, acting at the interface of transcription and meiotic recombination, and in the process of gene silencing during meiotic sex chromosome inactivation (MSCI) (PubMed:23593030). Plays a role in neurite outgrowth in hippocampal cells through FGF8-activated signaling pathways. Inhibits retinoic acid-induced apoptosis. May be involved in telomeric stability through the regulation of telomere repeat-containing RNA (TERRA) transcription (By similarity).[UniProtKB/Swiss-Prot Function] |
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