Hivep3 (NM_010657) Mouse Untagged Clone

CAT#: MC225284

Hivep3 (untagged) - Mouse human immunodeficiency virus type I enhancer binding protein 3 (Hivep3), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Hivep3
• Synonyms: 2900056N03Rik; A130075N07; AI848000; E030045D18Rik; KBP-1; KBP1; Krc; Rc; Schnurri-3; Shn3
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC225284 representing NM_010657
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGATCCTGACCAAAGCATCAAGGGCACCAAGAAGGCTGATGGAAGTCCCCGGAAGCGGCTGACCAAAG
  GAGAGGCCATTCAGACGAGTGTTTCTTCCAGTGCTCCATACCCAGGCAGCGGCACTACTGCTCCCTCAGA
  GAGTGCCACCCAGGAGCTCCTAGCCACGCAGCCTTTCTCAGGCCCCTCTCAGGAGAAAACGGGCCAGCAG
  CAGAAGCCTGCCCGGAGGCCTTCCATCGAGGCCTCGGTCCACATCTCTCAGCTTCCGCAGCACCCTCTGA
  CACCAGCATTCATGTCCCCGGGCAAGCCAGAGCATCTCCTCGAGGGGTCCACGTGGCAGCTGGTTGACCC
  CATGAGACCTGGACCCTCGGGCTCCTTTGTGGCCCCCGGGCTGCATCCGCAGAGCCAGCTCCTCCCATCC
  CATGCTTCTATCCTTCCTCCTGAGGAGCTGCCTGGCATCCCTAAGGTCTTTGTGCCTCGTCCCTCACAGG
  TCTCCCTGAAACCTGCAGAAGAGGCACACAAGAAAGAGAGGAAACCGCAGAAGCCAGGCAAGTATATATG
  TCAATACTGCAGCCGACCCTGCGCCAAGCCCAGTGTGCTCCAGAAACACATTCGCTCACACACAGGTGAG
  AGGCCCTACCCCTGCGGCCCCTGCGGCTTCTCCTTCAAGACCAAGAGTAACCTCTACAAGCACAGGAAGT
  CCCATGCCCACCGTATCAAAGCTGGCCTGGCCTCGGGCTCCAGCAGTGAGATGTACCCCCCTGGGCTGGA
  GATGGAGAGGATCCCCGGGGAAGAGTTTGAGGAACCCACCGAGGGAGAAAGCACAGACTCTGAGGAGGAA
  ACGGGTGCCGCATCAGGTCCCTCCACAGATGTTCTCCCCAAACCCAAGCACCCCCTGCTCTCAAGTAGTT
  TGTACAGCTCCGGGAGCCACGGTTCCAGCCAGGAACGCTGCTCCCTCTCCCAGTCAAGCACTGGCCCATC
  ACTAGAGGACCCCGCCCCATTTGCAGAAGCCTCATCGGAACATCCCCTGAGCCATAAACCGGAAGACACG
  CACACCATCAAGCAGAAGCTGGCACTCCGCCTGAGTGAGAGGAAGAAGCTGATCGAAGAGCAGACATTCC
  TGAGCCCAGGGAGCAAAGGCAGCACAGAGTCCGGGTACTTCTCACGCTCTGAGAGCGCTGAGCAGCAGGT
  CAGCCCCCCCAACACCAACGCAAAGTCCTACGCAGAGATCATCTTCGGCAAGTGTGGACGGATTGGGCAG
  CGGACCTCCATGCTGGCATCCACCTCTACCCAGCCCCTACTGCCTCTATCCTCGGAAGACAAGCCCAGCT
  TGGTACCTTTGTCTGTGCCCAGGACACAAGTGATCGAACATATCACCAAGCTCATCACCATCAATGAAGC
  CGTGGTGGACACCAGTGAGATCGACAGTGTGAAGCCCAGGAGGAGCTCTCTAACCAGGCGCAGCAGCGTG
  GAGTCCCCGAAGTCCAGCCTCTACCGGGACTCACTATCGTCCCATGGGGAGAAGACTAAGCAGGAGCAAT
  CACTGCTGAGCCTCCAGCACCCACCCAGCTCCACGCACCCTGTGCCTCTCCTGAGAAGTCACTCAATGCC
  TTCTGCCGCCTGCACCATCAGCACCCACCACCACACCTTCCGTGGTAGCTACTCCTTTGATGACCACGTC
  GCTGACCCCGAGGTCCCCAGCCGCAACACTCCCGTGTTTACCTCCCACCCACGGATGCTAAAGCGCCAGC
  CAGCCATTGAATTACCTTTGGGGGGTGAGTACAGTTCCGAGGAGCCTGGACCGAGCAGCAAGGACCCCAC
  CTCCAAGCCCTCCGATGAACCAGAACCCAAGGAAAGCGACCTTACCAAAAAGACCAAGAAGGGGTTCAAA
  ACAAAAGGCGCGAACTATGAATGTACCATCTGCGGTGCTCGGTACAAAAAGAGAGATAATTACGAAGCTC
  ATAAGAAGTACTACTGCTCTGAGCTCCAGATCACAAAAGCCCACTCTGTAGGTGCTCATGAAGTGGAAAA
  GACTCAGGCTGAGCCTGAGCCTTGGTCCCAGATGATGCATTATAAACTGGGGGCCACCTTGGAACTCACT
  CCGCTGAGAAAAAGACGGAAAGAAAAGAGCCTTGGAGATGAGGAAGAGCCACCTGCCTTTGGCAGCCCAG
  GCCCTTCAGAAACAGCTCATAACCGTCCCCTGGGGTCCACCAAGTCACCAGCAGAAGCAAGCAAATCAGC
  GCCCTCTCTAGAGGGACCCACGAGCTTCCAGCCCAGGACTCCCAAGCCAGGAGCTGGGTCAGAACCAGGG
  AAGGAGAGGAGAACAATGTCCAAAGAAATTTCCGTCATCCAGCACACCAGCTCCTTTGAGAAGTCTGACC
  CACCGGAGCAGCCCAGTGGCCTGGAGGAAGACAAGCCCCCGGCCCAGTTCTCATCCCCACCACCTGCCCC
  GCACGGACGCTCCGCTCACTCCCTGCAGCCAAGGTTGGTCCGGCAGCCCAACATTCAGGTTCCAGAGATC
  CTCGTGACAGAAGAACCGGACAGGCCTGACACAGAGCCTGAGCCGCCCCCCAAGGAGCCTGAGAAGACAG
  AAGAATTCCAGTGGCCCCAGCGCAGCCAGACACTGGCACAACTCCCAGCGGAGAAGCTGCCACCCAAGAA
  AAAGAGACTCCGCCTGGCTGAGATGGCGCAGTCCTCGGGGGAGTCCAGCTTTGAGTCCTCCGTGCCTCTG
  TCTCGAAGCCCAAGCCAGGAGAGCAGCATTTCTCTGAGTGGCTCCAGCCGCTCGGCTTCATTCGACAGGG
  AAGACCATGGAAAAGCTGAGGCCCCTGGACCCTTCTCAGACACACGCTCCAAAACCTTGGGCTCCCACAT
  GCTGACTGTCCCCAGCCACCACCCACATGCCCGAGAGATGAGACGGTCAGCCTCAGAGCAGAGCCCCAAT
  GTGCCCCATTCCTCACACATGACTGAGACCCGAAGCAAATCCTTTGACTACGGCAGCTTGTCCCCTACAG
  GACCATCCTTAGCAGTGCCTGCTGCTCCGCCACCCCCAGCCGCCCCGCCAGAAAGAAGAAAATGCTTTCT
  GGTACGTCAGGCCTCCCTGAACAGACCTCCAGAAGCCGAGCTGGAGGCTGTGCCCAAGGGAAAACAAGAG
  AGCAGTGAGGAGCCCGCAGCCAGCAAGCCTTCCACAAAAAGCTCTGTGCCCCAGATCTCTGTGGGCACTA
  CGCAAGGTGGGCCTTCAGGGGGCAAAAGCCAGATGCAGGACAGGCCCCCACTGGGATCCAGCCCACCCTA
  CACAGAAGCTCTGCAAGTGTTCCAACCTCTCGGCACCCAGCTGCCCCCTCCAGCCTCTCTCTTCTCCTTG
  CAACAGCTCTTGCCTCAGGAGCAAGAACAATCCTCTGAGTTCTTCCCCACACAAGCAATGGCCGGCCTCC
  TCTCCTCCCCATACTCCATGCCCCCGCTCCCACCTTCCTTGTTCCAAGCCCCACCACTTCCTCTACAGCC
  TACTGTGCTACACCCCAGCCAGCTCCATCTCCCCCAGCTCCTGCCTCACGCTGCAGATATCCCCTTCCAG
  CAGCCCCCTTCCTTTCTCCCCATGCCATGCCCTGCCCCTTCAACCCTCTCCGGATATTTCCTCCCTCTGC
  AATCCCAGTTTGCACTGCAGCTCCCTGGTGAAATAGAAAGCCACTTGCCCCCAGTCAAAACCAGCCTGCC
  CCCTCTGGCCACAGGACCTCCTGGCCCCTCCAGCAGCACAGAATACAGCAGTGACATCCAGCTGCCTCCT
  GTGACTCCCCAAGCCACCTCCCCAGCTCCCACATCAGCCCCACCACTGGCCCTTCCTGCCTGTCCAGATG
  CCATGGTGTCACTGGTTGTTCCTGTCCGAATCCAGACCCATATGCCATCCTATGGAAGTGCCATGTACAC
  CACTTTGTCTCAGATCTTGGTCACACAGTCTCCGGGTAGCCCAGCAAGCACGGCCCTTACCAAGTACGAG
  GAACCCTCCTCCAAAAGTATGACTGTTTGTGAGGCTGATGTATATGAGGCTGAGCCTGGGCCATCGAGCA
  TAAGCAAGGAACAAAACAGAGGTTACCAGACACCATATCTGAGAGTACCTGAAAGGAAAGGCACTTCACT
  GTCTTCTGAGGGTATCCTGAGCCTGGAGGGGTGCTCATCCACAGCCAGTGGAAGCAAGCGCGTCCTTTCC
  CCAGCTGGCAGTCTTGAACTTACCATGGAAACCCAGCAGCAGAAAAGGGTAAAGGAGGAAGAAGCTTCCA
  AGGCAGATGAAAAACTGGAGCTTGTGAGTACCTGTAGTGTCGTGCTGACAAGTACAGAGGATAGGAAGAA
  GACAGAGAAACCCCATGTGGGTGGCCAGGGCCGGAGCAGGAGGGAGGCAGAAACACTGTCCAGCTTGTCT
  TCAGATGTATCCGACCCAAAAGAACTTTCTCCCCTCTCTCATTCCACATTGTCCCATGGGACAGCCCCAG
  GCTCAGAAGCTTTGAAGGAATATGCCCAACCATCTAGCAAAGCTCACCGAAGAGGTCTGCCTCCAATGAG
  TGTAAAGAAAGAAGATCCAAAGGAACAGACTGACCTCCCTCCCCTGGCACCCCCTAGTTCTCTGCCTCTG
  TCAGATACTTCCCCTAAACCAGCCAAATTGCAAGAAGGTACGGACTCAAAGAAGGTACTGCAGTTCCCCA
  GCCTCCACACAACCACTAATGTCAGTTGGTGCTATTTAAACTACATTAAGCCAAATCACATCCAGCATGC
  AGATAGGAGGTCCTCTGTTTACGCTGGTTGGTGCATAAGTTTGTACAACCCCAACCTTCCAGGGGTTTCC
  ACTAAAGCTGCTTTGTCCCTCCTGCGATCTAAGCAGAAGGTGAGCAAAGAGACATATACCATGGCCACAG
  CTCCGCATCCTGAGGCAGGAAGGCTGGTTCCATCCAACTCCCGAAAGCCCCGCATGACAGAGGTGCACCT
  CCCGTCGCTGGTTTCCCCAGAGAGCCAGAAAGACCCAGCTAGAGTGGAAAAGGAAGAAAAGCAAGGGAAG
  GCGGAGGAAGGTACTCCCACTTCCAAGAGAGGCGAGCCGGCGAGGGTCAAGATCTTCGAAGGAGGGTACA
  AATCAAACGAAGAGTATATATATGTGCGAGGCCGCGGCCGAGGGAGATATGTTTGTGAGGAATGTGGAAT
  TCGCTGCAAGAAGCCCAGCATGCTGAAGAAACACATCCGCACCCACACTGACGTCCGGCCCTATGTGTGC
  AAGCACTGTCACTTTGCTTTTAAAACCAAAGGGAATCTGACTAAGCACATGAAGTCGAAAGCCCACAGCA
  AAAAGTGCCAAGAGACGGGGGTGCTGGAGGAGCTGGAAGCCGAAGAAGGAACCAGTGATGACCTGCACCA
  GGACTCAGAGGGGCAAGAGGGCGCCGAGGCTGTGGAGGAGCACCAGTTCTCAGACCTGGAGGACTCTGAC
  TCAGACTCAGACCTGGATGAAGATGAGGAGGAGGAAGAGGAGGAGGAAGAGAGCCAGGATGAGCTGTCTG
  GGCCATGCTCGGAGGCAGCTCCGCCTTGCCTGCCCCCCACACTACAGGAGAACTCCTCACCCGTTGAGGG
  CCCTCAGGCTCCAGATAGCACTTCTGACGAGGTCCCGCAAGGCAGCTCCATCTCAGAAGCCACGCATTTG
  ACCGCCAGCAGTTGTTCCACACCTAGCCGGGGTACCCAAGGCCTTCCCAGGCTGGGACTGGCCCCACTGG
  AGAAGGACATGAGCTCAGCCCCGAGTCCCAAGGCCACGTCCCCTAGGAGGCCGTGGTCCCCAAGCAAAGA
  AGCAGGCAGCCGCCCCTCACTCACTCGCAAACATTCACTCACCAAAAATGACTCGTCTCCCCAGCAATGT
  TCACCGGCCCGAGAAGCTCAGGCCTCAGTAACGAGCACACCTGGTCCCCAGATGGGCCCAGGAAGGGACC
  TGGGCCCTCACCTTTGTGGGTCTCCAAGACTGGAGCTGTCCTGTCTCACTCCCTACCCCATAGGAAGAGA
  AGCGCCCGCTGGACTCGAGCGTGCCACAGACACAGGCACCCCCAGATATTCACCCACCAGGAGATGGTCT
  CTGGGTCAGGCCGAGTCACCGCCACAGACAGTGCTGCCAGGGAAATGGGCCCTGGCTGGGCCCTGCAGCC
  CCTCAGCGGACAAGAGTGGCCTGGGCTTGGGGCCGGTTCCACGGGCCCTCCTCCAGCCCGTGCCTCTACC
  TCACACACTTCTCAGCAGAAGCCCTGAAACGTGCACCTCTGCATGGCGGAAGACTGAGTCCCGAAGTCCA
  TCAGCTGGCCCTGCTCCTCTCTTCCCCCGACCATTCTCCGCCCCTCATGACTTCCATGGCCACCTCCCTA
  GCCGAAGTGAGGAGAACCTCTTCAGCCACCTGCCTCTGCATTCCCAGCTCCTGAGCCGCGCCCCCTGCCC
  CCTCATTCCCATCGGTGGGATCCAGATGGTACAGGCCCGGCCAGGAGCCCAGCCCACCGTGCTTCCTGGA
  CCCTGCGCGGCCTGGGTCAGTGGCTTCTCAGGGGGCGGCAGTGACCTAACTGGGGCCCGAGAGGCCCAGG
  AGCGCAGCCGCTGGAGTCCCACAGAGAGCCCTTCAGCATCGGTGTCCCCTGTGGCCAAGGTCTCCAAGTT
  TACACTCTCGTCAGAGCTGGAAGAGGAAAGGACCGGCAGAGGCCCAGGAAGACCTCCTGACTGGGAACCT
  CACAGGGCTGAAGCCCCTCCAGGACCCATGGGCACACACAGCCCCTGCTCCCCACAGCTGCCCCAAGGCC
  ACCAGGTGGCACCTTCCTGGAGGGGCCTCTTGGGGTCACCACACACACTGGCCAACCTAAAGGCCTCAAG
  CTTCCCACCACTGGATCGCAGCAGCTCCATGGACTGCCTGGCAGAGACCTCCACTTACTCTCCACCCCGG
  AGCAGGAACCTCTCTGGAGAACCCAGGACCCGTCAAGGCTCCCCTGAGCTCTTAGGTAGAGGGGAGCTCA
  GGACACCTCTATTCCTGCCCAAGGGTAGTGGCCCCCCAAGCATCTAG
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_010657
• Insert Size: 7047 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_010657.3, NP_034787.2
• RefSeq Size: 9021 bp
• RefSeq ORF: 7047 bp
• Locus ID: 16656
• UniProt ID: A2A884
• Cytogenetics: 4 D2.1
• Gene Summary: Plays a role of transcription factor; binds to recognition signal sequences (Rss heptamer) for somatic recombination of immunoglobulin and T-cell receptor gene segments; Binds also to the kappa-B motif of gene such as S100A4, involved in cell progression and differentiation. Kappa-B motif is a gene regulatory element found in promoters and enhancers of genes involved in immunity, inflammation, and growth and that responds to viral antigens, mitogens, and cytokines. Involvement of HIVEP3 in cell growth is strengthened by the fact that its down-regulation promotes cell cycle progression with ultimate formation of multinucleated giant cells. Strongly inhibits TNF-alpha-induced NF-kappa-B activation; Interferes with nuclear factor NF-kappa-B by several mechanisms: as transcription factor, by competing for Kappa-B motif and by repressing transcription in the nucleus; through a non transcriptional process, by inhibiting nuclear translocation of RELA by association with TRAF2, an adapter molecule in the tumor necrosis factor signaling, which blocks the formation of IKK complex. Interaction with TRAF proteins inhibits both NF-Kappa-B-mediated and c-Jun N-terminal kinase/JNK-mediated responses that include apoptosis and proinflammatory cytokine gene expression. Positively regulates the expression of IL2 in T-cell. Essential regulator of adult bone formation.[UniProtKB/Swiss-Prot Function]