C2cd3 (NM_001017985) Mouse Untagged Clone

CAT#: MC225278

C2cd3 (untagged) - Mouse C2 calcium-dependent domain containing 3 (C2cd3), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: C2cd3
• Synonyms: AU020772
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC225278 representing NM_001017985
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGAAACAACGGAAAGGCCAAGGGCCTGGGGGCGGCCGTGGGCGCAAAAAGAGAGGTTTGAGTGACATTT
  CACCGTCTACAAGCCTGCCACCTCTGGTTGAAGGGCAGTTACGCTGCTTTCTCAAACTCACTATTAATAA
  GGTTGTATGGAAGATTGCGAAGCCTCCTACTTCTGTACTTGTCCGAGTAAGGTGGTGGGGAGAAACATCC
  GATGGAACCCTCTTTTGTCCCAGAGATGCATTACAGACTGAGCCAAAAGCTGTGAGAACAACTACCCGTT
  ACGGGATTCGCTGTGGTCCAAAGCAGTTTACCTCGTATCTGACAGATATGGCTGTGCTGGTGTTGGAAGT
  AATCACCAAGTTTGATCATCTTCCTGTTGGCAGAGTTCAGATCAGTGGACTTGCCCAGCTGTCTCCAACC
  CATCAGATCAATGGGTTTTTTACCATTGTTTCACCAGCATCGAAGAAACTTGGAGAACTTCAGGTCTCGC
  TTGCCCTGGAGCCTCTGTCAGAAACTTATGACAGCTACAAACCTCTTCCTGCCACTGAAGTGACAAAAAA
  TGTGCTTTTATCTGAGCGAGAACTCAGAGAGAATACTGAATCCAGCAACACCCAGTCTATGATCCCGTCA
  AGGTCTTGTAGGGGACCTGCCATCAAAATTGATGGGAAAGAATTAGCAGGCCACAGCAGCAGGTCAACCA
  CGCCAAGGGGAAAGGACCACTTGTACTTTGCAGAGAACTCCGATGCAGTAAAGGGTTCTTTGTGTGGACT
  ACAGCAGCACCTTAATCAAGGGACGAATGTAGAGACTATAACTCTGAGGGGCAAAGCCCCACAGAAGCAG
  CTGTCCCTCCTGAACAGCTCTGAGTTTCAGCCACAAATTAGTACAGTCGCCAAGAGTCACAGTGACTCAT
  GCATCCTGTCTTCAAACACCCCCCCTGCAAAGGACCTTCTTTCAGCTCTGTTAGAACAAGGCAATAAGCT
  GCGGAATGCCATGTTGATTTCTGCAATGAACTCCAACCCAGATACTAGTATGCTGCTTGACAAAGTCCCT
  CCTCCTATGACAGAAGCTATTCCCAGATCGTCAGCACTGAACTCATCTGAGAATCACTTTAAAGGCCACA
  GTGCAGACCACCTTCTCCCCTTGGCGGACACCGGAGCTATACAGCTGCTGTTGGGCAGTGCTGAATTGTC
  CCAAGGTCATTTCTGGAATGGATTAGGCTCTCCTCCAGATTCCCCGACTCCTGGGAGTGATGAGTACTGC
  AGCAGTGACCTGAATGATCCTCAGTATGACCAGAGTCTGCTGGAGAACTTGTTTTACACAGTGCCTAAAT
  CTGATGTCGGCACCAGTGAGCTCCCCAGTGAAGATGATGGAGTGGAACCTTCTAGAACAATGAACCAGTC
  CAAAGCCTCTGGCAGATCTAAGGTTGTAGAGTCAAAAGAGCAGAAGCAGAAGAGGGCAGCTGTCAAGAAA
  AGCAGAAACCCAATTGACCAGCAAGAGCTCTCAAGAACTCCAGGACATACCCCAGCGATGTCACTAAGTG
  TGGATAGACTGGCTCTTCTGGGTAGAGTACATTCGGTCAGAATCATCGTTGAAACCATGGGAGTCCCTCC
  AGATAGTCCCCATATGACACCAAGCAGGAAGAACTTTGCCGGGAAACCACCAAAGCCAACAGCAGCAAAA
  AAGCGCACTTTCTTTGTGGAGTATCACTTTCCTGTGGGCTTTTCCAAAAGTGGACTGGGAAAGACAGCTT
  TGATCACTGAGGTTGTTAGACTTGCCTCCAGTAAAATCACCGATGGAGTGGTGAAATTCCAGCAGCGATT
  TGTGTGTCCAGTAGAGTTTGGTGGCCCGATGATAGAGCACTGGTGGGATTCTAACCTCATCTTCCAAATT
  TATGCAAAGAAAACCCCACAGAAAAAGCCAGAAGTCATTGGATCTGCATCTCTCCCTTTGCGAGCTGTCA
  TTCAGTCAGAGCTGCTTTCTTTCAGTAGCCAGCTTCCAGTGCAACAGGAAAATGGTCTGTCTTCACTTGG
  CCCCCTAAAGGTCACCATGGAGCTTGTTTTAGGCCACAAGGATTTCACTGGAATCAGTGCTAAGTTAAGT
  AGCAGCACCCAACCTGCTCCAGTTTCTGCTGCTACAAGTTCAGATACGATACTACCAGAGACAGGCCAGG
  ATACCGCCTGTACCAGAAATCCACAGAGCTCAAATAAAATTCACGAGGAAACCACAAAGAAAACACAGAA
  TTTAGTGCTCCCCGACCAAGAGTCAGCAAACTCTGTAGCCTCAAACTCTTCAATCTTCATGGCTGTGCCA
  TCTTGCAATTTAGTCCATCAAATAAATGGCTCAAACAAAGAAAGCGGTTTGCTGTTACATGTGCTGTTGA
  TGGTGCCAGATGGGAAAGATTTTGTTTTTGGAGAACGGGAGAAACAACCATCATGCAATGTTTATTTGAA
  TTGCAAGCTTTTCAGCACAGAAGAAGTCACCAGATCTGTCGTCTCGTGGGGCACAGCACAGCCTGTCTTT
  AATTTTTCTCAGGTGATCCCTGTCTCTCTGACTTCCAAATGCCTGGAGAGACTTAAGAACAATGTGATGA
  TAATTGAAACTTGGAACAAGGTGCGGAGCCCAGGACAGGACAAGCTGCTCGGGCTGGTGAAACTGCCACT
  CCATCAGTTTTACATGTCATTCAAAGACCCCAAGATTTCTCGCCTGCTGCTTGATGCCAGGTACCCAGTT
  GTTGCTGTTGACAGCTATATGCCTGTGATTGATGTGTTCTCGGGCCACCAAAATGGGAGTCTTCGAGTCT
  TTTTAGCCATGGGTTCTTCAGCTCAGATAATGATGCTGCAAAGATTAAAGAATGAAGAAGGAACACTCCC
  TCCCTTCAGTCCTAGGCCAGCCCATTTCCTGGACCAGCCACCTGTAGCATCTGTTGCTATGCCAGAAAAA
  CAAGGAACCCGGTTGATGGAGCACCACTTTGAGTTCTGTGTGGCGATGGTTAAAGGGCTCATGCCCCTTC
  AGGCAACAGTCTGGGGAGAAGCAGATTGCTACGTCCAGTACTACTTTCCATTTCAAGACTCCCAACCCAG
  TGTGCTCCAAGGACCCGACTTCCTTGAAAATGGAATTACTCTGAAGCCCTTTAGAACTTCAACCACACTG
  TGTGTCCCAGATCCCGTCTTTAATAGTGAACACCATCACTCTCTCCTGTTGCCGACTGACGTTCCAGTGC
  AAAGGCTCCTGCTGAGTGCCTTCTCCTCCCAGGGGCTGGTGCCTGGAGGAGGCGTCCAGTTTGAAGTCTG
  GTGCAGATACTATTATCCTAACGTAAGGGACCAGATGGTTGCCAAAGGAACCTTGCCATTATCAAGGGTC
  TGTGCCATGGTAACCATGCAGTACCGTGAAGATGTGGGAATGCAGAGCTTTAATCTCCCATTAACCTCCA
  GACTTGAGCACAGCAAAGAATTAAAGAACCAGTCATCAGGTTTCCTGGATGTGGGTTTGAGGTACCGGCG
  TAGCCCAAGAACAGCAGAGGGAATTCTTGCTGCCCGAGCTGTCTCCATCTCAGTCCATATTATCAGAGCC
  TGTGGTCTTCAGGCAGCAGCCAAGGCGTTGGCTGAGCAGGAACCCGCTTTACAGTTTAGCGCCACCGTTG
  GAGTCAATGCTTCTGTCACCGCCCATCTCTCATTTCTGCCCAAGGGGGAGCAGCGCCAAACCCGCCCTGT
  GGCCTGCTCCTTCTGCCCTGAGTTCTCCCACCACATTGAGTTCCCGTGTAACCTGGTGACTCAGCACTGT
  AGTGGAGAAGCCTGCTTCCTGGCAGAGCTGTTGGAGTTTGCAGAAATTATTTTTGCTATCTATCATGAAA
  ATACCAAATCAGTCAGTGATATAACCAGTATCCAGTCGTGCAAGGATTATCTGCTTGGAATAGTAAAGGT
  TCCAACGAAAGATCTGCTGGTCAAAAGATCTGGGATCACAGGATGGTATCCTGTCATTTTACCAGAAGAC
  AAAGGCCTGCCTCAGGACCTGGACTTGATGCAGAAGATTGTAGGAGGCTTGGAGCTTTCTGTTTCCTTCG
  CACATCCGGGAGATAGAGAGAGGGTACTGGAAGCTGCTGAGCTGCTGGGCTGGAGCTTTGAGAGCATCCC
  AAAGGATCTTGTCAAGAAAGAAGAAGAGGTGCCAGCCACTGTCACCATCTCTACCCCAAGGCTCTGGCTT
  CCTATCCACTGTGTGCTGCTTGCTGGTCATATGAACATTCATAAGAATACATATTGCTACCTTCGCTACA
  AGCTGTACAATCAAGAAGCCTTTTGGACTCCTCTCAGGAAACCTAAGGAGTCTACAAACAAAAACCAGGT
  CCTGATTACTTTCAAGGCATCCAAAAGAGCAGAAGTCACTAGGAGCCAGTCCCTGCTTTGGTACTTCAGG
  GAAGAGAAGTTAGAGATCCAAGTGTGGCGAGCCTATGGCAACGACAATTTAGAGAGGCCACACCAGACTG
  ACAGCTGGATTGGCTCAGCCTATGTAGACCTGTCCAGACTTGGGGAAAAATCTCCAAGGACACTGACTAT
  CAGTGGGGTGTATCCCCTGTTTGGAAGAAATGCTTCCGACCTCTCTGGAGCTGCTCTGCGCATTCATGTG
  CTTCTTTCCCCGCTTTCCCCACACACTGAACCTGCTCGGGAGCTGGACTCCATGGACTGCAGCAGCCACA
  GTGAGTCTGAGCAGCACCCCAGAAAGAGCGATGCGCTCCAGCTCTCTCCACCCCATGTGCTCCAGACGTC
  TCCCACCTCCACCCAGGTCCACGGCAACAGTGCTGCAGCCCAAGTGTGCCCCGCCCAGGAGGGCCCTCCT
  GAGTTGGCTGGGACTTTTGCAGTCAGCATCCTGGTAGAGAGAGCCATGCATCTGAGCTTGAAAGGGAGCC
  CCTTGACAGACCGGAAAGTATCTGTACCCAGTTGCTGTGTATCCTTTGCCACAGCCACTGAGCTGTCTCC
  TGTCTACACTCACGTGGTTGAAAACACGGATTCCCCCATCTGGGGTTTTCACCAGCAGGCAAGGCTTTCA
  AAAGAGCTGCTTCTGGACCCACATCAAACCCTGGTCTTCAAAGTGTGGCATAAAGGAGATGAAGAGAGGG
  TGGTTGGCTTTGCCTCGGTGGACCTCTCCCCACTACTGTCTGGCTTTCAGTTTATCTGTGGCTGGTACAA
  TATTACAGACTTCAGTGGAGAGTGCCAAGGGCAAATCAAAGTTGCTATTTCACCTATGGAGAGCCTGATG
  CACCTAAAAGAAGAAAGACAAGCAAGACGTGGGATAGATACTCCAGGAGCACTGATTCCATTGTTTAGCG
  CCCTTTCCTTCCCTGCCTCTGCTGGATGCGATGCATTCCCTAGGCCCATTGCAAGGCACGTCGAAGGCCA
  GCTTGCTCACACATCTCCAAAGGAGGACGGTCTCTCCTCTCCTGCAAGAAATGGTGCCATCAGAAGCCAG
  GCCGCACGCCATGAAGAGCATGTGCAGAACATCCGCCGCTTTCACGAGTCCCTGCAGCACGGGGAGGCAG
  TCCTGACAAGTGATGAGAAGCTGACCACAGCGCCTTCGTCCTCCCACACCTCCATCCTGACTTCTCTCAG
  GAAGAATCTGAGTGAGCTAGATGAGATCCAGAAGTACTTCAGCCAGAAGCTCAGCAAGCCCTTCCTGCCC
  TTCTCCTCTCAGAGCTCGCCTGCTGTCTCACAGAGCCAGGAGAGCCAGAGGGACCCTGTGGCTGCAGGAA
  CCGGCCGCCAGGACCCCGAGAACCAGTGCATCCTGGAGAAGTCCAATCACCTGGTGTCGCAAGTCAGCTC
  CTTGATCTCAGATCTGCAGACTCTCACCAGAGGTTCACAAGCAGCTTTGACTTCTCAGCAAGCCAGGAGT
  AGAAGCAGAGCAGTCACCACCATCCCAGATGCTCAGGGCACCGAAGCTGCTGGAGAAGGAAGCACCACAC
  TGGAGGAGCCTTTGGCAGGAGCTATAGAGGCGAGCACAGATTCCCTGCCTCCCCCTGTTGAAGAGCCTTC
  CAAGGGAGGAGGGATGCTCCATGAGTCGCTGGAGCAGACGATGCCCATCACGAGGGTGCAGAGCATCGAT
  GACACGGAGGTGGGCCCAGACTACAGTGATGAAGACTATGAGGAAGACATTATTGAGCCCAGGACCCTAA
  ATGAAATAACCACAGTGACAGACAGAACCAGCCCCTGGTCCAGTTTCATGTCAGACATGAGTGAGGTCCT
  TAGCCCTCAGCCCACTGAGGTACAAAGGGAAGGCCCCTCATGTCCCCCAGAACCTTTCCCCAGAGAGGAG
  CTGAAGGTCAAAAGTAGCCCGCAAAAGGCAGTCAGCCCCCAGCCTGCACAGGGCTCCCCTAGCCAAAGTG
  GTGTTTGTGAGGGTGGAGCCTATAAGATCGAGGTTGAAGACCTTGCCTCAGCCAAGCCTCAGCCTGTCCC
  AAGCCTAACATTCTCAGAAGCCCAAGAGGGCAGCGATTCTGTTGGATGGCGTGCATCACAGATAAATCAG
  GTCAGGAAGCCCATGCCAGAGATGCTGGCTGAGAGTGAGGCTTTCTCCAGTGAGTTCAGTGACTCTTCTG
  AAAGCTTTGAGACGTTTCCTCTACACCTACCCTCCCAAAGCAAAAGAGAAGACTACAAGGACTCCCCTGC
  TGTGAGGCAGAAGCAGGTACCAACTGGATCAGAGGTGTCCACAAGGCAGACGCTCCTTCTCCCAGAACCT
  GTTGTGGTGCCCAACTTCTTTTTGCCTCCCCAACAACTGGAGGCCTCTCTCCGCATGATCTCACACTCTC
  CAGGTTTGCCACCAGCAGCCACAACTGACCAGGACAAGAGTGAAGCCACCAGGGGAGCCCTTGCCCAGAG
  GCCTTGTCGCCCCAGACCTTACTCCATCCCTCCCAACCTTCCTGAGGAAGAGACTCGCAGGATTGCACGG
  ATATTTTCTTCCCAGTATTCCAAAAAGACTGAGGAAACCTGA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_001017985
• Insert Size: 6972 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001017985.2, NP_001017985.2
• RefSeq Size: 7813 bp
• RefSeq ORF: 6972 bp
• Locus ID: 277939
• UniProt ID: Q52KB6
• Cytogenetics: 7 E2
• Gene Summary: Component of the centrioles that acts as a positive regulator of centriole elongation (PubMed:24997988). Promotes assembly of centriolar distal appendage, a structure at the distal end of the mother centriole that acts as an anchor of the cilium, and is required for recruitment of centriolar distal appendages proteins CEP83, SCLT1, CEP89, FBF1 and CEP164. Not required for centriolar satellite integrity or RAB8 activation (PubMed:24469809). Required for primary cilium formation. Required for sonic hedgehog/SHH signaling and for proteolytic processing of GLI3 (PubMed:19004860).[UniProtKB/Swiss-Prot Function]