Shank1 (NM_001034115) Mouse Untagged Clone

CAT#: MC225206

Shank1 (untagged) - Mouse SH3/ankyrin domain gene 1 (Shank1), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Shank1
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC225206 representing NM_001034115
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGACCCACAGCCCCGCGACAAGCGAGGACGAGGAAAGACACAGTGCCAGCGAGTGTCCCGAGGGGGGCT
  CAGAATCGGACAGCTCCCCAGACGGGCCAGGAAGAGGCCCCCAGGGGACTCGGGGCCGAGGCAGCGGAGC
  ACCTGGTAACCTGGCCTCTACCCGAGGCCTCCAGGGACGCTCCATGTCTGTCCCTGACGACGCCCACTTC
  AGCATGATGGTTTTCAGGATTGGCATCCCTGACTTGCATCAGACGAAATGCCTACGCTTCAACCCAGATG
  CCACCATCTGGACAGCCAAACAGCAAGTACTCTGTGCCCTGAGCGAGAGTCTACAGGACGTGCTGAACTA
  TGGACTGTTCCAGCCAGCCACCTCAGGCCGGGATGCCAACTTCTTGGAGGAGGAGAGGCTTCTAAGAGAG
  TACCCTCAGTCCTTTGAGAAAGGGGTACCCTACCTGGAGTTCCGCTACAAGACCCGAGTCTACAAACAGA
  CCAACCTGGATGAGAAACAGCTGGCCAAGCTGCACACAAAGACTGGGTTGAAGAAGTTCCTGGAATATGT
  GCAGCTTGGGACGTCTGACAAGGTGGCAAGGCTGCTGGACAAGGGGCTGGACCCCAACTACCACGACTCA
  GATTCAGGAGAGACACCTTTGACCCTGGCGGCCCAGACTGAAGGCTCAGTAGAGGTGATTCGGACGCTGT
  GCCTGGGCGGGGCGCATATAGACTTCAGGGCCCGGGATGGCATGACAGCGCTTCACAAAGCTGCATGTGC
  CCGGCACTGCCTGGCGCTCACGGCACTTCTGGACCTTGGGGGCTCCCCCAACTACAAGGACCGACGAGGG
  CTGACCCCCCTGTTCCACACAGCTATGGTGGGGGGAGACCCCCGCTGCTGCGAGCTACTTCTGTACAACA
  GGGCCCAGCTGGGCATTGCAGATGAGAACGGCTGGCAGGAAATCCATCAGGCCTGCCAACGAGGGCACTC
  TCAGCACCTGGAACACCTGCTCTTCTATGGGGCTGAGCCTGGAGCCCAGAATGCCTCAGGAAACACGGCC
  CTGCACATCTGTGCTCTCTACAACAAGGAGACCTGTGCCAGGATCCTCCTTTATCGTGGAGCAAACAAGG
  ATGTGAAAAATAACAATGGACAGACACCCTTCCAGGTGGCTGTGATTGCTGGGAATTTTGAGCTGGGGGA
  ACTGATTCGTAACCATCGGGAACAGGATGTGGTACCTTTCCAGGAGTCCCCCAAGTATGCAGCCCGGCGT
  CGGGGACCCCCAGGCGCAGGGCTGACTGTACCCCCAGCGCTGCTGCGAGCTAACAGTGACACGAGCATGG
  CGCTGCCTGATTGGATGGTGTTTTCGGCCCCAGGGGCCTCATCCTCTGGGACCCCTGGCCCTACCTCAGG
  ATCCCAGGGCCAGTCACAGCCCTCGGCCCCCAGCACCAAACTCAGTAGTGGGACCCTCAGAAGTGCCAGC
  AGTCCCCGAGGAGCCCGGGCACGCTCCCCGTCCCGGGGGAGACATCCTGAAGACGCCAAGAGACAACCTC
  GAGGCCGGCCCAGCTCCAGCGGGACACCCCGAGATGGGCCGGCTGGGGGAACTGGGGGCTCAGGGGGCCC
  TGGGGGCTCCCTGGGCAGCAGAGGCAGACGTAGGAAGCTCTATTCAGCGGTACCCGGTCGCTCCTTCATG
  GCGGTGAAGTCCTACCAGGCGCAAGGCGAGGGGGAGATCTCTCTGAGTAAAGGCGAAAAGATCAAAGTGC
  TCAGCATCGGGGAAGGAGGCTTCTGGGAAGGCCAGGTCAAAGGTCGAGTTGGCTGGTTCCCTTCTGACTG
  CCTAGAAGAGGTGGCAAACCGTTCCCAGGAGGGAAGACAAGAAAGCCGAAGTGACAAGGCAAAGAGACTC
  TTCAGGCATTACACAGTGGGCTCCTATGACAGCTTCGATGCCCCAAGTCTGATCGATGGGATTGACTCAG
  GGAGTGATTACATCATCAAGGAGAAGACAGTCTTACTGCAGAAGAAGGACAGTGAGGGGTTCGGGTTCGT
  GCTCCGGGGGGCCAAGGCGCAGACCCCCATCGAGGAATTCACCCCCACCCCGGCCTTCCCGGCGCTGCAG
  TACCTCGAGTCTGTGGACGAGGGTGGCGTGGCATGGCGGGCTGGACTACGAATGGGAGACTTCCTCATCG
  AGGTGAACGGACAGAATGTAGTGAAGGTTGGCCACCGTCAGGTGGTCAACATGATCCGACAGGGAGGCAA
  CACACTGATGGTCAAGGTGGTGATGGTGACCAGACACCCAGACATGGATGAGGCTGTCCACAAGAAAGCA
  TCCCAGCAGGCTAAGCGGCTCCCGCCCCCAGCCATCTCCCTGCGTTCCAAGTCTATGACCTCAGAGCTGG
  AGGAAATGGTCTCCCCCTGGAAGAAGAAAATTGAATACGAACAACAGCCTGCAGCAGTGCCCAGCATGGA
  GAAAAAGCGGACTGTGTATCAGATGGCACTCAACAAACTGGATGAGATCTTGGCTGCAGCTCAGCAGACC
  ATCAGTGCAAGTGAGAGTCCTGGGCCTGGCGGCCTCGCATCCCTGGGCAAGCACCGACCCAAAGGATTCT
  TTGCCACTGAGTCGAGCTTTGATCCTCACCACCGCTCCCAGCCAAGTTATGACCGGCCTTCTTTCCTGCC
  TCCCGGACCTGGCCTTATGCTCCGGCAGAAATCTATCGGGGCTGCGGAAGATGACAGACCCTACCTAGCA
  CCCCCAGCCATGAAATTCAGTCGTAGCCTGTCAGTCCCGGGTTCAGAGGACATACCCCCACCACCCACTA
  CATCCCCACCAGAGCCGCCCTATAGCACACCTCCGGCCCCCTCCTCTTCCGGCCGCCTCACTCCCTCGCC
  TCGGGGAGGGCCCTTTAACCCTGGTTCCGGGGGTCCCCTTCCCGCCTCCTCACCTTCATCTTTCGATGGG
  CCATCTCCTCCTGACCCCCGTAGTGGGGGCCGAGAGAAGAGCCTATATCACAGTGGCGCCCTACCCCCTG
  CCCACCACCACCCACCTCATCACCACCATCATCACGCCCCACCTCCTCAGCCCCACCATCACCATGCGCA
  TCCTCCCCACCCACCGGAGATGGAGACAGGAGGTTCCCCCGACGATCCCCCACCTCGATTGGCTCTGGGA
  CCCCAGCCCAGCCTTCGAGGCTGGCGAGGTGGAGGACCCAGCCCGACCTCGGGGGCCCCATCACCTTCCC
  ACCACAGTAGCAGCGGAGGCAGTAGCGGTCCTGCTCAGGCTCCCGCCCTGCGCTACTTCCAGCTGCCCCC
  GAGGGCGGCCAGTGCGGCTATGTACGTACCAGCCCGCTCCGGCCGCGGTCGCAAAGGCCCGCTGGTCAAG
  CAGACCAAAGTGGAAGGCGAGCCCCAAAAGGGCAGCCTCCCTCCCGCGTCCTCTCCAACATCCCCGGCGT
  TGCCTCGGTCCGAACCACCTCCGGCCGGGCCGTCGGAGAAAAATTCCATCCCTATCCCTACCATCATCAT
  CAAAGCCCCATCTACCAGTAGCAGCGGCCGCAGTAGCCAGGGAAGCAGCACAGAGGCTGAGCCCCCCACC
  CAGCCCGACGGCGCGGGCGGCGGAGGATCCTCGCCTAGCCCTGCACCTGCCACGTCCCCTGTACCGCCGT
  CCCCGTCGCCCGTGCCCACCCCTGCGTCACCCAGCGGCCCGGCCACCCTGGATTTCACTAGCCAGTTTGG
  AGCAGCCCTAGTGGGCGCGGCGCGGAGGGAGGGAGGCTGGCAAAACGAAGCCCGGCGGCGGTCCACGCTA
  TTCCTGTCCACCGACGCAGGAGATGAGGATGGAGGCGACAGCGGGCTGGGCCCGGGGGCGCCCCCGGGTC
  CCCGGCTGCGCCATTCCAAATCCATTGATGAAGGCATGTTCTCCGCCGAGCCGTACCTCCGGCTGGAGTC
  GGGGGGCAGCAGCGGGGGCTACGGGGCATACGCAGCGGGCAGCCGAGCCTACGGGGGCAGCGGGAGCAGC
  AGCGCCTTCACCAGCTTCCTCCCCCCGCGGCCCCTGGTGCATCCGCTGACCGGCAAAGCCTTGGATCCCG
  CCTCTCCGCTGGGGCTGGCCTTGGCCGCCCGGGAGCGGGCCTTGAAGGAGTCCTCGGAGGGCGGGGTCAC
  CCCTCAGCCGCCCCCGAGACCTCCATCACCACGCTACGACGCCCCACCGCCCACCCTTCACCACCACTCG
  CCCCATTCACCCCATTCGCCACATGCGCGTCATGAGCCAGTGTTGCGCCTCTGGGGAGACCCGGCGCGCC
  GGGAGCTGGGGTACCGGGCAGGCCTAGGGAGTCAGGAGAAGGCCCTTACCGCTAGTCCACCTGCAGCTCG
  CCGCTCGCTACTGCACCGTCTTCCCCCGACGGCTCCCGGGGTCGGGCCGCTCCTGCTTCAACTGGGGCCG
  GAGCCCCCAACTCCCCATCCTGGGGTGAGCAAGGCCTGGCGCACAGCAGCCCCCGAGGAGCCAGAGCGGC
  TGCCTCTGCATGTGCGATTCCTTGAAAATTGCCAGGCCCGGCCTCCTCCAGCTGGCACGAGAGGGTCCTC
  CACTGAAGATGGGCCTGGGGTTCCGCCTCCCAGCCCTCGCAGAGTCTTGCCAACCTCTCCCACTTCCCCG
  CGAGGCAACGAGGAGAACGGCCTTCCGCTACTGGTCCTGCCACCGCCAGCCCCTTCGGTGGATGTGGACG
  ACGGCGAGTTCTTGTTTGCGGAGCCGCTGCCTCCACCCCTGGAGTTTTCCAATAGCTTCGAAAAGCCAGA
  GTCGCCTCTCACACCCGGGCCTCCCCACCCGCTGCCTGACCCTCCCTCCCCAGCTACCCCTCTACCCGCA
  GCCCCACCTCCGGCTGTGGCCGCCGCCCCTCCCACCTTGGACTCCACAGCATCCAGCCTGACCTCTTATG
  ACAGCGAAGTGGCCACGTTGACCCAGGGGGCTCCCGCGGCTCCTGGGGACCCTCCTGCTCCAGGCCCTCC
  GGCCCCGGCAGCTCCAGCTCCTCCAGCACCGCAGCCAGGCCCCGACCCTCCACCTGGCACAGATTCTGGA
  ATTGAGGAGGTGGACAGTCGGAGCAGCAGCGATCACCCGCTGGAGACCATCAGCAGTGCATCCACACTCA
  GCAGCTTGTCCGCCGAAGGAGGAGGCAACACAGGGGGCGTGGCTGGGGGCGGGGCCGGGGTGGCCAGCGG
  GACGGAGCTCCTGGACACCTACGTTGCCTACCTGGATGGCCAGGCCTTCGGGGGCAGTGGGACTCCTGGC
  CCACCATATCCCCCTCAGCTCATGACTCCTTCTAAGCTCCGGGGCAGGGCGCTTGGGACTAGTGGAAATT
  TGAGACCTGGTCCCAGTGGGGGACTTCGAGATCCTGTCACCCCCACCAGCCCCACCGTCTCTGTGACAGG
  AGCTGGAACAGATGGGCTACTGGCCTTGAGTGCTTGTTCTGGACCCTCAACGGCAGGTGTGGCAGGGGGT
  CCCGTGGCGGTTGAGCCAGAAGTCCCGCCTGTACCTTTGCCCACTGCCTCATCCCTGCCTCGGAAGCTAC
  TACCATGGGAGGAGGGTCCGGGACCACCACCACCACCCCTGCCAGGGCCCCTGTCCCAGCCTCAGGCCTC
  TGCCTTGGCCACGGTCAAAGCCAGCATCATCAGCGAACTCAGCTCCAAGCTCCAGCAGTTTGGTGGGGCC
  TCTACCGCGGGAGGAGCTCTGCCTTGGGCTCGGGGAGGCAGCGGGGGCAGCACAGACAGCCACCACGGAG
  GAGCCAGTTACATCCCAGAGAGGACCTCCTCCCTGCAGCGGCAGAGGCTCTCCGAAGACTCCCAGACCTC
  TCTCCTCTCCAAACCCAGCAGCAGCATCTTTCAGAACTGGCCTAAACCCCCTCTGCCACCACTCCCCACC
  GGATCTGGGGTCTCCTCTTCAACAGCTGCAGCCCCAGGAGCTACATCCCCTTCAGCCTCATCTGCCTCAG
  CTTCCACCAGACACCTGCAGGGTGTGGAATTTGAGATGCGGCCTCCGCTGCTCCGCCGGGCACCCAGCCC
  CTCGCTGCTGCCTGCCTCGGATCACAAGGTCAGCCCAGCGCCCAGGCCCTCTTCTTTGCCCATCCTGCCT
  TCAGGACCCCTCTACCCGGGCCTCTTCGACATCCGTAGCTCTCCGACCGGAGGGGCAGGAGGCTCGGCTG
  ACCCCTTCGCTCCCGTCTTTGTGCCACCACACCCCGGGATATCTGGGGGTCTTGGAGGAGCCTTGTCTGG
  GGCCTCTCGCTCCCTATCACCCACCCGCCTGCTCTCGCTGCCCCCGGACAAGCCGTTCGGCGCCAAGCCT
  CTAGGGTTCTGGACCAAGTTTGACGTCGCTGATTGGCTGGAGTGGCTGGGCTTATCAGAGCATCGAGCCC
  AGTTCCTGGACCACGAGATTGATGGCTCCCATCTGCCCGCCTTGACCAAGGAGGACTATGTGGACCTGGG
  CGTGACCAGGGTGGGCCACCGTATGAACATTGACCGGGCTCTCAAATTTTTCCTGGAGAGGTGA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_001034115
• Insert Size: 6504 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001034115.1, NP_001029287.1
• RefSeq Size: 7596 bp
• RefSeq ORF: 6504 bp
• Locus ID: 243961
• UniProt ID: D3YZU1
• Cytogenetics: 7 B3
• Gene Summary: Seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors, and the actin-based cytoskeleton. Plays a role in the structural and functional organization of the dendritic spine and synaptic junction. Overexpression promotes maturation of dendritic spines and the enlargement of spine heads via its ability to recruit Homer to postsynaptic sites, and enhances presynaptic function (By similarity).[UniProtKB/Swiss-Prot Function]