Rp1 (NM_011283) Mouse Untagged Clone

CAT#: MC225165

Rp1 (untagged) - Mouse retinitis pigmentosa 1 (human) (Rp1), transcript variant 1, (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Rp1
• Synonyms: Dcdc3; Gm38717; mG145; O; Orp1; Rp; Rp1h
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC225165 representing NM_011283
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGAGTGACACACCTTCTACTAGTTTCTCCATGATTCATCTGACTTCTGAAGGTCAAGTTCCTTCCCCTC
  GCCATTCAAATATCACTCATCCTGTAGTGGCTAAACGCATCAGTTTCTATAAGAGTGGAGACCCACAGTT
  TGGCGGCGTTCGGGTGGTGGTCAACCCTCGTTCCTTTAAGACTTTTGACGCTCTGCTGGACAGTTTATCC
  AGGAAGGTACCCCTGCCCTTTGGGGTAAGGAACATCAGCACGCCCCGTGGACGACACAGCATCACCAGGC
  TGGAGGAGCTAGAGGACGGCAAGTCTTATGTGTGCTCCCACAATAAGAAGGTGCTGCCAGTTGACCTGGA
  CAAGGCCCGCAGGCGCCCTCGGCCCTGGCTGAGTAGTCGCTCCATAAGCACGCATGTGCAGCTCTGTCCT
  GCAACTGCCAATATGTCCACCATGGCACCTGGCATGCTCCGTGCCCCAAGGAGGCTCGTGGTCTTCCGGA
  ATGGTGACCCGAAGAATAAGCATGTGGTCCTTCTTAGCCGGAGGATCACTCAGAGCTTCGAAGCCTTTCT
  GCAGTACCTGACACAGGTTATGCAGTGTCCTGTGGCCAAGCTGTATGCCACAGATGGAAGAAAAGTTCCT
  AGTCTCCAGGCAGTGATACTCAGCTCTGGAGCTGTGGTGGCAGCTGGAAGGGAGCCATTTAAACCAGGAA
  ATTACGACATACAAAAGTACTTGCTTCCTGCCAAGTTACCAGGAATCTCTCATCGTGTGCACCAGAAGGG
  AAAAGCCAAGATAGAAAAAAGAAAGATGAGCACACATATGCCTTCAGACCTAAGACCCCAGACTGATTCC
  CTGATCTCGGAGAAAACATATGATTGCTTTTCAGATTTTTCTGTAGCCCCTGAGAATTACTTGGCCTTAG
  AAACACATGAGTCTCAGTCTCTATCAACTTATCCTTCTGAAGATGATGTTGAGAAATCGATTGTTTTTAA
  TCAAGATGGTACGATGACGGTCGTGATGAAAGTTCGATTCAAGATAAAAGAAGAAGAAACTGTTAAGTGG
  ACAACAACTGTCAATAGAGCTGGTCTTTCTAATAATGATGAAAAGAATAAGAAAAGTAGTTATCCTGGAA
  AAACAGATTATGGACCATCTAGTTTAAAGCTTGAAGCATGTTCGTTGCCTGAAGACATCGTAGATACCAC
  TCAGCAGGGCAGTTTGACAGAGGAAGAAAATACTCAAATGACAGAGCAGCAGGCTCTGTCATGTAGCTCT
  GCTAGTTGGGAGAATGCCTCTATGGAGACAGACATTCAGGAAAGCCAGAAACAAGTGAAACACTTTTATA
  GACCCCCAACTCCTGGACCAAGGAGAATGAGACAAAAGAAATCTGTGATAGGGACTGTCACAGTAGTATC
  TGAAACAGAGGTTCAAGAAAAGCAGTTTTCCTATAGTGAAGAAAGAAAGGGTGGAGAAAAATCTGAGTAT
  CATATGTTTACACATTCTTGCAGTAAAATGTCATCAGTATCTAATAAACTTGTTCAGATCGGTAGCGATA
  ATGAGATGGAGTCAGCATTAGAAAGAACAAGGGAAAGTGGATCACTCAAGTCACAGGCCATAAATGCTGG
  TGCTATTGAAATTACAAGTCAGAAGGTCTTAAAGATGTGCCACAACAATGCTTTACCGTCAACTGCACCA
  GAGAACTCAGTCGTGGAAGAAGGCACAGACAACAGTGCAGTATCAGGCACAGCCACTATCAAGCACTTCA
  GAACTTGTGGTAATGCCAATGACAGCTTCAGTTCTATCACAGCAGATTCAACTCCTACCTCAGTTAACAA
  TTATTCAAATGACAGAAATATTTCTGAGCTTCCTTCTGTAGGATCTCCTGTACTCACCATGAGACTTGTT
  AATGAATTTGCTCATTGTGGTTTAACAGAAAAACCAGAAAACAGAAAGAAGGTTTTATCTTCTTCTGCTA
  GCAAGAAGAAGAAAAAGAAATCTCAGCAGCGAATGATAACTTCCAATGATAAGAAAAAAGTGATTGAAAC
  CAAAGGACCCCCAAATATAGCTGGGAAGATACCCAGAGCTGGAACAACTGCACAGGAAAGACTATTGCAA
  GAATCAGACTGTCCTGATAAAGGAGGAAGAGTTTGTGAGCAGGGCCTTAATATAAGTCCTATGGCAATTG
  AATCAAATAATTTTTTTCCCAAAAGTAATCCCACATTTTCTAAGAATTTCTATAAAAATAAATTAAATAC
  TTTTCAAAATCCTAAGACTCAAAAACTTTTGGCCAAAAGAAAATCAAGGCCACGAAAGATTGTAAGCACA
  GAAAGACTCAGAAAACAAGAGATTGGTCAAGAAGATAAAATACTTCTCCATAGTGACTCGAAACTCTGTG
  AAAGTCATTTGGAAAAACAAAGTTTATTTCATGTGTTTAATATCCTTGAAGAAGATCAGAAAGTTTTGCA
  CAGACCACCGTTCCAAGTGGAGAAAGTAGCTAGAAATTTGAAAGGAATGGCAAAAAAGAGTTTAGTCCCA
  AAAGTCAATGATTTACACATAATGTTAAGAAACCAGAAAAAACAAATGGGAGTTAAATTAAAGTCAGGTG
  CTGAGGTAAGTGAACAGCATGTTACAACCAGGGCAGATCCATTAGCTTCTCTGAAAAAACCTGATTTTCC
  TGAGGGCATTCCCCATCATTCAGGTAAAAGCTATGTAAAGCGATGGTTGCAGAACATAAACTCATATCCA
  GATTTTGAGCATAGAAAGTCCGGTCCACTATGCCAAAATAGAAGTGATGTGGTAAATTATAACCGCAATG
  GCTTTCTAGGAAATAATCTCCATACAACTTCTTCAAAAGGAAATGGTTTTTTAATGGAAAGTAATAAGAG
  CAAAACTAAAAACGACAATTGGTCAGGCAATACAAATCAAGAGACAGGTAAATCTCTTGTTGCTAAAGAT
  AATGGTGAAGAGCTCAATAAACATCACTGTGAGAGCCAGAATGGGTCTCTGTATGATTCTTACTTGGTTT
  CTTTGCATGACAATTGTACTTTGTCACAGACCACTATTAATGAGCCTAGTACTAAAAGTCATTTATCTAT
  TGAAAAGTCAAGACCAGAAGTAAAGCTTGTTTACCAAGAAATGAACTTTGCTACAAAAAGGCAAAGTATT
  GAAGTTGCCATTCAGGTAGATACTATGGGAGAAAATGTTCTAAAAGACTACTTACCAGCCTTGTTGCTAC
  GGCACCTGGAAGCTTTTGTTCCTAATAATCAGAAACATCAGAATGGAATTTCTCAAATACCAGGTTCATT
  AGCAGAGGTTGTCTTCCCTTCTGTAATAGATAATTCATCCACAAATCTCCTTCTGGCTTGGCTTTTGGTA
  CTAAACCTAAAGAGAACTATGAATAGCTTCTGTCAAAGTGATGCTCATAAGATGACCAACAGACCTTCGG
  AAACTGCTGCATTGTTGGAAGTTCTGAAGCATGTTGCCATCACAGAGGAAGCTGATGACTTGAAGGCTGC
  TGTTGCCAACTTGATGGAATCAACCAAAACTTGCAGTGGGTCCAGTGGGAGAGAACAAGATATGCTACCA
  GTAAATTGTACAGCATCCAGCCTTCATAGTGTGGACGAGTGTAATGAAAATGGGAGTGCTCAGAAGACCC
  TCTTGGATGAAGGCTATTCTGTCATGGGGGATTGTACCTCAGAAATGGTTAGCAAGTCATGTAACTCCTC
  ATGTGAGATGCACATGGTGAGCAAAACTAATCCTCCAAAACAGGTAGATGACCAGAGTGATGGCCTTCTT
  ACTAGCAATAGCTGCACTGTGAGTCAGCGCTCCACAGGGGCCTGTTTCCTTACAGATGGGGTGTATTCCC
  ATGAGGCTTGTGCTCAGAAGGAGGGCGTCTATGAGGGAGCTTGCCTAAGTGATGAGACTCACATTCCTAT
  CAGAGACTGCCATACAATTCACTCTGTGCATTCAAAAGAAAACAAATGCACTGATGATCTGGAATCAACT
  GAAGAACTCAAAACTGTTGACAAAGTTCCAAAAGGTCTAAGCATTCTGGCAGATTCTATGTATAAAAATG
  ACTCTAATGTATCTACATTTCAAAATGTCAATAAGTTAAGTTCCCAACGCACTCTCCTAAGTAAAACTTA
  TCTAGACTCTGATAAGGACTATAGTCCTCTAGAAGAATTTCAAAATTGCCCACGTAAGAAAATTGTGAAT
  AAAAAGAAATCTATTTCTTCTGATAAGGAAGAATCAAGGACTTCTGAGGAACCAAGGTCAATAACCAATA
  GCATGACATCAAGTGAAAGAAATGCCATTTCAGAATTAGAATCTTTTGAAGAATTAGAAAGCCAAGACAC
  AAGTATCTTCAATATGAATGTAAGGGCTGAAAAAAAATCTACCAAGGAAACGATGCAAAAACAATCAGAG
  GCTAGGATGAGTTCAGAATTGATAAACGTATCAGGGAGGAAAATTATAGAACAGGAAAGAAGAAATACTG
  CCATTCTGGAGACAACCGCTAGGGGGCAGGTGACACCACCATCTTTAGCTTTTTGCTACGATTCTAACAA
  AAACACCGAAAAAGAGATCAGTGAAGGAGAAACTAAGATGAGAGTTAAGAAGATGGTAGACAGCATGGAA
  AATGAAAGTTACTCGGAGTCCTCACTTAATTTTAAAAAACATCACAGAAGTCCAGGAACCTTAGACTGGT
  CAGACTATGGATCAGATAGTGAGAGTGGATATCCTTGTAAAGCATCGAGCAATAGTCACAATGATGACTC
  TGGCCAAGAGAAAGAGCCCACAAGAGGAATTGTTAAAAGAGCAATAGAAAAGCTTTATGGCAAAGCAGAG
  ATTATCAAACCACCATTTTTCCATGGGTCTATACACAAATCTCAAGTTTGTCCTTATAATTCTGTGGAAG
  TTCAGTGTGCTAAGAAAACCAATTTTTATGAGTCTGAATGCCAGTCATTGGTCTCTTCTGAACAGGTATC
  CAGAAGTTCACTCATATTTCAGGAATTCCCTCAGGTTGATGCTAATGGCATGGGAGACAGTTTTGGGGAC
  AGCAGCATAGAAAATGTTACAAAATCAAGTGCGCATGACAGGGTCTTTACAGAAAAAGAGAATGGAAAAC
  TGATTGACAATGGCAAATGGCTCCTGAGAGAAAATCATTTGTGGCGGGTGTCATCGGACAATCCTGGCAT
  GTACGGCAATGCAGACACCACATCAGTGGATACTCTAATAGATAAGAACAGCATTGAGGTGCCATATTCA
  CATTTCGGAGAGCTGGCTCCTGGTCCAACAATGGCTGAACTGTCCTCTTCAGAAATAGAGGAAATGACTC
  AACCCCTTGAAGTGAAATGCAATTATTTTAACTTCCCTCATGGTAGTGACTCTGAGCCTTTTGGTGAAGA
  TTTTCCAGATGCACAGAATAAAACTTGTCCCAAAGAGAAAATACCCAACCATCACACAGAGGAGAAGGGT
  AATTATCCATCGGAAAGACTGTGTACATCTGTTACTCAAGCCTTTGTTTCTGCTGGTAATAAAGTCCACC
  CGGTCTGCAGTGACGCTATTAAAACTCAGCCATTACCTGGGAGTAACATCACTCACGGCGCACTTCAGGA
  AGGTGACTCTTTGGATAAACTCTATGCTCTTTGTGGTCAACATTGTCCGATACTAACTGTTATTATTCAA
  CCTGTAAATGAGGAAAGCCGAGGATTTGCTTATCGCAAAGATTCTGATATTGAAAATTCTTTGGATTTTC
  AGTTATGGATGAAAATATACCCATTTATGCCACAGTCAAAGAAACACGTGTTTAGAAGTGATGGCAGGAA
  TGTGAGTGTGGGTGAAGAATTTGCTGGTAATGTCATTGGTGATCTCTGTGATCAACTTTATTTCAAAAGC
  ATGATTGACTTAGTGGATCAAAGAGCTAACTCTTTAGGGAAGGAAATTAATTTGAAGAAATTCCAACTAT
  ATTTAAAGAAAAGCTTTTCCGATCCTTTGTCCACGTCATTGCTAGTGGTGGAGAATAGGAATTCTGTTTC
  ACTAAGCCCTAGCAGTTGGACAGATAACTTCAAAAGTATTGATGAGAATAACAACTTCCTTAACAGATTA
  CCGAACTCAAGTAAAAATCCCAACCAAGTAGTAAGAGAGAACACTAATTTTCAGTTCCACTTAGAACTGT
  TTGGTCAAGTTTACTTGTTAGATATTTGCCAAGTTGAGAAACCCTTAAATATCAAAACCAGAAGTAAATT
  AGAAATGTATTACATTTTAGAGGGTGAAGTTCTTTTCATCTGGGAAGAAGAAAAATGA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_011283
• Insert Size: 6288 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_011283.2, NP_035413.1
• RefSeq Size: 7508 bp
• RefSeq ORF: 6288 bp
• Locus ID: 19888
• UniProt ID: P56716
• Cytogenetics: 1 1.65 cM
• Gene Summary: This gene encodes a member of the doublecortin family. The protein encoded by this gene contains two doublecortin domains, which bind microtubules and regulate microtubule polymerization. The encoded protein is a photoreceptor microtubule-associated protein and is required for correct stacking of outer segment disc. This protein and the RP1L1 protein, another retinal-specific protein, play essential and synergistic roles in affecting photosensitivity and outer segment morphogenesis of rod photoreceptors. Because of its response to in vivo retinal oxygen levels, this protein was initially named ORP1 (oxygen-regulated protein-1). This protein was subsequently designated RP1 (retinitis pigmentosa 1) when it was found that mutations in this gene cause autosomal dominant retinitis pigmentosa. Mutations in this gene also cause autosomal recessive retinitis pigmentosa. [provided by RefSeq, Jun 2019]
  Transcript Variant: This variant (1) encodes the longer isoform (1).