Casp8ap2 (NM_011997) Mouse Untagged Clone

CAT#: MC225082

Casp8ap2 (untagged) - Mouse caspase 8 associated protein 2 (Casp8ap2), transcript variant 1, (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Casp8ap2
• Synonyms: D4Ertd659e; FLASH
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC225082 representing NM_011997
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGCAGCAGATGATGACAATGGTGATGGAACGGGTTTGTTTGATGTCTGTCCTGCCTCTCCACTTAAAA
  ATAATGATGAAGGCTCATTGGACATATATGCTGGGTTGGACAGTGCTGTTTCTGACAGTACTGCTAGATC
  CTGTGTGTCATTCAGAAACTGTTTAGATTTGTATGAAGAGATCCTGACTGAAGAAGGAACTGCGAAGGAG
  GCAACGTACAATGACTTGCAGATAGAATATGGGAAATGTCAGCAGCAAATGAAAGACCTGATGAAAAGGT
  TTAAGGAAATACAGACACAGAACTTGAACTTAAAAAATGAAAACCAGTCTCTTAAGAAGAATATCTCAGC
  ACTTATCAAAACTGCCAGAGTGGAGATAAACCGTAAGGATGAAGAGATAAATCATCTTCACCAAAGATTG
  TCTGAGTTTCCACATTTTCGAAATAACCATAAAACTGCAAGAACAAAAGATTCACAGTCCACATCTCCCC
  ATTTGGATGATTGTTCAAAGACTGATCACGGAGTTAAAAGTGATGTTCAGAAAGATGTACATCCTAACAC
  TGCACAGCCAAACTTGGAAAAGGAAGGAAAATCGCATTCTGAAGCACAGAATCCTTTGCACTTGTCTACG
  GGTGTTGAGAAACATTGTGCCAATAATGTCTGGTCACGTTCTCCTTACCAGGTTGGAGAAGGTAACTCAA
  ATGAGGATAATAGGAGAGGAAGGAGTGGCACTAGACATAGCCAGTGTAGCAGAGGAACTGATAGAACACA
  GAAAGACTTACATAGCAGCTGTAATGACAGTGAGCCAAGGGACAAGGAGGCTAACTCCAGACTACAAGGA
  CACCCTGAGAAACATGGCAACAGTGAAGCAAGGACGGAGAGCAAAATTTCAGAGAGTAAAAGCAGCACTG
  GTATGGGATATAAAAGTGAGCGCAGTGCCTCTTCTTGGGAAAAAGAGACTTCCAGAGAAAGGCCACACAC
  TCGAGTGGAATCTCAACATGACAAAAATCTAGAGAAACAAAATGAAAGATTACAAAATATGCACAGAAAA
  GAGCTTCCGTCTCAGGACAAAACAGAAAGAAAAGTTGATGTGAAGTTTAAACCAGCAGGAGAGGAGCAGG
  GGCATCGGGGAAGAGTGGACCGGGCGTTACCTCCTCATCCCAAGAATGACGTGAAACATTACGGCTTCAA
  TAAGTATCATCCAGAAGAGAGAAGGGGAAGGGAAGATTGTAAAAGAGACAGAGGGATGAACAGTCATGGC
  TTTCAAGATAGAAGATGTTCATCTTTTCTTTCAAGCAACAGAAATAGCAAATACCCGCACTCCAAGGAAG
  TTAGTGTTGCACACCAGTGGGAAAATACTCCTTTCAAAGCAGAAAGACATAGAACTGAGGACAGGAGGAA
  AAGAGAACGAGAAAACAAAGAAGAAAGTAGACATGTGAAAAGTGACAAAAAATCACCTCCAGAACACTTA
  CAAAGGACTCATAAAGACACTAAGAAAAGCACTGCTGATGGAAAGAGACAGACTGAGCCCAAACATGGTA
  AAGGTGCAGTCTCTAACAGTGAGCTTTCTAAAGGGACAGACAGTAAAGAAGGTGCAACAAAGGTGGAGAG
  TGGGCCAAATGAAGCAAAAGGCAAGGACTTAAAGTTAAGCTTCATGGAAAAACTGAACTTAACTCTTTCT
  CCTGCTAAAAAGCAGCCTGCTTGTCAAGATAACCCACATCAAATAACTGGTGTTCCCGAGCCCAGTGGCA
  CGTGTGACTCACGGTCCTTGGAGACGACTGGAACGGTGGCATGCCTTCCTTCTGGCAGTGAACATAATAG
  AGAGGAAACCAAATCAGAGTTACCAGAGCCAAAGGAGGCTCTTTTGGCAACATCTCAACTCAGGATCAGC
  ATTCCAGAAAACAAAATGAAGGAAGAAAAGAGGTTGTTATTTAAATCTGTTGAGAATACTGTGCCTTGTG
  AACTGCTTGCTTGTGGCACGGAAATTTCCCTCCCAGCACCTGTAGAAATTGAACAAGCAAGATGCTTGCT
  TGGATCAGTGGAAGTGGAAGAGACCTGTGGTGGTGCAAGGACAGCCGCTTCTGTGGTGATGCATGTGTTA
  CCAGAACATGCTTCTGAAGATGCCAGCCAAGAATTGGACACCAAAAGACACGATGGTATAAATGCTTGTG
  CTATTTCTGAAGGTGTGAAAACAAAGGTGATTCTTTCACCAAAAGCAGCTGCAGCCAGTGAGAGCCATCT
  TGCACCTTTGGTTGAAGAACCTAGCATTTCACTAGTAAACTGTTCGGGAGACAATAATCCTAAACTTGAA
  CCTTCTCTTGAAGAGAGGCCTATAGTTGAGACTAAATCCTGTCCTTTGGAGTCTTGTTTACCTAAAGAGA
  CTTTTGTACCTTCACCACAGAAGACTGAGTTGATTGACCACAAAATAGAAACTGGAGAATCAAACTCAGT
  ATATCAAGATGATGATAACTCAGTTTTGAGTATTGACTTTAATAATCTGAGACCTATTCCAGACCCCATC
  AGCCCTCTGAATAGTCCAGTGAGACCGGTATGCAAAGTTGTTAGCATGGAGAGCTCATGTGCAATTCCAC
  TGTATGATAGCAGTCATAAAGATGAGTTTCCATCCAATTCAACTCTTTCTACCTTCAAGAGTCAGTCTGA
  TCTAAATAAGGAAAATGAAAAACCAGTTCCCAAATTTGACAAATGTTCAGAAGCAGATTCTTGTAAGCAT
  TTGTCTTTAGATGAATTAGAAGAAGGCGAAATTAGAAGTGATGATGAAGAATCTGTAGCACAAAAACGCT
  TGGAAAAGAGTGCAAGACCTAGAGTTTCTGCTGAAGTGCAGCCAGGGAAAAGCAGCCCAGGAAGCAGGAG
  GAGCACTGTGCATGTGCATAAGGACAACGGGAGGACTGCTGTAAAACTCCCTCGGGACAGACTCACATGG
  AGCAAAAGATCAAGTGAATCAAGACCCTCCAACACCGAAAGGAAAAGTAAAACAATGAGCATCTCCAGCT
  TGGAAAAAATACTTCCGCTTATCCTTGTACCCTCTTCCCTGTGGGAGGTTATGCATATGTTACGGTTGCT
  AGGTAAACATGTAAGAAAAAATTATATGAAATTCAAGATAAAATTTTCATTGACACAATTTCATAGAATT
  ATTGAATCTGCAATTTTGAGTTTCACATCACTAGTTAAATGCCTTGATTTGTCTAAGATCTGTAAGTCAG
  TAAGTACTTTACAAAAGAGTCTTTGTGAAGTTATAGAATCTAACCTTAAACAAGTGAAGAAGAATGGCAT
  AGTTGACCGTTTATTTGAACAGCAACAAACAGATATGAAAAAAAAATTGTGGAAGTTTGTAGATGAACAA
  CTTGATTATTTGTTTGAAAAGCTTAAAAAAATCCTACTAAAGTTTTGTGATTCTGTAAACTTTGAAAATG
  AGAATAGTGAAGGAAAACTTGGAAAAAAATATAAAGAGAGAACCCAACATTCAAATTGTCAGAAGAAAAA
  AATGGACAACAAAGAAATACGGAGAGAAAAAGTGCTAAAATCAGAAAATACTGTGAATTTTAAATCTTCA
  CTGGGATGTGAAAAATCTGAAGAAAAACATCAGGACCAAAATAAAACCAATGCTAGTATAGTAAAGCATG
  ATGTAAAAAGAACTTTTAGCACTTGCAGTGATAATACAAAGAACGCTGAATGTAAAGAGCAGTTTCTGGA
  AAAGAGCTGCCCGAGTACCCCTAGGCCAGGAAAAGATGAAGGACATACTGAGGAGGAGGCACAGGCGGCA
  CAGCATGCAAGTGCTAAGTCCGAACGGAGCTTTGAGATCCTTACTGAGCAGCAGGCATCCAGCCTTACTT
  TTAACTTAGTGAGTGATGCACAGATGGGTGAGATATTTAAAAGCTTGCTACAAGGTTCTGATCTGTTGGA
  CACAAGTGGCACTGAAAAGGCAGAGTGGGAATTAAAGACTCCAGAGAAACAGCTGCTGGAAAGCCTCAAG
  TGTGAATCTGCACCAGCTTGTGCAACAGAAGAGCTGGTTTCAGAGGGGGCTTCTCTTTGTCCAAAAGTGA
  TCAGTGATGATAATTGGTCTTTATTATCATCTGAAAAGGGTCCATCTTTATCTTCAGGGCTTTCACTGCC
  AGTTCATCCTGATGTGTTAGATGAAAATTGTATGTTTGAAGTATCTTCTAACACTGCTTTAGGTAAAGAT
  AATGTATACAGCTCAGAAAAGAGTAAGCCCTGCATCTCTTCCATACTCTTAGAAGATCTTGCGGTCTCTT
  TAACAGTACCGTCACCTCTGAAATCAGATGGCCATTTGAGTTTCTTAAAGCCAGAAGTTTTGTCAACTTC
  AACTCCTGAAGAAGTTATTAGTGCACATTTTAGTGAGGATGCTTTGCTTGAGGAAGAGGATGCATCTGAA
  CAGGACATTCATCTAGCTCTGGAGTCTGATAACTCAAGCAGTAAGTCAAGCTGTTCATCATGGACAAGCC
  GGTCTGTTGCTTCAGGCTTTCAGTACCACCCTAATCTTCCCATGCATGCTGTCATAATGGAAAAGTCCAA
  TGATCATTTCATTGTGAAAATACGGCGTGCAACACCATCTACCTCCCCTGGCCTTAAACATGGTGTGGTA
  GCTGAGGAGTCATTGACATCTTTGCCTAGAACTGGAAAAGAAGCTGGTGTAGCAACAGAGAAAGAACCTA
  ACCTGTTTCAGAGTACAGTTTTAAAACCTGTCAAGGACTTGGAAAATACTGATAAAAATATTGATAAGAG
  TAAACTAACTCATGAAGAACAGAACTCTATAGTACAAACACAGGTTCCAGATATATATGAATTTCTTAAA
  GATGCCTCAAATAAGGTGGTTCATTGTGATCAAGTGGTTGATGATTGCTTCAAGTTGCATCAAGTATGGG
  AACCAAAAGTTTCTGAGAACCTTCAAGAGTTGCCTTCAATGGAGAAAATCCCACACTCTCTTGATAATCA
  TCTTCCTGATACACACATAGATCTAACGAAAGATTCAGCCACTGAGACCAAAAGCTTGGGGGAGCTAATG
  GAAGTAACAGTTTTAAATGTTGATCACTTGGAATGTTCTCAAACCAACTTAGATCAAGATGCAGAGATAA
  CATGTAGTTCTTTACAGCCTGATACTATAGATGCTTTTATTGATTTGACACATGATGCTTCAAGTGAGAG
  TAAAAATGAAGGTAGTGAACCTGTGTTAGCTGTTGAAGGTATGGGATGCCAGGTAATATGTATAGATGAG
  GATACCAACAAAGAAGGAAAGATGGGAAGGGCAAACAGTCCTTTAGAAAGTATTGTTGAAGAAACTTGTA
  TTGATTTGACCTCAGAGTCTCCTGGCTCCTGTGAAATCAAGAGACATAATTTAAAGTCGGAGCCTCCATC
  AAAGTTGGATTGTTTAGAGTTGCCTGAAACTCTGGGTAATGGTCACAAGAAGAGGAAAAACAGTCCTGGT
  GTTAGTCACTCTTCTCAGAAAAAACAAAGAAAGGACATAGACTTAAGTAGTGAAAAGACCCAGAGACTTA
  GTCCCAATTCTGATAGAAATGGTGATGCTCACAGAAAGCAAGCGAGCAAGAAAAGAGAACCTGCAGTAAA
  TGAAACGTCCTTGTCATCAGAGGCCAGCCCAGAGGTGAAGGGTTCAACAGCAGTACTTGCTGCTTCCCCA
  GCAAGCCTTTCTGCAAAAAATGTTATCAAAAAGAAGGGAGAAATTATAGTTTCATGGACAAGAAATGATG
  ACCGGGAAATTTTACTGGAATGTCAGAAAAGAATGCCGTCCCTGAAAACATTTACTTATTTAGCTGTCAA
  GCTGAATAAAAATCCAAATCAGGTTTCAGAGAGGTTCCAGCAGCTGAAAAAGCTCTTTGAGAAGTCAAAA
  TGCAGGTAG
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_011997
• Insert Size: 5889 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_011997.3, NP_036127.2
• RefSeq Size: 6813 bp
• RefSeq ORF: 5889 bp
• Locus ID: 26885
• UniProt ID: Q9WUF3
• Cytogenetics: 4 14.27 cM
• Gene Summary: Participates in TNF-alpha-induced blockade of glucocorticoid receptor (GR) transactivation at the nuclear receptor coactivator level, upstream and independently of NF-kappa-B. Suppresses both NCOA2- and NCOA3-induced enhancement of GR transactivation (By similarity). Required for histone gene transcription and progression through S phase (By similarity). Required for histone gene transcription and S phase progression (By similarity). Involved in TNF-alpha-induced activation of NF-kappa-B via a TRAF2-dependent pathway. Acts as a downstream mediator for CASP8-induced activation of NF-kappa-B. Required for the activation of CASP8 in FAS-mediated apoptosis.[UniProtKB/Swiss-Prot Function]
  Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.