Kif20b (NM_183046) Mouse Untagged Clone

CAT#: MC224920

Kif20b (untagged) - Mouse kinesin family member 20B (Kif20b), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Kif20b
• Synonyms: 33cex; B130024C23; C330014J10Rik; magoo; Mphosph1
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC224920 representing NM_183046
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGAATCTCACTTGAATCCAGATGGAGTGCCTAGACCGTCTTACGTTTTTAGTGCTGACCCAATTGCAA
  GGCCTTTGGAAATCAATTTTGATGGTGTTAAGCTTGATCTCTCTCATGAGTTTTCCTTAGTCGCCTCAAA
  CCCTGCGGCAAACAGTTTGGGATCTAAAAACTATCTTCAAGTTTGTCTTCGAATAAGACCATTTACACAG
  TCAGAAAAAGAACATGAGGCTGAGGGCTGTGTGCAAGTTTTGGATTCACAGTCTGTTCTGCTGAAAGACC
  CTCAAAGCATCCTTGGCCACTTAAGTGAGAAGAGCTCTGGACAGGTGGCACAGAAATTCAGTTTTTCTAA
  GGTTTTTGGACCTGAAACTTCACAGAAAGAGTTCTTTCTGGGTTGCATTATGCAGCCAGTAAAGGACCTC
  TTAGAAGGACACAGTCGACTGATCTTCACATATGGTCTGACCAATTCTGGAAAAACATATACATTTCAAG
  GCACAGAAGAAAATATTGGTATTTTGCCTAGAACACTGAATGTATTGTTTGATAGTCTTCAGGAAAGACT
  ATATACGAAGATGAGCTTCAAACCACACAGATGTAGAGAATACTTAAAATTATCATCTGATCAAGAGAAG
  GAGGAAAGTGCTAACAAAAATACATTGCTGCGACAAATTAAGGAGGTTACCATACATAATGACAGTTATG
  ACGTTCTTTGTGGACACTTAACAAACTCTTTGACTATCCCAGAATTTGAAGAATCCGTGAACAGTTGTGA
  CCAGTCCAGTCTGAATGTGGATAATATAAAGTATTCTGTGTGGGTTTCTTTCTTTGAAATTTACAATGAA
  AGTATTTACGATTTGTTTGTTCCTGTGTCCTCTAAGTTTCAAAAGAGAAAAATGTTACGACTTTCCCAAG
  ATATAAAGGGCTATTCTTTTATAAAAGATCTGCAGTGGGTCCAGGTATCTGACTCTAAAGAAGCATATAG
  ACTCTTAAAACTAGGAGTGAAGCATCAGAGCGTTGCTTTCACCAAACTGAACAATGCTTCTAGTAGAAGT
  CACAGCATATTCACTATTAGAATATTACAGATAGAAGATTCTGAAATACCTCGTGTAACACGAGTTAGTG
  AATTGTCTCTATGTGATCTTGCTGGTTCAGAACGAAGCATGAAGACACAAAACGAAGGTGAAAGGTTAAG
  AGAGGCTGGGAATATCAACACTTCTTTATTGACTCTGGGAAAGTGTATCAATGTTTTGAAGAACAGTGAA
  AAGTCAAAGGTTCAGCATGTGCCTTTCCGAGAAAGTAAACTGACCCACTATTTCCAAAGTTTTTTCACTG
  GAAAAGGGAAAATATGCATGATCATCAATATTAGTCAGTCTTGCTCTGCCTATGATGAGACACTCAATGT
  CCTGAAGTTCTCAACCACTGCGCAAAGGGTCTATGTTCCGGATACTTTAAGTTCTTCTCAAGAGAAATCT
  TTTGCATCTAACAAATCTTTACAAGATGTATCATTAGACAGTAATTTGGACAATAAAATACTAAATGTAA
  AAAGAAAAACTGTTTCATGGGAAAATAGTCTAGAAGATGTGCTTGAAAATGAAGATTTGGTTGAGGACTT
  AGAAGAAAATGAAGAAACACAAAACATGGAAACGGAACTTACAGATGAAGATAGTGATAAGTCATTAGAG
  GAATGCAGAGTTTCCACCTGCCACAAAAAGAACAAGGAACTGTTGGATTTAATAGAAAAGTTGAATAAAA
  GACTAATAAATGAAAATAAAGAAAAATTAACATTGGAACTTAAAATCCGAGAAGAAGTTACACAGGAATT
  CACTCAGTATTGGAGCCAACGGGAAGCCGATTTTAAGGAGACACTTCTTCATGAACGAGAGATATTAGAA
  GAAAACGCTGAACGTCGCTTGGCAATCTTCAAAGATTTGGTTGGAAAATGTGACAGTCAAGATGAACCAA
  CAAATAGAATTTGTGACATAGAACTTGAAACTGAAGAAGCTCATAATTATGTAGGAGTTGAAGATATTTT
  TCATTCTCTTCAAGATGATGTCACTGATATTAAGAAACAGGCCGAACTTGCTCATTTGTATATTACATCT
  CTTGTTGATCCCCAGGAAGCTATTGCCTGTTTGCAGCTAAAGTTTAATCAAGTTAAAGCAGAATTAGCTG
  AAACTAAAGAAGAATTAATTAAAGCCCAAGAAGAGCTAAAAAACAGAGAGAGCAACTCTTTGGTTCAGGC
  ACTCAAGACATCAAGTAAGGTTGATACATCTTTAACCAGCAATAAGTCAACTTGTAATGAAACAAGTGAA
  ATGCCAAAGAACAGTAGAGCCCAGACACATTCAGAAAGGAAAAGATTAAATGAAGATGGACTTCAGCTTG
  GTGAGCCACCAGCAAAGAAAGGGCTTATACTCGTTAGTCCACCCATCACCGAAGAGCAAAACAAAATGGG
  AGAAATGCAACAGTCTGTTTCAGAAGTTGTGGAAGGCAATAGAGTTTTGAAGGAAAAGAATGAAGAGCTA
  AAAAGACTTTTAACTATTGGTGAGAATGAACTCAGAAATGAAAAGGAGGAAAAAGCAGAATTAAATAAAC
  AGGTTGTGAGTTTGCAGCAGCAACTTCGTTTCTTTGAAGAAAAGAACTCATCCCTGAGGGCAGATGTAGA
  GCAAATCCAGGCCAGTTACAACAGTGCAGTTGCCGAGCTGCAAACACAGAAAGCCGTGAACCAGGAGCAG
  AGGGACAGGATCCTGAAATTATCACAGGAGATGGAGACTGCTGCAAGAAGTATCGAGAGCAATGTTTCAC
  AGATAAAACAAATGCAAACAAAAATAGATGAATTGCGGTCACTTGATTCACCTTCTCATATTTCAAAAAT
  AGATTTACTTAATCTCCAGGATCTATCAAGTGGTGCTAAAGGGGATAATTGTCTGAACACATCACAGCAG
  CTTCCAGGTGGTGACTTCTCAAGTACGTGGGTTAAAGAATATCACACTCAGGAGATCAGCAGGGAAAATT
  CCTTCCACGCGAGTATTGAAGCCATCTGGGAAGAATGTAAAGAGATTGTGAAGGCTTCCTCCAAAAAGTC
  TCATCAGATTCAGGGACTAGAAGAACAAATTGAAAAATTACAGGTGGAAGTAAAAGGATACAGGGAGGAG
  AACAGTGACCTCCGAGCACAGGAGAGCCAGGGTAAGAATAGAGATCACCAGCTGAAGGAGAAAGAAAGTC
  TCATCCAGCAGCTCAGAGAAGAACTGCAAGAAAAAAGTGTCAGTCTCCGTGTTCAAGTACAGCTTGTAGC
  GGAAAGAGAGCAAGCTCTTTCAGAGCTTTCCCAGGATGTTACCTGCTACAAGGCAAAAATAAAGGACCTT
  GAGGTGATAGTAGAGACCCAGAAAGATGAGTGTAAGCGCTTAGTTGAGTTAGAGCAAAGCATTTTAGAGA
  AGGAATCTGCCATCTTAAAACTGGAAGCAAATCTAAAGGAATGTGAAGCAAAGCATCAGGATCACATCAG
  AACCAACGATCTAAGTGCAAAGGAAGTCAAGTTCAGAGAAGAAGTCACACGGTTGGCGAATAATTTGCAT
  GATACGAAACAGTTACTTCAGTCAAAGGAAGAAGAAAATGAAATTAGCAGACAAGAGACAGAAAAGTTGA
  AAGAGGAGCTTGCTGCAAACTCTATTCTTACTCAGAATCTCAAAGCAGACCTTCAGAAGAAGGAAGAAGA
  TTGTGCTGAGCTGAAAGAGAAGTTCATTGATGCCAAAAAGCAGATTGAGCAGGTACAGAGGGAGGTATCT
  GTAATGCGTGATGAAGAGAAATTATTGAGGATTAAAATTAATGAACTGGAGAAAAAGAAAAACCAGTATT
  CTCAGGACTTAGATATGAAACAACGAACCATTCAGCAACTTAAGGAGCAGTTAAGTAATCAGAAAATGGA
  AGAAGCTGTACAACAGTATGAGAAAGTGTGCAAAGATCTCAGTGTTAAGGAGAAGCTGGTTGAAGACATG
  CGACTGACGCTAGTGGAGCAGGAGCAGACTCAGGCAGAGCAGGACCGGGTGCTCGAGGCCAAGTCAGAGG
  AAGCAGACTGGCTAGCCACAGAATTGGATAAATGGAAAGAAAAATTCAAAGATCTGGAAACCAGAAGTAA
  TCAGAGGTTAAACACAGGAACCATGGATGACCTAGACGTGCTTACCAGGAAGTTCAGCAAGCTTCAGGAC
  GAGCTGCAGGAATCTGAAGAGAAATATAAAGCTGATAGAAAGAAGTGGTTAGAAGAAAAAGCTGTCCTTA
  CCACTCAAGCGAAAGAAGCAGAAAATGTACGAAACAGGGAGATGAGAAAATATGCTGACGACAGGGAGCG
  CTGTTTAAAGCTGCAGAATGAAGTGGAAACACTGACAGCACAGCTGGCAGAGAAAAATAGTGAGCTTCAG
  AAGTGGAGAGAAGAGCGTGACCAGCTGGTCACAGCTGTAGAGACACAGATGAAGGCTCTGCTCTCCAGCT
  GCAAGCACAAGGATGAAGAAATCCAGGAACTAAGAAAGGCTGCAGCAAAGAGCACCGGGACAGAAAACCA
  AACCATGAATCCCAAGCCTGAATATAATGATTCCGTTGATCTTGGTGGAGTTGAAACTGAACCTCAGTCA
  ACAAGTTTGGAAATTTCTAGGAACACAGCAGAGGACGGATCTGTAGTTCTTGACTCTTGTGAAGTGTCAA
  CAGAAAATGTACAAAGTACTCGATTTCCAAAACCTGAATTGGAGATTCAGTTTACACCTTTGCAGCCAAA
  CAAAATGGCAGTGAAGCACCCTGGTTGTCCCACACCAGTCACAATTAAGATCCCCAAGGCACGGAAGAGG
  AAGAGTGGTGAAGTGGAGGAGGACTTGGTGAAATGTGAAAATAAGAAGAATTCAACCCCCAGAAGTAATG
  TGAAGTTTCCCGTTTCAGAGCATAGAAATTCCCCTGTCAAAAAGGAACAAAAGGTTTCCGTTGGTCCATC
  ATCTAAGAAAACTTACTCCTTACGGAGCCAAGCATCTACAGTTAGTGCAAACATAGCCTCTAAAAAAAGA
  GAGGGAACACTACAGAAATTTGGAGACTTCTTGCAGCATTCTCCAACAATTCTTCAATCAAAAGCAAAAA
  AGATAATTGAAACAATGAGTTCTCCAAAGTTATCAACGGTAGAAGTAAGTAAAGAAAATGTGTCCCAGCC
  AAAAAAAGCCAAACGGAAATTATACAGAAATGAAATTTCATCTCCCATCAACATATCTGGCCAAGTGATT
  TTAATGGAACAGAAAGTAAAAGAAACTGATCATCAGATTCTCAAACGACGGCTTCGAACACGCACAGCCA
  AATAA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_183046
• Insert Size: 5325 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_183046.1, NP_898867.1
• RefSeq Size: 5563 bp
• RefSeq ORF: 5325 bp
• Locus ID: 240641
• UniProt ID: Q80WE4
• Cytogenetics: 19 C1
• Gene Summary: Plus-end-directed motor enzyme that is required for completion of cytokinesis (By similarity). Required for proper midbody organization and abscission in polarized cortical stem cells (PubMed:24173802). Plays a role in the regulation of neuronal polarization by mediating the transport of specific cargos. Participates in the mobilization of SHTN1 and in the accumulation of PIP3 in the growth cone of primary hippocampal neurons in a tubulin and actin-dependent manner (PubMed:23864681). In the developing telencephalon, cooperates with SHTN1 to promote both the transition from the multipolar to the bipolar stage and the radial migration of cortical neurons from the ventricular zone toward the superficial layer of the neocortex (PubMed:23864681). Involved in cerebral cortex growth (PubMed:24173802). Acts as an oncogene for promoting bladder cancer cells proliferation, apoptosis inhibition and carcinogenic progression (By similarity).[UniProtKB/Swiss-Prot Function]