Bcor (NM_175045) Mouse Untagged Clone

CAT#: MC224874

Bcor (untagged) - Mouse BCL6 interacting corepressor (Bcor), transcript variant c, (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Bcor
• Synonyms: 2900008C10Rik; 5830466J11Rik; 8430401K06Rik; BcorR; D930024N20Rik; mKIAA1575
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC224874 representing NM_175045
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGCTTTCTGCAACCCCTCTGTATGGGAACGTTCACAGCTGGATGAACAGCGAGAGGGTCCGCATGTGTG
  GAACAAGTGAAGACAGGAAAATTCCTGTGAATGATGGCGACGCTTCAAAAGCCAGGCTGGAGCTGAGGGA
  GGAGACTCCCCTGAGTCACAGCGTGGTGGATACCAGTGGAGCCCATCGGATCGATGGCCTGGCAGCACTG
  AGCATGGACCGCACAGGCCTCATCCGGGAAGGGCTCCGGGTCCCTGGAAACATCGTTTATTCTGGCTTGT
  GTGGATTGGGCTCAGAAAAAGGTCGGGAGGCTACCCCAAGCTCTCTCAGTGGCCTTGGGTTTTCTTCGGA
  AAGAAATCCAGAGATGCAATTCAAACCGAATACTCCCGAGACAGTGGAGGCTTCTGCTGTCTCTGGAAAA
  CCCCCAAATGGCTTCAGTGCTATATACAAAACACCGCCTGGGATACAAAAGAGCGCTGTAGCTACAGCGG
  AAAGCTTGGGTTTGGATAGGCCTGCCAGTGACAAACAGAGCCCTCTCAACATCAATGGTGCTAGTTACCT
  GCGGCTGCCCTGGGTCAACCCTTACATGGAGGGGGCCACTCCAGCCATATACCCTTTCCTCGACTCGCCA
  AATAAGTATTCACTGAATATGTACAAGGCCTTGCTACCTCAGCAGTCCTACGGCTTGGCCCAGCCACTGT
  ATTCTCCTGTCTGCACCAGTGGGGAACGCTTCCTCTACCTGCCACCCCCACACTATGTCAACCCTCACAT
  CCCCTCCTCCTTGGCTTCACCCATGAGGCTCTCCACACCTTCAGCCTCTGCGGCCATTCCACCTCTCGTC
  CACTGCTCAGACAAAAGCCTCCCATGGAAGATGGGCGTCAACCCTGGGAACCCAGTAGATTCCCACAGTT
  ACCCCCACATCCAAAACAGTAAACAGCCCCGGGTGACCTCTGCCAAGGCAGTCAATAGTGGCCTGCCAGG
  GGACACAGCTCTCCTGTTGCCTCCTTCACCTCGGCCCTCAGCCCGGGTCCACCTTCCAACTCAGCCCGCT
  GCAGAGACCTACTCCGAGTTCCACAAGCACTATCCCAGGATCTCCACCTCTCCCTCAGTCACCCTGACGA
  AGCCATACATGACAGCCAATAGCGAGTTCTCTACATCCAGGCTGTCCAATGGCAAGTACCCCAAGGCTCT
  AGATGGGGGCGACTGTGCTCAATCCATGCCTGGGCACACCCGGAAGACAACGGTTCAAGACAGAAAAGAT
  GGGGGCTCACCACCTCTGTTGGAAAAGCAGACCGTTACCAAAGATGTCACAGACAAACCACTTGACCTGT
  CTTCTAAAGTGGTGGATGCGGACGCTTCCAAAGGTGACCACATGAAAAAGATGGCTCCCACAGTCCTGGT
  TCACAGTCGGGCTGCAAGTGGCTTAGTGCTCTCTGGAAGTGAGATTCCGAAAGAAACACTATCTCCTCCA
  GGAAATGGATGTTCTATCTATAGATCAGAGATCATCAGCACTGCTCCCTCATCCTGGGTGGTGCCAGGGC
  CAAGTCCTAATGAAGAGAACAATGGCAAAAGTCTGTCACTGAAAAACAAGGCTTTGGACTGGGCAATACC
  GCAACAGCGGAGTTCCTCGTGTCCCCGCATGGGTGGCACAGATGCCGTGGTCACTAATGTTTCAGGGTCC
  GTGTCCAGCTCAGGACGCCCAGCCTCTGCATCACCAGCCCCCAACGCCAACGCCAATGCAGATGGCACCA
  AGACCAGCAGGAGCTCGGTGGATACCACGCCATCAGTCATCCAGCATGTGGGCCAGCCCTCATCCACGCC
  TGCCAAGCACGGTGGCAGCACCAGCAGCAAGGGAGCCAAAGCCAACCCAGAACCGAGCTTCAAAGCGAGT
  GAGAATGGCCTCCCGCCAACCTCAATATTTCTATCTCCAAATGAAGCATTCAGGTCCCCAGCAATTCCCT
  ACCCTAGGAGTTACCTCCCTTACGCAGCACCAGAAGGCATCGCTCTAAGTCCCCTCTCTTTACATGGCAA
  AGGACCTGTGTATCCTCACCCAGTTTTGTTACCCAATGGCAGTCTGTTTCCTGGGCACCTTGCCCCAAAG
  CCTGGCCTGCCTTACGGGCTGCATACGAGCAGGCCAGAATTTGTGACCTACCAAGATGCCCTGGGCCTGG
  GCATGGTCCATCCCATGTTGATCCCACACACGCCCATTGAGATCACAAAAGAGGAGAAGCCGGAGAGACG
  CTCCCGCTCCCATGAGAGAGCCCGTTATGAGGACCCAACCCTCCGTAGCCGGTTTTCTGAGATGTTGGAA
  GCTAGCAGCACCAAACTGCATCCAGAAGTCCCCACTGACAAGAACCTGAAGCCAAACTCTAGCTGGAATC
  AAGGGAAGACTGGGGTCAAAAGCGACAAACTGGTCTACGTAGACCTTCTCCGAGAAGAAGCAGACACTAA
  AACTGATGCAGGGGCACCCAAAGCAGGCCTTGTAGCCGAGAATGTAGGTCAGGACACCGAGGCCACCAAG
  CCCTCAGCTGACCCTGTGATCCAACAACGCCGTGAATTCATCTCCCTCAGAGAGGAGCTGGGCCGAATCA
  CTGACTTCCATGAATCTTTCACTTTCAAACAGGCCTCAAGCCAGCCAGTGTTCAGCTTAGGCAAGGATAG
  TGGTGCAGCAGGAACCAACAAAGAGAACCTGGGTGTGCAGGTAGCAACTCCATTCTTGGAGACAGCTCTG
  GGCAGTGAGGGCCCTGCTGTGACTTTTGGTAAAACCCAAGAGGATCCCAAACCATTTTGTGTGGGCGGTG
  CCCCTCCAAACATGGATGTCACCCCCGCCTATACCAAAGAAGGAACTGATGAGGCCGAATCCAACGATGG
  CAAAGTTCTGAAACCCAAGCCATCCAAGCTGGCAAAGAGAATTGCTAACTCGGCAGGTTATGTGGGCGAC
  CGATTCAAGTGTGTCACCACCGAACTGTATGCAGATTCCAGTCAGCTCAGCCGAGAGCAGCGGGCATTGC
  AGATGGAAGGATTACAAGAGGACAGTATTTTATGTCTACCCGCTGCTTACTGTGAGCGTGCAATGATGCG
  CTTCTCAGAGTTGGAGATGAAAGAGAGAGAAGGTAGCCACCCAGCAACCAAAGACTCCGAGGTGTGCAAA
  TTCAGCCCAGCCGACTGGGAAAGGTTGAAAGGAAATCAGGAAAAGAAGCCAAAGTCAGTCACCCTGGAAG
  AGGCCATTGCCGACCAGAATGACAGTGAGAGATGTGAGTATAGCACTGGAAACAAACATGATCTCTTTGA
  AGCCCCAGAGGACAAAGATCTTCCTGTGGAAAAGTATTTCTTGGAGAGGCCACCTGTGAGTGAGCCACCC
  AGTGACCAGGGGGTGGTGGACACGCCACACAGCCCCACCCTCCGGCTAGACAGGAAACGCAAACTGTCAG
  GTGACAGCACCCACACTGAGACCGCTGTGGAAGAGCTAGCTGAGGACCCTCTGAAAGCCAAGCGAAGACG
  GATCTCCAAAGGGCTCCATCCTAAAAAGCAACGCCACTTGCTGCACCTTAGAGAACGGTGGGAGCAGCAG
  GTGTCGGCAGCCGAGAGCAAACCTGGCCGGCAAAGCAGGAAGGAAGTGGCCCAGGCTGTTCAGCCTGAGG
  TCACCTCCCAGGGGACTAACATCACTGAAGAGAAGCCTGGCAGGAAAAAGGCAGAGGCCAAAGGCAACAG
  AGGCTGGTCTGAAGAGTCGCTCAAATCCTGTGACAATGAGCAAGGCTTGCCTGTGCTCTCAGGCTCTCCG
  CCCATGAAGAGCCTTTCATCCACCAATGCAAGTGGCAAAAAGCAGACTCAGCCAAGCTGCACGCCAGCCT
  CAAGGCTGCCTGCCAAACAGCAGAAAATTAAAGAAAGCCAGAAGACAGATGTGCTGTGCACAGGGGAAGA
  CGAGGATTGCCAGGCTGCCTCCCCGCTGCAAAAATACACAGACAACATCGAGAAGCCATCCGGGAAGAGA
  CTGTGCAAAACCAAGCACTTGATACCTCAGGAGTCCAGGAGGAGCTTGCAGATCACAGGCGACTACTATG
  TGGAGAACACTGACACTAAGATGACTGTGCGGAGATTCAGAAAACGACCTGAGCCCAGTTCGGACTACGA
  TTTGTCACCACCAGCCAAGCAGGAGCCAAAGCCCTTTGACCGTCTACAACAATTGCTACCGGCCACCCAG
  GCCACCCAGCTGCCACGCTCAAATTCTCCTCAAGAGACCACCCAGTCTCGCCCCATGCCGCCAGAAGCTC
  GGAGACTTATTGTCAATAAGAATGCTGGCGAGACCCTCCTGCAGCGGGCTGCCCGGCTAGGCTATGAGGA
  AGTGGTCTTATATTGCCTGGAGAACAAGGTCTGTGATGTCAATCATCGAGACAATGCTGGCTACTGTGCT
  CTGCATGAAGCTTGCGCCAGGGGATGGCTCAACATCGTGCGCCACCTCCTTGAATATGGCGCTGATGTCA
  ACTGCAGTGCCCAGGATGGAACCAGGCCTCTGCATGATGCTGTGGAGAATGACCACTTAGAAATTGTACG
  ATTGCTTCTTTCCTATGGTGCTGACCCTACTTTGGCCACATACTCAGGGAGAACCATCATGAAAATGACC
  CACAGTGAACTTATGGAGAAGTTTTTAACAGACTATTTAAATGACCTGCAGGGTCGCAGTGAAGATGACA
  CCAGCGGCGCTTGGGAGTTCTATGGCAGCTCTGTGTGTGAACCAGATGACGAAAGTGGGTACGATGTTTT
  GGCTAATCCCCCAGGACCAGAAGACCCAGATGAGGAAGAGGATACCTATAGCGATTTGTTTGAGTTTGAG
  TTTGCTGAAAGCTCCCTCTTGCCGTGTTATAACATCCAAGTGTCTGTCGCTCAGGGGCCACGAAACTGGC
  TTCTGCTCTCAGACGTGCTCAAGAAGTTGAAAATGTCCTCCCGGATATTCCGTAGCAATTTTCCCAATCT
  GGAAATTGTCACCATTGCAGAGGCGGAGTTTTACCGACAGGTCTCAACAAGTCTCTTGTTCTCCTGCCCC
  AAAGACCTGGAAGCCTTCAATCCTGAAAGCAAGGAGCTGTTGGATCTGGTGGAATTCACCAATGAGCTCC
  AGACACTGCTGGGCTCCTCTGTGGAGTGGCTCCACCCTAGTGACACGGGCCATGAAAACTACTGGTGA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_175045
• Insert Size: 5178 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_175045.3, NP_778210.2
• RefSeq Size: 6857 bp
• RefSeq ORF: 5178 bp
• Locus ID: 71458
• UniProt ID: Q8CGN4
• Cytogenetics: X A1.1
• Gene Summary: Transcriptional corepressor. May specifically inhibit gene expression when recruited to promoter regions by sequence-specific DNA-binding proteins such as BCL6 and MLLT3. This repression may be mediated at least in part by histone deacetylase activities which can associate with this corepressor. Involved in the repression of TFAP2A; impairs binding of BCL6 and KDM2B to TFAP2A promoter regions. Via repression of TFAP2A acts as a negative regulator of osteo-dentiogenic capacity in adult stem cells; the function implies inhibition of methylation on histone H3 'Lys-4' (H3K4me3) and 'Lys-36' (H3K36me2) (By similarity).[UniProtKB/Swiss-Prot Function]
  Transcript Variant: This variant (c) lacks a segment in the CDS, as compared to variant a. The resulting isoform (c) lacks an internal segment, as compared to isoform a.