Setd1a (NM_178029) Mouse Untagged Clone

CAT#: MC224870

Setd1a (untagged) - Mouse SET domain containing 1A (Setd1a), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Setd1a
• Synonyms: BC010250; KMT2F; mKIAA0339; mNSC1; Nsccn1
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC224870 representing NM_178029
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGACCAGGAAGGTGGGGGAGACGGGCAGAAAGCCCCGAGCTTCCAGTGGCGGAACTACAAGCTCATAG
  TGGATCCTGCTTTGGACCCTGCTTTGCGCAGGCCTTCCCAGAAGGTGTACCGCTATGACGGAGTCCACTT
  CAGTGTCAGTGACTCAAAGTATACCCCCGTGGAAGACCTCCAGGACCCCCGCTGTCATGTCAGGTCCAAA
  GCCAGAGACTTTTCCCTCCCGGTTCCTAAGTTTAAGCTGGATGAGTTCTATATTGGACAGATACCACTGA
  AGGAAGTAACTTTTGCGAGGCTCAATGACAATGTGAGGGAAACCTTCCTGAAGGATATGTGCCGGAAATA
  TGGAGAGGTGGAAGAAGTGGAGATCCTTCTTCATCCCCGCACTCGAAAGCACCTAGGCCTGGCCCGTGTG
  CTCTTCACCAGCACTCGGGGCGCCAAGGAAACTGTCAAAAACCTCCACCTCACCTCTGTCATGGGCAACA
  TCATTCATGCCCAGCTTGATATCAAAGGCCAACAACGAATGAAGTACTATGAATTGATTGTCAATGGCTC
  TTACACTCCTCAGACTGTGCCCACTGGGGGCAAGGCCTTGAGTGAGAAGTTCCAGGGTTCTGGTGCAGCC
  GCTGAGACGACTGAAGCCCGCCGACGGTCTTCCTCGGACACAGCTGCCTATCCAGCAGGCACTACTGTGG
  GGGGCACCCCTGGCAATGGCACTCCCTGCTCCCAAGATACAAATTTCTCCAGCAGCCGACAAGATACTCC
  ATCTTCCTTTGGCCAGTTCACCCCTCAGTCCTCCCAAGGAACCCCCTACACATCTCGGGGTAGCACCCCC
  TACTCTCAGGACTCTGCCTACTCCAGCAGCACCACTTCAACCTCCTTCAAACCCCGGCGGTCAGAGAACA
  GCTATCAAGATTCTTTTTCTCGCCGCCATTTCTCTACATCTTCAGCCCCTGCAACCACCGCTACTGCCAC
  CTCAGCAACTGCTGCAGCTACTGCAGCCTCCTCCTCATCTTCCTCCTCCTCGTCATCGTCCTCCTCCTCG
  TCGTCTTCTTCCTCAGCCTCTCAGTTTCGTGGTTCTGACTCTAGCTACCCAGCATATTATGAAAGCTGGA
  ATCGTTACCAGCGCCATACTTCCTATCCACCTCGCCGGGCAACTAGAGAGGACCCTTCTGGGGCTTCATT
  TGCCGAAAATACGGCTGAGCGCTTCCCACCTTCCTATACCTCCTATTTGGCCCCTGAGCCTAACCGATCC
  ACTGACCAAGACTACCGGCCTCCTGCCTCAGAGGCCCCACCTCCAGAACCTCCAGAACCTGGTGGTGGTG
  GTGGTGGTAGTGGTGGTGGTGGTGGTGGTGGTGGTGGTGGTGGTGGTGGGGCACCCAGCCCTGAGAGAGA
  AGAAGCCCGGACTCCCCCACGCCCAGCTTCCCCTGCACGCTCTGGCTCCCCAGCCCCAGAGACCACCAAC
  GAGAGTGTGCCCTTTGCTCAGCACAGCAGTTTGGATTCCCGTATTGAAATGCTGCTGAAGGAACAACGCT
  CCAAGTTTTCTTTCTTGGCTTCTGATACAGAGGAAGAGGAAGAGAACAGCAGTGCAGGCCCTGGGGCTAG
  AGATGCAGGGGCTGAGGTGCCTTCTGGGGCAGGTCATGGGCCCTGTACACCTCCTCCTGCACCAGCTAAT
  TTTGAAGATGTAGCACCTACAGGGAGTGGAGAGCCAGGGGCTGCCCGGGAGTCACCAAAGGCCAATGGAC
  AGAACCAGGCTTCTCCATGTTCTTCCGGAGAAGATATGGAGATCTCTGATGATGACAGGGGTGGCTCACC
  ACCTCCAGCCCCAACACCCCCCCAGCAGCCGCCACCGCCACCACCTCCCCCTCCTCCCCCCCCTCCTCCC
  TACCTTGCTTCCCTTCCCCTTGGCTATCCTCCCCACCAACCTGCCTACCTCCTCCCACCCCGCCCAGATG
  GACCACCCCCCCCTGAGTACCCTCCGCCACCTCCTCCACCACCACCCCACATCTATGACTTTGTGAACTC
  CCTGGAACTTATGGATCGACTTGGGGCACAGTGGGGAGGGATGCCCATGTCCTTCCAGATGCAGACCCAG
  ATGTTAACACGGCTCCACCAGTTACGGCAGGGCAAGGGATTGACTGCAGCCTCAGCTGGTCCTCCTGGCG
  GGGCTTTTGGCGAGGCCTTTCTCCCTTTTCCACCTCCACAAGAGGCAGCCTATGGCTTGCCCTATGCTCT
  GTACACACAAGGGCAAGAAGGTCGTGGGTCGTACTCCCGGGAGGCCTACCACCTGCCCTTGCCTATGGCA
  GCCGAGCCCCTGCCCTCTTCCTCAGTCTCGGGAGAGGAGGCGCGGCTGCCTCATAGGGAGGAAGCAGAGA
  TAGCAGAAAGCAAGGTCCTACCATCAGCAGGCACAGTGGGTCGTGTGCTGGCTACCCTTGTCCAAGAGAT
  GAAGAGCATTATGCAGCGAGACCTTAATCGAAAGATGGTCGAGAATGTGGCCTTTGGAGCCTTTGACCAG
  TGGTGGGAGAGCAAGGAAGAGAAGGCCAAGCCATTCCAGAATGCAGCCAAACAGCAAGCCAAGGAAGAGG
  ACAAAGAAAAGATGAAGCTCAAAGAGCCAGGCATGCTGTCCCTCGTAGACTGGGCCAAGAGTGGCGGTAT
  CACAGGCATTGAGGCCTTTGCCTTTGGGTCAGGGCTTCGAGGGGCCCTGCGGTTGCCTTCATTCAAGGTA
  AAACGGAAAGAGCCATCAGAAATTTCAGAGGCAAGTGAGGAAAAGAGGCCCAGGCCCTCTACTCCAGCTG
  AGGAAGATGAAGATGATCCTGAGCGAGAGAAGGAAGCTGGAGAACCAGGACGTCCAGGGACCAAGCCTCC
  GAAGCGAGATGAAGAACGGGGCAAGACCCAAGGCAAACACCGAAAATCCTTTACTCTGGACAGTGAAGGG
  GAGGAGGCGTCCCAGGAGTCTTCCTCAGAGAAGGATGAGGATGATGATGATGAAGATGAGGAAGATGAAG
  AACAGGAGGAAGCTGTGGATGCCACCAAGAAGGAAGCAGAGGCATCGGATGGTGAGGATGAGGACAGTGA
  CTCGTCCTCCCAGTGCTCTCTGTATGCGGATTCAGATGGTGAAAATGGCAGCACATCAGACTCCGAGAGT
  GGCAGCTCGTCTTCCTCTTCCTCATCGTCTTCCTCCTCTTCCTCCTCTTCCTCATCAGAGTCCTCCTCTG
  AGGAAGAGGAGCAGTCAGCAGTCATTCCCTCAGCTTCACCCCCCAGAGAAGTTCCAGAGCCCCTTCCAGC
  TCCTGATGAGAAGCCTGAGACAGACGGGCTTGTAGATTCCCCTGTCATGCCTCTCTCTGAAAAGGAGACA
  TTGCCCACACAGCCTGCAGGCCCTGCTGAAGAACCACCTCCTAGTGTACCACAGCCTCCAGCAGAGCCAC
  CCGCCGGACCGCCAGACGCTGCCCCCCGCCTGGATGAGCGCCCCTCTTCTCCTATCCCTCTCCTACCCCC
  ACCCAAGAAACGCCGGAAAACTGTTTCCTTCTCTGCTGCAGAGGAGGCACCAGTCCCAGAACCTTCCACA
  GCTGCCCCACTGCAGGCCAAGTCTTCTGGTCCAGTCTCTCGAAAAGTCCCCCGGGTCGTAGAGCGGACCA
  TTCGTAACCTCCCCCTGGACCATGCGTCTCTGGTCAAGAGTTGGCCTGAGGAGGTCGCCCGAGGGGGTCG
  GAATCGAGCTGGAGGTCGTGTGCGCTCTACTGAAGAAGAGGAGGCCACTGAGTCAGGGACAGAAGTAGAC
  CTGGCAGTACTGGCTGACCTGGCCCTGACCCCAGCCCGACGTGGGTTGGCTACCCTACCCACTGGTGACG
  ACTCAGAGGCCACAGAGACCTCAGATGAGGCTGAGCGCCCAAGCCCTCTACTCAGCCACATCCTCTTGGA
  ACACAACTATGCCCTAGCCATCAAGCCCCCGCCTACCACACCAGCACCTCGGCCCCTGGAGCCAGCTCCT
  GCCCTTGCTGCACTCTTCAGCTCTCCAGCTGATGAAGTCTTAGAGGCCCCTGAGGTGGTGGTGGCTGAGG
  CAGAGGAGCCAAAGCAACAGCTGCAGCAGCAGCATCCAGAGCAGGAAGGAGAAGAGGAGGAGGAAGATGA
  AGAGGAGGAGTCCGAGTCTTCAGAAAGCAGCAGCAGCAGCAGCAGTGATGAGGAAGGGGCAATCAGGAGG
  CGTAGCCTCCGCTCCCACACTCGAAGAAGAAGGCCACCACTCCCACCCCCACCCCCACCTCCTCCTTCCT
  TTGAGCCGAGAAGTGAATTTGAGCAGATGACCATCTTGTATGATATTTGGAACTCAGGCCTTGACTTGGA
  AGACATGAGCTATTTGCGACTCACATATGAACGGCTGCTGCAGCAAACCAGTGGCGCTGACTGGCTTAAT
  GACACCCACTGGGTCCAGCACACAATCACCAACCTAAGCACTCCAAAGCGCAAAAGACGGCCCCAAGATG
  GGCCCCGGGAGCATCAGACAGGCTCTGCACGCAGCGAAGGTTATTACCCCATTAGCAAGAAGGAGAAAGA
  TAAATACTTGGATGTGTGCCCCGTCTCGGCCCGGCAGCTGGAAGGTGGAGACACTCAGGGGACTAATCGG
  GTGCTTTCTGAGCGACGGTCAGAGCAGCGGCGGTTACTAAGCGCTATTGGCACCTCAGCCATCATGGACA
  GTGATCTGCTAAAGCTAAACCAGCTCAAGTTTCGGAAGAAGAAACTCCGATTTGGCCGGAGCCGTATCCA
  TGAGTGGGGTCTGTTTGCCATGGAACCCATTGCCGCTGATGAGATGGTGATCGAATATGTTGGCCAGAAC
  ATCCGCCAGATGGTAGCGGACATGCGGGAAAAGCGCTACGTGCAGGAGGGCATTGGCAGCAGCTACCTTT
  TCCGGGTGGATCACGACACCATCATTGATGCCACCAAGTGTGGCAACCTCGCCAGGTTCATCAACCACTG
  CTGCACGCCCAACTGCTATGCGAAGGTGATCACCATTGAGTCTCAGAAAAAGATTGTCATCTACTCGAAG
  CAGCCCATCGGCGTGGATGAGGAGATCACCTACGACTACAAGTTCCCACTAGAAGACAACAAGATTCCGT
  GTCTGTGCGGCACTGAAAGTTGCCGTGGCTCCCTCAACTGA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_178029
• Insert Size: 5151 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_178029.3, NP_821172.2
• RefSeq Size: 5934 bp
• RefSeq ORF: 5151 bp
• Locus ID: 233904
• UniProt ID: E9PYH6
• Cytogenetics: 7 F3
• Gene Summary: Histone methyltransferase that specifically methylates 'Lys-4' of histone H3, when part of the SET1 histone methyltransferase (HMT) complex, but not if the neighboring 'Lys-9' residue is already methylated. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. The non-overlapping localization with SETD1B suggests that SETD1A and SETD1B make non-redundant contributions to the epigenetic control of chromatin structure and gene expression.[UniProtKB/Swiss-Prot Function]