Ltbp1 (NM_019919) Mouse Untagged Clone

CAT#: MC224864

Ltbp1 (untagged) - Mouse latent transforming growth factor beta binding protein 1 (Ltbp1), transcript variant 1, (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Ltbp1
• Synonyms: 9430031G15Rik; 9830146M04; b2b1000Clo; Ltbp-1; Ltbp1L; TGF-beta1-BP-1; Tgfb
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC224864 representing NM_019919
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGCGGGAGCCTGGCTCAGGTGGGGTCTCCTGCTCTGGGCAGGGCTGCTAGCGTGGTCTGCGCACGGCC
  GGGTGCGGAGGATCACGTACGTGGTGCGCCCGGGCCCGGGACTGCCGGCCGGAGCCTTGCCTCTGGCTGG
  GCCCCCGCGGACCTTCAACGTCGCACTGGACGCCAGGTACAGCCGGAGCTCAACAGCCGCCTCCAGCCGC
  GCCTTGGCTGGGCCCCCAGCCGAGCGGACCCGGCGCACCAGCCAGCCCGGCGGCGCGGCCCTGCCGGGGC
  TCCGATCTCCGCTGCCACCCGAGCCCGCGCGTCCGGGGGGGCCCAGCCGGCAGCTCCACTCTAAGGCGGG
  TGCTCAGACCGCGGTCACTCGCTTCGCCAAACATGGCAGGCAAGTCGTGCGCTCCCAAGTGCAGCAGGAC
  GCTCAGAGCGCCGGGGGCTCCAGACTGCAGGTTCAGCAGAAGCAGCAGCTGCAGGGGATCAACGTCTGTG
  GAGGGCAGTGCTGCCACGGGTGGAGTAAACCTCCTGGCTCCCAGAGGTGCACCAAACCCAGCTGTGTTCC
  GCCATGCCAGAACGGAGGGATGTGTCTACGGCCTCAGCTCTGTGTGTGCAAGCCAGGGTCAAAGGGCAAA
  GCCTGCGAGATCACAGCTGCCCAGGACACCATGCCGCCAGCCTTTGGAGGGCAGAATCCTGGGTCTTCGT
  GGGCCCCCCTTGAGCAAGCAGCAAAACATACGTCAACCAAGAAGGCAGACACCTTGCCCAGGGTCAGTCC
  AGTGGCCCAGATGACCTTGACCCTCAAGCCAAAGCCATCAATGGGACTCTCCCAGCAGATACATCCTCAA
  GTTGCACCCTTATCTTCCCAGAATGTGATGATTCGGCATGGCCAGACCCAGGAGTACCTGCTCAAACCCA
  AGTACTTCCCAGCCCCGAAGGTGGTCTCTGCGGAGCAATCCACCGAAGGCTCTTTCTCTTTAAGATATGG
  GCAGGAGCAAGGCACGGCACCCTTTCAGGTGAGTAACCACACTGGTCGCATCAAGGTGGTCTTTACTCCG
  AGCATCTGTAAAGTGACCTGCACCAAGGGCAACTGTCAGAACAGCTGCCAGAAGGGGAATACCACCACTC
  TCATTAGTGAGAACGGCCATGCAGCCGACACCCTGACAGCCACGAACTTCCGAGTGGTTATTTGCCATCT
  TCCGTGTATGAATGGTGGCCAGTGCAGTTCAAGGGACAAATGTCAGTGCCCTCCAAATTTCACAGGAAAG
  CTTTGCCAGATCCCTGTCCTTGGTGCCAGTATGCCCAAACTCTACCAGCACGCCCAGCAGCAGGGCAAGG
  CATTGGGGAGTCACGTCATCCATTCCACACATACCTTGCCTCTAACCATGACTAGCCAGCAAGGGGTCAA
  AGTGAAATTCCCCCCCAACATAGTCAATATCCATGTGAAACATCCTCCCGAGGCTTCTGTCCAGATACAC
  CAGGTTTCCAGGATTGACAGCCCAGGAGGCCAGAAGGTGAAGGAAGCCCAACCAGGCCAGTCCCAAGTCT
  CTTACCAAGGACTTCCGGTCCAGAAGACCCAGACAGTCCATTCTACGTACTCCCACCAGCAGCTTATTCC
  CCATGTGTATCCCGTGGCTGCTAAGACACAACTTGGCCGATGCTTCCAGGAAACCATTGGATCACAGTGT
  GGCAAAGCGCTCCCTGGCCTTTCCAAGCAAGAGGACTGCTGTGGGACAGTGGGGACGTCCTGGGGCTTTA
  ACAAATGCCAGAAGTGCCCCAAGAAACAATCCTATCATGGATATACTCAAATGATGGAATGCCTACAAGG
  ATATAAACGGGTTAACAACACCTTTTGTCAAGATATTAATGAATGTCAGCTACAAGGTGTATGCCCTAAT
  GGTGAGTGTTTGAATACCATGGGCAGCTACAGATGCTCCTGCAAAATGGGATTCGGGCCTGACCCTACCT
  TTTCAAGTTGTGTTCCGGATCCCCCTGTGATCTCAGAAGAGAAAGGGCCCTGTTACCGCCTTGTCAGTCC
  TGGAAGGCATTGTATGCACCCTCTCTCTGTTCATCTCACCAAGCAGATCTGCTGTTGTAGTGTGGGCAAG
  GCCTGGGGCCCACATTGTGAGAAATGTCCCCTCCCAGGCACAGCTGCTTTTAAGGAAATCTGTCCTGGTG
  GAATGGGTTATACGGTTTCTGGCGTTCATAGACGCAGGCCAATCCATCAGCATATAGGTAAAGAAGCTGT
  ATATGTCAAGCCAAAGAACACTCAACCTGTTGCTAAAAGTACTCATCCTCCACCTCTCCCAGCCAAGGAA
  GAGCCTGTGGAGGCCCTGACCTCCTCGTGGGAACACGGGCCGAGAGGGGCGGAGCCCGAAGTGGTAACAG
  CACCTCCTGAGAAGGAAATACCTTCACTGGATCAAGAGAAAACCAGACTTGAACCTGGGCAACCCCAGCT
  CTCCCCAGGGGTTTCAACTATTCATCTGCACCCACAGTTTCCAGTAGTGGTTGAAAAGACATCCCCTCCT
  GTGCCTGTGGAAGTAGCTCCTGAAGCTTCCACATCCAGTGCCAGCCAAGTGATTGCTCCTACGCAAGTAA
  CAGAAATCAACGAATGTACTGTGAACCCGGACATTTGCGGAGCAGGACACTGCATCAACCTGCCGGTGCG
  GTATACCTGCATATGCTACGAGGGCTACAAGTTCAGTGAACAGCTGAGGAAATGTGTCGACATTGATGAA
  TGTGCTCAGGTCCGGCACCTCTGCTCCCAGGGTCGCTGTGAGAACACAGAGGGAAGTTTCCTGTGTGTCT
  GCCCGGCAGGGTTTATGGCCAGTGAGGAGGGTACTAACTGTATAGATGTGGATGAGTGCCTGAGGCCTGA
  TATGTGTAGGGATGGCCGCTGCATCAACACCGCTGGGGCCTTCCGGTGCGAGTACTGTGACAGTGGGTAC
  CGGATGTCACGGAGAGGCTACTGTGAGGATATTGATGAGTGTCTGAAGCCAAGCACTTGTCCCGAGGAAC
  AGTGTGTGAACACCCCGGGCTCTTACCAGTGTGTGCCCTGCACAGAGGGGTTCCGCGGCTGGAATGGACA
  ATGCCTTGATGTGGACGAGTGCCTGCAGCCAAAGGTCTGTACGAATGGTTCCTGCACCAACCTGGAAGGG
  TCCTACATGTGTTCCTGCCACAGGGGCTACAGCCCCACACCAGACCATAGACACTGTCAAGATATTGATG
  AATGCCAACAAGGGAATCTCTGCATGAATGGGCAGTGCAGAAATACCGATGGCTCCTTCCGGTGTACCTG
  TGGACAGGGCTATCAGCTGTCAGCAGCTAAAGACCAATGTGAAGATATTGATGAATGCGAGCACCATCAC
  CTCTGCTCTCACGGGCAGTGCAGGAACACAGAGGGCTCCTTCCAGTGTGTGTGCAACCAGGGTTACAGAG
  CATCTGTACTTGGAGACCACTGTGAGGATATCAATGAATGCTTGGAGGACAGCAGTGTCTGCCAGGGAGG
  TGACTGCATCAATACTGCGGGGTCCTATGATTGCACATGCCCGGATGGATTCCAGCTGAACGACAATAAG
  GGCTGTCAAGACATTAATGAATGTGCACAGCCAGGACTCTGTGGATCTCATGGGGAGTGTCTAAACACAC
  AAGGCTCCTTCCACTGTGTCTGTGAACAGGGGTTCTCCATCTCTGCCGATGGCCGTACATGCGAAGATAT
  TGATGAGTGTGTTAACAACACTGTGTGTGACAGTCACGGCTTCTGTGACAACACAGCCGGCTCTTTCCGC
  TGCCTCTGTTATCAGGGCTTTCAAGCCCCACAGGATGGGCAAGGGTGTGTGGATGTGAACGAGTGTGAAC
  TGCTCAGTGGTGTATGTGGGGAAGCCTTCTGTGAAAACGTGGAAGGATCCTTCCTGTGTGTGTGTGCCGA
  TGAGAACCAGGAGTACAGCCCCATGACTGGGCAGTGTCGCTCTCGGGTCACGGAAGATTCAGGTGTGGAT
  CGTCAGCCTAGAGAAGAGAAGAAGGAGTGCTATTATAACCTCAATGATGCTAGTCTCTGTGATAATGTCC
  TGGCCCCCAACGTCACCAAACAAGAGTGCTGCTGTACGTCAGGTGCCGGCTGGGGAGACAACTGTGAGAT
  CTTCCCTTGCCCCGTCCAGGGAACTGCTGAGTTCACGGAAATGTGCCCTAGAGGGAAAGGTTTGGTCCCG
  GCTGGAGAATCCTCTTACGACACTGGTGGCGAGAACTACAAAGATGCTGATGAATGCTTGCTGTTTGGAG
  AGGAAATCTGTAAAAATGGTTACTGTTTGAACACTCAACCTGGGTATGAATGCTACTGTAAGCAAGGGAC
  ATACTATGATCCTGTCAAATTACAGTGCTTTGATATGGATGAATGCCAAGACCCTAACAGTTGCATTGAC
  GGCCAGTGTGTGAACACAGAGGGCTCCTACAACTGCTTTTGCACCCACCCAATGGTCCTGGATGCCTCTG
  AGAAGAGATGTGTGCAACCAACTGAATCAAATGAACAAATAGAAGAGACCGATGTCTATCAAGATCTGTG
  CTGGGAGCATCTGAGTGAGGAGTACGTGTGTAGCCGTCCTCTCGTAGGCAAGCAGACGACGTACACAGAA
  TGCTGCTGTTTGTACGGGGAGGCTTGGGGCATGCAGTGTGCTCTGTGCCCCATGAAGGACTCAGATGACT
  ATGCCCAGCTGTGCAATATCCCTGTGACTGGGCGTCGGCGGCCATATGGACGGGATGCATTGGTGGACTT
  CAGTGAACAGTATGGCCCAGAAACAGACCCTTACTTCATCCAGGATCGCTTTCTAAATAGCTTTGAGGAG
  CTACAGGCTGAGGAGTGTGGCATCCTCAATGGTTGTGAAAACGGCCGCTGTGTGAGAGTCCAGGAAGGAT
  ACACTTGCGATTGCTTTGATGGATATCACCTGGATATGGCCAAGATGACCTGTGTCGATGTAAATGAATG
  CAGCGAGCTGAATAATCGGATGTCTCTCTGCAAGAACGCCAAGTGCATTAACACAGAAGGCTCCTACAAA
  TGCTTGTGTCTGCCAGGCTACATACCATCCGACAAGCCCAACTACTGTACACCCCTGAACAGCGCTTTGA
  ATTTAGACAAAGAAAGTGACCTGGAGTGA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_019919
• Insert Size: 5139 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_019919.3, NP_064303.2
• RefSeq Size: 7910 bp
• RefSeq ORF: 5139 bp
• Locus ID: 268977
• UniProt ID: Q8CG19
• Cytogenetics: 17 E2
• Gene Summary: Key regulator of transforming growth factor beta (TGFB1, TGFB2 and TGFB3) that controls TGF-beta activation by maintaining it in a latent state during storage in extracellular space. Associates specifically via disulfide bonds with the Latency-associated peptide (LAP), which is the regulatory chain of TGF-beta, and regulates integrin-dependent activation of TGF-beta. Outcompeted by LRRC32/GARP for binding to LAP regulatory chain of TGF-beta.[UniProtKB/Swiss-Prot Function]
  Transcript Variant: This variant (1) is the longest transcript and it encodes the longest isoform (LTBP-1L). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.