Ltbp4 (NM_175641) Mouse Untagged Clone

CAT#: MC224801

Ltbp4 (untagged) - Mouse latent transforming growth factor beta binding protein 4 (Ltbp4), transcript variant 1, (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Ltbp4
• Synonyms: 2310046A13Rik
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC224801 representing NM_175641.
  Blue=ORF Red=Cloning site Green=Tag(s)
  
  GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG
  GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC
  ATGCGCCGGCCTGGCCTCGGCGGCCCCTGCCCCCTCTTGCTGCTGCTGCTGCTCCCAGCCGCCACATCT
  GCTAGCGGCTCCAGTCCCAGCCCCAGCCCCAGCCCCATCGAGAAAGCGGTGGTCCCGAGCCACCAGGCC
  GGTGTTGCTGCCTGTCACTGCTGCCTAGACCAGACACCTAAGAGTAGCCGCTGCACCCGAGCTTCCTGC
  AGGGTCCGGAACTGCCCACCTGCCAAGTGCACAGGTCTAGAGGGGTGCCTGACCCCAACACCTTCGGTG
  CCCAGCCCCAGCCGCAGTCCCGTGGAGAAGAGTCAGGTATCCCTCAACTGGCAGCCACTGACTTTGCAG
  GAGGCCCGAGCTCTGCTGAGGCAAAGGCGGCCCCGAGGGCCGTGGGCCCGGGCATTGCTGAAAAGAAGG
  CCCCCACATCGCGCCCCTGCCGGCCAGGCCCGGGTCCTATGTCCCTTGATCTGTCACAACGGTGGTGTG
  TGTGTGAAGCCTGATCGCTGCCTTTGCCCCCCGGACTTCGCTGGCAAATTCTGCCAATTGCATTCTTCG
  GGGGCCCGGCCCCCGGCCCCAGCCATGCCGGGCCTTACCCGCTCCGTTTATACAATGCCACTAGCCAAC
  CACCGCGATGATGAACACGGAGTAGCATCGATGGTGAGCGTGCACGTGGAGCACCCTCAGGAGGCATCA
  GTGGTGGTGCACCAAGTGGAACGTGTGTCGGGCCCCTGGGAGGAGGCGAACCCTGAAGCCCTAGCCAGG
  GCTGAAGCGGCGGCACGGGCCGAGGCGGCGGCGCCCTACACAGTGCTGGCACAGAGCGCGCCACGCGAG
  GACGGCTACTCAGACGCCTCCGGCTTCGGTTACTGTTTTAGAGAACTGCGCGGAAGCGAATGTGCATCG
  CCGCTGCCAGGGCTCCGGACGCAGGAAGTCTGCTGCCGAGGAGAGGGCTTGGCCTGGGGTGTTCATGAT
  TGTCACCCGTGCGCGGAACACCTGAGGAACTCCAACCAAGTGAGTGGCCCAAATGGACCTTGTCCACCC
  GGCTTCGAGAGAGTTAATGGGTCCTGTGTAGATGTGGATGAGTGCGCCACCGGTGGGCGTTGCCAACAC
  GGGGAGTGTGCCAACACTCGTGGCGGCTACACGTGTGTATGTCCGGACGGTTTCCTCCTGGACTCTTCC
  CGCAGCAGCTGCATCTCCCAACACGTGATCTCCGAGGCAAAGGGGCCCTGCTACCGAGTGCTGCATGAT
  GGCGGATGCTCGCTGCCCATTCTTCGAAATATCACCAAACAGATCTGCTGCTGTAGCCGTGTGGGCAAG
  GCGTGGGGCCGAGGCTGCCAGCTCTGTCCACCTTATGGTTCAGAGGGTTTTCGGGAGATCTGTCCAGCT
  GGCCCTGGCTACCACTATTCAGCTTCTGACCTCCGATACAACACCAGACCCCTAAACCAGGATCCACCT
  CGAGTGACCTTCAATCAGCCACGTGTTCCACCAGCCACCCCTCGGCCACCTACAGGCTTTCTGCCTACT
  CGTCGACCTGAGCCCCGCCCTGACCCTGGGCCACAGCCTGAACCCCGGCCTCGGCCTGAACCCCGGCCT
  CGGCCTGAATCCCGACCTCGGCCTGAACCCCGGCCTCGGCCTGAACCCCGGCCTCAGCCTGAATCCCAG
  CCTAGGCCTGAATCCCGGCCTCGGCCTGAATCCCAGCCTTGGCCTGAATTTCCCCTGCCCAGCATCCCT
  GCTTGGACCGGTCCAGAGATTCCTGAATCAGGTCCCTCTTCCAGCATGTGTCAGCGAAATCCCCAGGTT
  TGTGGTCCTGGACGCTGCGTTCCTAGGCCAAGCGGCTACACTTGTGCGTGCGACCCAGGTTTCCGGCTC
  GGCCCCCAGGGCACTCGCTGCATTGACATAGATGAATGTCGCCGCGTCCCTACACCCTGTGCTCCTGGG
  CGTTGCGAGAATACACCAGGCAGCTTTCGCTGCGTGTGCGGCACGGGCTTCCAAGCAGGCCCGCGGGCT
  ACAGAGTGCCTGGATGTGGACGAGTGCCGCCGCGTGCCGCCGCCGTGTGACCGCGGGCGCTGCGAGAAC
  ACGCCAGGCAGTTTCCTATGTGTGTGTCCCGCCGGGTACCAGGCAGCACCGCACGGAGCCAGCTGCCAG
  GATGTGGATGAATGCACCCAGAGCCCAGGCCTCTGTGGTCGCGGGGTCTGCGAAAACCTGCCCGGCTCT
  TTCCGCTGTGTTTGCCCGGCTGGCTTCCGGGGCTCGGCGTGTGAAGAAGATGTGGATGAATGTGCCCAG
  CAGCCTCCGCCTTGCGGGCCAGGCCGCTGCGACAACACCGCGGGTTCGTTCCACTGTGCCTGCCCAGCT
  GGCTTCCGATCCCGAGGACCAGGAGCCCCCTGCCAAGATGTGGATGAATGTTCCCGGAGCCCCTCGCCT
  TGTGCCTATGGCCGCTGTGAGAACACGGAAGGCAGCTTCAAGTGTGTCTGCCCAACAGGCTTCCAACCC
  AACGCTGCGGGCTCCGAGTGCGAGGATGTGGATGAGTGTGAGAACCGCTTGGCGTGTCCAGGGCAGGAG
  TGTGTGAACTCACCGGGCTCCTTCCAGTGCCGGGCCTGCCCTGTTGGGCACCACCTGCACCGTGGCAGA
  TGTACTGATGTGGATGAATGCAGTTCGGGCACCCCTTGTGGTCTCCATGGCCAGTGCACAAATACTAAA
  GGCTCCTTCCACTGCAGCTGCTCGACAGGTTACCGGGCGCCATCTGGTCAACCTGGGCCTTGTGCAGAC
  ATAAATGAGTGTCTGGAAGGCGACTTCTGCTTCCCCCACGGAGAGTGCCTCAACACTGATGGCTCCTTT
  ACCTGTACCTGTGCCCCTGGCTACCGGCCTGGACCTCGTGGAGCATCTTGTCTGGACGTGGACGAGTGC
  AGCGAAGAGGATCTTTGCCAGAGCGGCATCTGTACCAACACTGACGGCTCCTTCGAGTGCATCTGTCCT
  CCTGGACACCGCGCTGGCCCTGACCTTGCCTCCTGCCTTGACATTGACGAGTGTCGTGAACGGGGACCT
  GCCCTGTGCGGGTCTCAGCGCTGTGAAAATTCTCCTGGTTCCTACCGCTGTGTGCGGGACTGCGATCCA
  GGTTACCACCCCGGCCCTGAGGGCACCTGTGATGACATTGATGAGTGCCGAGAATACGGCTCTGCGATT
  TGTGGTGCCCAGCGCTGTGAGAACACCCCGGGCTCCTACCGCTGCACACCAGCCTGCGACCCTGGCTAT
  CAGCCTACACCAGGGGGCGGGTGCCAAGATGTGGATGAATGCCGGAACCGGTCTTTCTGCGGCGCCCAT
  GCTATGTGCCAGAATCTGCCTGGGTCCTTTCAGTGCGTCTGTGACCAAGGCTACGAAGGGGCACGGGAC
  GGACGTCACTGCGTGGATGTGAATGAGTGTGAGACACTACAGGGCGTGTGTGGCTCCGCGCTGTGTGAA
  AATGTTGAAGGCTCCTTCCTGTGTGTCTGCCCCAATAGCCCTGAGGAATTTGATCCCATGACTGGACGC
  TGTGTTCCCCCACGGGCTCCTGCAGGCACGTTCCCTGGCTCCCAGCCCCAAGCACCTGCCAGCCCCAGT
  CTTCCAGCCAGGCCACCAGCCCCTCCCCCACCTCGAAGACCCAGCCCTCCCAGGCAGGGTCCCGTGAGC
  AGTGGACGTCGCGAGTGCTACTTTGATACAGCCGCTCCAGATGCGTGTGACAATATCTTGGCCCGAAAC
  GTGACGTGGCAGGAGTGCTGCTGTACTGTGGGAGAAGGCTGGGGCAGCGGCTGCCGCATCCAACAGTGC
  CCGGGCACCGAGACAGCTGAATACCAGTCATTGTGTCCTCACGGCCGGGGCTACCTGGTGCCCAGTGGA
  GACCTGAGTGCCCGGAGAGATGTGGACGAATGCCAACTCTTCCAGGACCAGGTGTGCAAGAGCGGAGTG
  TGTGTGAACACGGCCCCAGGCTACTCTTGCTATTGCAGCAACGGGTTCTACTATCACGCACACAGGCTG
  GAGTGCGTTGATAATGACGAATGTGCGGACGAGGAGCCTGCTTGTGAAGGTGGCCGCTGCGTCAACACG
  GTGGGCTCTTACCACTGTACCTGCGAGCCCCCACTGGTGCTGGACGGCTCCCGGCGACGCTGCGTCTCC
  AACGAGAGCCAGAGCCTGGATGACAATCTAGGAGTGTGCTGGCAGGAAGTGGGACCTGATCTCGTCTGC
  AGTCGCCCACGACTAGACCGGCAGGCCACCTACACCGAGTGCTGCTGTCTCTATGGTGAAGCCTGGGGT
  ATGGACTGCGCTCTCTGTCCTGCCCAGGACTCAGATGACTTTGAGGCCCTTTGCAATGTGCTGCGTCCA
  CCTGCCTATGGCCCGCCGCGCCCTGGTGGCTTTGGAATTCCCTATGAATATGGCCCAGATATAGGCCCA
  CCTTATCAGAGTCTCCCCTATGGGCCAGATCTGTATCCACCGCCAGTGCTACCCTACGACCCCTACCCA
  CCCCCACCTGGACCCTTTGCTCGCCGGGAGGCCCCTTATGGCGCCCCACCCTTCGACATGCCGGACTTT
  GAGGATGATGGTGGCCCCTATGGCGAGTCTGAGACTCCTGACCCACCTAGCCGAGGCACTGGTTGGCCT
  TATCGGTCCAGAGACACCCGTGGCTCCTTCCCAGAGCCTGAGGAATCCTCTGAGCGTGGAAGCTATACA
  GGAGCCTTGTCTGAGCCCTATGAGGGCCTAGAGGCCGAAGAGTGTGGTATCCTGGATGGCTGCCCTCAC
  GGCCGCTGTGTGCGCGTTCCAGAAGGCTTCACCTGCGATTGTTTCGATGGCTACCGCCTGGACATCACC
  CGCATGTCCTGTGTCGACGTCAACGAGTGTGATGAGGCAGAGGCAACCTCCCCACTCTGCGTCAATGCG
  CGCTGTGTCAACACTGACGGCTCCTTCCGCTGTATCTGTCGTCCAGGATTTGCTCCCACGCATCAGCCA
  CATCACTGTGCGCCTGCTCGACCCCGGGCCTGA
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT
  TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_175641
• Insert Size: 5001 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_175641.2
• RefSeq Size: 5322 bp
• RefSeq ORF: 5001 bp
• Locus ID: 108075
• UniProt ID: Q8K4G1
• Cytogenetics: 7 A3
• MW: 178.6 kDa
• Gene Summary: Key regulator of transforming growth factor beta (TGFB1, TGFB2 and TGFB3) that controls TGF-beta activation by maintaining it in a latent state during storage in extracellular space. Associates specifically via disulfide bonds with the Latency-associated peptide (LAP), which is the regulatory chain of TGF-beta, and regulates integrin-dependent activation of TGF-beta.[UniProtKB/Swiss-Prot Function]
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a).