Rb1cc1 (NM_009826) Mouse Untagged Clone

CAT#: MC224720

Rb1cc1 (untagged) - Mouse RB1-inducible coiled-coil 1 (Rb1cc1), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Rb1cc1
• Synonyms: 2900055E04Rik; 5930404L04Rik; Cc1; FIP200; LaXp180
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_009826, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGAAGTTATATGTGTTTCTGGTTAACACCGGAACCACGCTGACATTTGACACTGAGCTAACTGTGCAAA
  CTGTGGCTGATCTTAAGCATGCCATTCAAAGCAAATACAAGATTGCTATTCAGCACCAGGTTCTGGTGGT
  CAATGGAGGAGAATGCATGGCTGCAGATCGAAGAGTGTGTACTTACAGCGCTGGGACGGACACAAATCCA
  ATTTTTCTTTTTAATAAAGAAATGATCTTATGTGACCGTGCACCTGCTATTCCTAAAGCTACCTTTTCAA
  CAGAAAATGACATGGAAATAAAAGTTGAAGAGTCTCTTATGATGCCTGCAGTTTTCCACACTGTTGCTTC
  AAGGACACAGCTTGCAGTGGAAATGTATGACGTTGCCAAGAAGCTCTGCTCTTTCTGTGAAGGGCTTGTC
  CATGATGAACATCTTCAGCACCAAGGCTGGGCTGCAATCATGGCCAATCTGGAGGACTGTTCAAATTCAT
  ACCAAAAACTTCTTTTCAAGTTTGAAAGTATTTATTCTGATTATCTTCAATCCATAGAAGACATCAAGTT
  AAAACTTACTCATTTAGGAACTGCTGTTTCAGTAATGGCCAAGATTCCACTATTGGAGTGCCTAACCAGA
  CATAGTTACAGGGAATGTTTGGGAAGACCGGATTCTTTGAATGAACATGAAGGCTCAGAGAAAGCTGAGA
  TGAAAAGATCTACTGAATTGGTGCTCTCTCCTGATATGCCTAGAACATCGAACACATCCTTGGTAACCTC
  ATTTCACAAGTCAATGGAGCATGTAGCTCCAGATCCCACCGGTACTGAACGTGGCAAAGAACTTAGGGAA
  TCTTGTCAAAGTACTGTCCAGCAAGAAGAAGCTTCAGTGGATGCTAAAGACAGTGATCTGCCTTTTTTTA
  ATGTTTCTTTGTTAGACTGGATAAATGTTCAAGATAGACCCAATGATGTGGAATCTCTGGTCAGGAAGTG
  CTTTGATTCTATGAGCAGGCTTGACCCAAAGATTATTCAACCATTTATGTTAGAATGCCATCAAACTATT
  GCCAAACTTGATAATCAGAATATGAAAGCCATTAAAGGGCTTGAAGATCGGCTGTATGCCTTGGACCAGA
  TGATTGCTAGCTGTAGCCGGCTGGTAAATGAACAGAAAGAGCTTGCTCAGGGATTTTTAGCTAATCAGAT
  GAGAGCTGAAAACTTGAAGGATGCATCTGTGTTACCTGATCTGTGTCTGAGTCATGCAAATCAACTAATG
  ATTATGTTGCAAAACCACAGAAAACTGTTGGATATTAAACAGAAGTGCACCACTGCCAAACAAGAGCTAG
  CAAACAATCTCCACGTCAGACTGAAGTGGTGTTGTTTTGTGATGCTTCATGCTGATCAAGATGGAGAAAA
  ACTGCAGGCACTGCTCCGCCTTGTAATAGAGCTGTTAGAAAGAGTCAGAATTGTTGAGGCTCTTAGTACA
  GTTCCTCAGATGTATTGCCTAGCTGTTGTTGAGGTTGTAAGAAGAAAAATGTTCATTAAACACTACAGAG
  AGTGGGCTGGTGCTTTAGTCAAAGACGGAAAACAACTATATGAAGCTGAAAAGTCAAAAAGGGAATCCTT
  TGGGAAATTATTTAGGAAGTCCTTTTTAAGAAATCGTCTGTTTAAAGGACTGGACTCCTGGCCTTCCTCA
  TTTTGTACTCAGAAGCCTCGAAAATTTGACTGTGAACTTCCAGATATATCGTTAAAAGATTTACAGTTTC
  TTCAATCATTTTGTCCTTCAGAAGTGCAGCCATTCCTCAGGGTCCCCTTACTTTGTGACTTTGAACCTCT
  ACACCAGCATGTACTTGCCCTACATAATTTGGTAAAAGCAGCACAAAGTTTGGATGAAATGTCACAGACT
  ATTACAGATCTCCTAAATGAACAAAAGGTATCCACAAGTCAGGCATCCCCACAGTCAGCTGCTTCTCCAA
  GAATAGAAAGTACAACAGGCATTACAACCACTACCTCACCAAAAACTCCTCCTCCACTAACTGTTCAGGA
  CACCTTATGTCCGGCAGTGTGTCCCTTAGAAGAATTATCTCCAGATAGTATCGATGCTCATACATTTGAT
  TTTGAAACCATCTCCCATCCAAACACAGAACAACCTGTTCACCAAGCTTCTATAGACTTGGATTCATTAG
  CAGAAAGCCCTGAGTCTGACTTTATGTCTGCTGTGAATGAGTTTGTGATAGAAGAAAATTTATCGTCTCC
  AAACCCTATAAGTGATCCACAAAGTCCAGAAATGATGGTGGAGTCACTTTACTCTTCAGTCATCAATGCA
  ATAGATAGTAGGCGTATGCAAGACACAAGTACACGTGGAAACGAGGGCTTTGGGGATCGGGCTGCTCTAC
  ATGTCCAGCTGGAGAAATGCAGAGCTGCTGCACAAGACTCTCACAGCAGTATACAAACCATCAAGGACGA
  TCTGTGCCATTTCAGAACATTTGTACAAAAAGAACAGTGTGACTTAGCAAATTATTTAAAATGTACAGCT
  GTAGAAATAAGAAATATTATTGAAAAAGTAAAATGTTCTCTAGAAATAACACTAAAGGAAAAGCATCAGC
  AAGAACTCCAATCTTTAAAAATTGAGTATGAATGTAAACTTGATGCTCTAGTAAAAGACAGTGAAGAAAA
  TGTAAATAAAATTTTAAAATTGAAAGAAAATTTAGTATCCCTTGAAGAGGCTTTACAAAATAAAGACAAT
  GAATTCACTTCGATTAAACATGAAAAGGATGCTATTGTCTGTGTGCAGCAAGAAAAGGATCAGAAGTTGT
  TAGAGATGGAAAAGATAATGCATACTCAACATTGTGAAATTAAAGAACTGAAGCAGTCACGAGAGATGGC
  ATTAGAAGACCTGAAAAAGCTGCATGATGAAAAAATCGAGTCATTGAGAGCTGAATTTCAGTGCTTAGAA
  CAAAATCACCTGAAGGAATTAGAGGACACACTGCACATCAGGCACACACAGGAGTTTGAGAAAGTTATGA
  CAGACCACAATATGTCTTTGGAGAAATTAAAAAAAGAAAATCAGCAAAGAATTGACCAGATGCTAGAATC
  TCATGCCTCAACTATTCAGGAAAAAGAGCAACAGCTGCAGGAGTTGAAACTCAAAGTTTCTGACTTGTCA
  GACATGAGATGTAAGTTAGAGGTTGAACTTGCACTAAAGGAAGCAGAAACAGATGAGATAAAGATCTTGT
  TGGAAGAGAGCAGAACACAGCAGAAGGAAATGCTGAAGTCTTTACTTGAACAAGAGACCGAAAACTTAAG
  AACAGAAATAAGTAAACTAAACCAAAAAATTCATGATAATAATGAGAGTTACCAGGTGGGTTTGTCAGAG
  TTAAGAGCTTTAATGACAATTGAAAAAGATCAGTGCATTTCAGAGTTAATCAGTAGACATGAAGAAGAAT
  CTAATATACTTAAGGCTGAATTAGACAATGTTACATCTTTGCATCGCCAAGCATTTGAAATAGAAAAAAA
  ACTGAAAGAACAAATAGTTGAATTGCAGACTAGATTGAACTCAGAATTGAGTGCTCTTGAAAAACAGAAA
  GATGAAAAAATAACCCAACAAGAAGAGAAGTATGAAGCACGTATCCAGAACCTTGAGAAAGACAAGGAGA
  GACTGGTCAAGAACCACGAGCAAGACAAAGAACACTTAATTCAGGAGCTTAATTTTGAAAAAAACAAAGC
  TGTTCAAACTGCACTAGATGAATTTAAGGTGGAGAGAGAACTTGTTGAGAAAGAGTTATTAGAAAAAGTT
  AAACATCTTGAGAATCAAATAGCCAAAACTCCTGCCTTTGAGTCAGCCAGAGAAGATTCTTCAAGCTTAG
  TTGCGGAACTTCAAGAGAAACTTCAAGAAGAAAAAGCTAAGTTTCTGGAACAACTTGAAGAACAAGAGAA
  AAGAAAGAATGAGGAAATGCAAAATGTCAGAACCTCTTTGATTGCTGAGCAGCAGACCAACTTTAACACA
  GTCTTAACAAGAGAGAAAATGAGGAAAGAAAACATAATAAATGATCTTAGTGATAAGCTAAAAAGTACAA
  TGCAGCAGCAAGAGCGGGATAAAGATTTGATAGAGTCGCTCTCTGAGGACCGAGCTCGTTTGCTTGAAGA
  GAAGAAGCAGCTTGAAGAGGAAGTGAGTAAACTCCGCACTAGCAGTTTTCTTTCCTCAGCACCTGTGGCT
  GCAGCCCCAGAGCTCTATGGTGCGTGTGCACCTGAGCTCCCAGGGGAGCCAGAGAGATCAGTCATGGAGA
  CGGCAGATGAAGGAAGACTGGATTCCGCAATGGAGACAAGCATGATGTCTGTCCAAGAAAACATGTTATC
  TGAAGAGAAGCAGAGGATCATGCTCCTAGAACGGACATTGCAGTTGAAAGAAGAAGAAAACAAGCGGTTA
  AATCAAAGACTGATGTCTCAGAGTTTGTCCTCAGTCTCTTCAAGGCATTCTGAAAAAATAGCCATTAGAG
  ATTTTCAGGTGGGAGATTTGGTTCTCATCATCCTAGATGAGCGGCACGACAATTATGTATTGTTTACTGT
  TAGTCCTACTTTATATTTTCTGCACTCAGAGTCTCTTCCTGCCCTGGATCTCAAACCAGGTGAGGGAGCT
  TCAGGTGCATCTAGAAGACCCTGGGTCCTTGGGAAAGTAATGGAAAAGGAATACTGTCAAGCCAAAAAGG
  CACAAAACAGATTTAAAGTTCCTTTGGGGACAAAGTTTTACAGAGTGAAAGCTGTGTCATGGAATAAGAA
  AGTATAG
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_009826
• Insert Size: 4767 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC150774, AAI50775
• RefSeq Size: 5132 bp
• RefSeq ORF: 4767 bp
• Locus ID: 12421
• UniProt ID: Q9ESK9
• Cytogenetics: 1 A1
• Gene Summary: Involved in autophagy (PubMed:23262492, PubMed:19258318). Regulates early events but also late events of autophagosome formation through direct interaction with Atg16L1 (PubMed:23392225, PubMed:23285000, PubMed:19258318). Required for the formation of the autophagosome-like double-membrane structure that surrounds the Salmonella-containing vacuole (SCV) during S.typhimurium infection and subsequent xenophagy (PubMed:21525242). Involved in repair of DNA damage caused by ionizing radiation, which subsequently improves cell survival by decreasing apoptosis (PubMed:21807966). Inhibits PTK2/FAK1 and PTK2B/PYK2 kinase activity, affecting their downstream signaling pathways (By similarity). Plays a role as a modulator of TGF-beta-signaling by restricting substrate specificity of RNF111 (PubMed:21795712). Functions as a DNA-binding transcription factor (PubMed:12095676). Is a potent regulator of the RB1 pathway through induction of RB1 expression (PubMed:15968549). Plays a crucial role in muscular differentiation (PubMed:15968549). Plays an indispensable role in fetal hematopoiesis and in the regulation of neuronal homeostasis (PubMed:19940130, PubMed:21088496).[UniProtKB/Swiss-Prot Function]