Adgrb1 (NM_174991) Mouse Untagged Clone

CAT#: MC224714

Bai1 (untagged) - Mouse brain-specific angiogenesis inhibitor 1 (Bai1), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Adgrb1
• Synonyms: B830018M07Rik; Bai1; mKIAA4089; R75078
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC224714 representing NM_174991
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGAGGGGCCAGGCTGCTGCCCCGGGCCCCATCTGGATCCTTGCTCCACTCCTGCTGTTACTATTGCTAT
  TGGGGCGCTGGGCGCGCGCTGCCTCTGGGGCAGACATAGGGCCTGGGACAGAGCAGTGCACCACGTTGGT
  GCAGGGAAAGTTCTTCGGCTACTTCTCGGCGGCTGCTGTATTTCCGGCCAACGCCTCACGCTGCTCTTGG
  ACCCTTCGCAACCCGGACCCTCGTCGTTACACGCTCTACATGAAGGTGGCCAAGGCACCTGCACCCTGCA
  GCGGCCCCGGCCGAGTTCGTACCTACCAGTTCGACTCTTTCTTGGAGTCTACACGCACCTACCTGGGTGT
  GGAGAGCTTTGACGAAGTTCTGCGGCTCTGCGATTCCTCTGCACCCCTCGCCTTTCTACAGGCCAGCAAA
  CAGTTTCTACAGATGCAACGCCAACAGCCACCCCAAGACGGTGACCTCGGACCCCAGGGCGAGTTCCCCA
  GCTCTAGTGACGACTTCTCCGTGGAGTACCTGGTGGTGGGCAATCGCAACCCCAGCCATGCTGCCTGTCA
  GATGCTGTGTCGCTGGCTGGATGCCTGTCTAGCCGGCAGCCGCAGCTCACACCCCTGTGGCATCATGCAG
  ACTCCCTGCGCCTGCCTGGGTGGAGATGTTGGAGACCCTGCTTCCAGCCCCTTGGTCCCCCGTGGGGACG
  TCTGCTTGAGGGACGGCGTAGCTGGTGGCCCTGAGAACTGCCTCACCAGCCTGACCCAGGACCGGGGTGG
  GCACGGCTCAGCAGGTGGCTGGAAACTGTGGTCCTTGTGGGGCGAATGTACGCGGGACTGCGGGGGAGGC
  CTGCAAACTCGAACCCGCACTTGCTTACCCACCCTTGGTGTGGAGGGCGGAGGCTGCGAGGGCGTTCTGG
  AAGAAGGTCGCCTGTGCAATCGCAAGGCCTGCGGTCCCACTGGGCGCAGCAGCTCACGGAGCCAGTCCCT
  GAGGTCCACGGATGCCCGGCGACGTGAGGAGTTTGGGGATGAGCTGCAGCAGTTTGGGTTCCCATCTCCC
  CAGACTGGTGACCCAGCAGCTGAGGAGTGGTCCCCATGGAGTGTATGCTCCAGTACCTGCGGTGAGGGCT
  GGCAGACCCGCACCCGCTTCTGCGTGTCATCCTCGTACAGTACTCAGTGCAGTGGACCTCTGAGGGAGCA
  GCGGCTCTGCAACAACTCAGCCGTGTGTCCAGTGCATGGAGCCTGGGATGAGTGGTCACCCTGGAGCCTC
  TGCTCCAGCACCTGTGGCCGTGGCTTCCGTGACCGCACTCGCACCTGCAGGCCCCCTCAGTTTGGAGGCA
  ACCCCTGTGAGGGTCCTGAGAAGCAAACCAAGTTCTGCAACATTGCTCTGTGCCCTGGCCGGGCAGTGGA
  TGGAAACTGGAACGAATGGTCCAGCTGGAGCACCTGCTCTGCCAGTTGCTCCCAAGGCCGCCAGCAGCGG
  ACCCGAGAGTGCAATGGTCCTTCCTATGGAGGCGCTGAGTGCCAGGGCCACTGGGTGGAGACTCGAGACT
  GCTTCCTGCAGCAATGCCCAGTGGATGGCAAATGGCAGGCCTGGGCCTCATGGGGCAGCTGCAGCGTCAC
  ATGTGGAGGTGGAAGCCAGCGACGGGAGCGTGTCTGCTCTGGGCCTTTCTTTGGGGGAGCAGCCTGCCAG
  GGGCCCCAGGACGAGTACCGACAGTGTGGCGCTCAACGATGTCCTGAGCCCCATGAGATTTGTGATGAGG
  ACAACTTTGGGGCCGTGGTCTGGAAGGAGACCCCAGCTGGAGAGGTGGCTGCAGTCCGGTGTCCCCGCAA
  TGCCACAGGCCTCATCCTGCGCCGCTGTGAGCTGGACGAGGAGGGCATCGCCTTCTGGGAGCCGCCCACC
  TACATCCGCTGCGTCTCCATCGACTACCGGAACATCCAGATGATGACCCGAGAACACCTGGCAAAGGCTC
  AGCGGGGGCTGCCAGGGGAGGGGGTCTCAGAGGTCATCCAGACACTGCTGGAGATCTCACAGGATGGCAC
  CAGCTACAGCGGCGACCTGCTCTCCACCATTGATGTCCTGAGGAACATGACAGAGATTTTCCGCAGGGCT
  TACTACAGCCCCACGCCAGGGGATGTGCAGAACTTTGTCCAGATCATCAGCAACCTGCTGGCAGAAGAGA
  ACCGGGACAAGTGGGAGGAGGCGCAGCTGATGGGCCCCAATGCCAAGGAGCTCTTTCGGCTGGTGGAGGA
  CTTTGTGGATGTCATCGGCTTCCGCATGAAGGATTTGAGGGATGCCTACCAGGTGACAGACAATCTGGTG
  CTCAGCATCCACAAGCTTCCGGCCAGTGGGGCCACCGACATCAGCTTCCCTATGAAGGGCTGGCGTGCCA
  CCGGAGACTGGGCCAAGGTGCCAGAGGACAGGGTCACCGTGTCCAAGAGTGTGTTTTCCACAGGGCTGGC
  AGAAGCTGACGATTCATCTGTGTTCGTGGTTGGTACTGTGCTCTACCGAAACTTGGGCAGCTTCCTGGCC
  CTGCAGAGGAACACAACTGTCCTCAACTCTAAGGTCATCTCCGTGACTGTGAAGCCCCCGCCTCGATCGC
  TGCTCACACCCTTGGAGATCGAGTTTGCCCACATGTACAACGGCACTACCAACCAGACCTGTATCCTGTG
  GGATGAGACAGATGGACCCTCCTCCTCCGCCCCCCCGCAGCTCGGGCCCTGGTCGTGGCGCGGCTGCCGC
  ACGGTGCCCCTCGATGCCCTCCGGACGCGCTGCCTGTGTGACCGGCTCTCCACCTTCGCCATCTTAGCCC
  AGCTCAGCGCCGACGCGACCATGGATAAGGTGACCGTGCCCTCTGTGACGCTCATCGTGGGCTGTGGCGT
  GTCTTCCCTCACCCTGCTCATGCTGGTCATCATCTACGTGTCTGTGTGGAGGTACATTCGCTCAGAGCGG
  TCCGTTATCCTCATCAATTTCTGCCTGTCCATCATCTCCTCTAATGCTCTCATCCTTATCGGGCAGACCC
  AGACCCGCAACAAGGTTGTGTGCACGCTGGTGGCTGCCTTCTTGCACTTCTTCTTCCTGTCCTCATTTTG
  CTGGGTGCTCACCGAGGCCTGGCAATCCTACATGGCCGTCACCGGCCGCCTCCGGAGCCGGCTCGTCCGC
  AAACGCTTTCTCTGCCTGGGCTGGGGGCTCCCTGCACTGGTGGTGGCCATTTCTGTGGGATTCACCAAGG
  CCAAGGGCTACAGCACCATGAACTATTGCTGGCTCTCCCTGGAGGGGGGACTTCTGTATGCCTTCGTGGG
  ACCGGCAGCTGCAGTTGTGCTGGTGAACATGGTGATCGGGATCCTGGTGTTCAACAAGCTCGTGTCCAAG
  GACGGCATCACGGACAAGAAGCTGAAGGAGCGGGCAGGGGCCTCCCTGTGGAGCTCCTGCGTGGTGCTGC
  CGCTGCTGGCGCTGACCTGGATGTCTGCTGTGCTTGCTGTCACCGACCGCCGCTCCGCCCTCTTCCAGAT
  CCTCTTCGCTGTCTTTGACTCACTGGAGGGCTTCGTCATCGTGATGGTGCACTGCATTCTGCGCAGAGAG
  GTCCAGGATGCTGTGAAGTGCCGTGTGGTAGACCGACAAGAGGAGGGCAACGGGGACTCAGGGGGCTCCT
  TCCAGAACGGCCATGCCCAGCTCATGACCGACTTTGAGAAGGATGTGGATCTGGCCTGTAGATCAGTGCT
  GAACAAAGACATTGCAGCCTGCCGCACAGCAACTATCACAGGTACCTTCAAGCGACCATCACTGCCTGAA
  GAGGAGAAGATGAAGCTGGCCAAGGGCCCACCCCCCACCTTCAACAGCCTGCCAGCTAATGTGTCCAAGC
  TGCACCTGCACGGTTCACCCCGCTATCCTGGTGGGCCACTGCCTGACTTCCCTAATCACTCACTCACCCT
  CAAAAAGGACAAGGCCCCCAAGTCCTCTTTTATTGGCGATGGGGACATCTTTAAGAAACTGGACTCCGAG
  CTGAGCCGAGCCCAGGAGAAGGCTCTGGACACGAGCTACGTGATCCTGCCCACGGCCACGGCCACACTCC
  GGCCCAAACCCAAGGAGGAACCCAAATACAGCATCAACATTGACCAGATGCCCCAAACCCGCCTCATCCA
  CCTTAGCATGGCACCTGATGCCAGCTTCCCTACCCGAAGCCCACCTGCCCGTGAGCCCCCAGGTGGTGCA
  CCCCCTGAGGTGCCCCCTGTCCAGCCCCCACCACCGCCACCTCCACCACCCCCTCCACCCCAACAGCCCA
  TACCCCCACCACCCACCCTGGAGCCTGCACCTCCCAGCCTGGGGGACACGGGGGAGCCTGCGGCCCACCC
  GGGACCCAGTTCAGGTGCTGGGGCCAAGAATGAGAACGTGGCCACCTTGTCAGTGAGCTCTCTGGAGCGG
  CGGAAATCACGGTATGCAGAACTGGACTTTGAGAAGATCATGCACACACGGAAGCGACACCAAGACATGT
  TCCAGGACCTGAACCGGAAGCTGCAGCATGCGGCTGAGAAGGAGAAGGAGGTGCCAGGCGCAGACAGCAA
  GCCAGAGAAGCAGCAGACTCCCAACAAGAGGGCCTGGGAGAGCCTCCGCAAGCCCCACGGGACGCCTGCC
  TGGGTAAAAAAGGAGCTGGAGCCACTGCCCCCGTCTCCACTGGAGCTGCGGAGCGTAGAGTGGGAGAAGG
  CGGGTGCCACCATCCCACTGGTTGGCCAGGACATCATTGACCTCCAGACCGAGGTCTGA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_174991
• Insert Size: 4749 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_174991.3, NP_778156.2
• RefSeq Size: 6227 bp
• RefSeq ORF: 4749 bp
• Locus ID: 107831
• UniProt ID: Q3UHD1
• Cytogenetics: 15 D3
• Gene Summary: Phosphatidylserine receptor which enhances the engulfment of apoptotic cells (PubMed:17960134). Also mediates the binding and engulfment of Gram-negative bacteria (PubMed:21245295, PubMed:26838550, PubMed:26838550). Stimulates production of reactive oxygen species by macrophages in response to Gram-negative bacteria, resulting in enhanced microbicidal macrophage activity (By similarity). In the gastric mucosa, required for recognition and engulfment of apoptotic gastric epithelial cells (By similarity). Promotes myoblast fusion (PubMed:23615608). Activates the Rho pathway in a G-protein-dependent manner (By similarity). Inhibits MDM2-mediated ubiquitination and degradation of DLG4/PSD95, promoting DLG4 stability and regulating synaptic plasticity (PubMed:25751059). Required for the formation of dendritic spines by ensuring the correct localization of PARD3 and TIAM1 (By similarity). Potent inhibitor of angiogenesis in brain and may play a significant role as a mediator of the p53/TP53 signal in suppression of glioblastoma (By similarity).[UniProtKB/Swiss-Prot Function]
  Transcript Variant: This variant (1) encodes the longer isoform (1).