Ino80 (NM_026574) Mouse Untagged Clone

CAT#: MC224684

Ino80 (untagged) - Mouse INO80 homolog (S. cerevisiae) (Ino80), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Ino80
• Synonyms: 2310079N15Rik; 4632409L19Rik; Inoc1
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC224684 representing NM_026574
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGCCTCGGAGTTGGGTGCCGGGGACGATGGCAGCAGCACTGAGCTGGCAAAGCCCCTTTATCTTCAGT
  ACCTGGAGAGAGCCTTGCGGTTGGACCACTTTCTGCGACAAACATCAGCCATCTTCAACAGGAATATTTC
  TAGTGATGACAGTGAAGATGGACTGGATGACAATAATCCCTTATTGCCTGAGTCTGGGGATCCCTTAATA
  CAAGTAAAAGAAGAGCCTCCAAATTCATTGCTTGGCGAAACCTCTGGAGCAAGCAGTTCTGGGTTGTTGA
  ACCCATATTCACTGAACGGCGTTCTGCAGTCAGAATCAAAATCTGACAAGGGGAATTTATATAACTTCTC
  TAAGTTGAAGAAAAGCAGAAAGTGGCTAAAGAGCATTCTTTTAAGTGATGAGTCCAGTGAGGCAGATTCT
  CAGAGTGAAGACAATGATGATGAAGAAGAAGAACTCAGTCTCAGCAGAGAAGAACTTCACAACATGCTTC
  GATTACACAAATATAAGAAACTTCACCAAAATAAATATAGTAAAGATAAGGAGTTGCAGCAGTACCAGTA
  CTACAGTGCAGGCCTGCTCTCTACATACGACCCTTTCTATGAGCAACAGCGCCACTTGCTTGGACCCAAA
  AAGAAGAAATTCAAGGAAGACAAGAAGCTTAAAGCCAAGTTGAAAAAAGTGAAGAAAAAAAGAAGACGTG
  ATGAAGAGTTTTCCTCTGAAGAATCTCCACGTCACCACCATCACCAGACCAAAGTCTTTGCTAAGTTTTC
  TCATGATGCACCTCCCCCTGGCACCAAGAAGAAACACTTATCCATTGAGCAGCTTAATGCCCGCCGCAGG
  AAAGTGTGGCTGAGCATCGTGAAAAAGGAACTACCAAAGGCCAACAAGCAGAAGTCTTCAGCTCGAAACT
  TATTTCTTACCAATAGCCGAAAGCTTGCCCATCAATGCATGAAGGAGGTGCGTCGAGCTGCTTTGCAAGC
  ACAGAAAAACTGTAAGGAGACTCTGCCTCGAGCCCGGCGCCTAACAAAAGAGATGCTTCTGTACTGGAAG
  AAGTATGAGAAGGTGGAGAAGGAGCACCGCAAGCGAGCAGAGAAGGAAGCTCTGGAGCAGCGCAAGTTGG
  ATGAGGAAATGCGGGAGGCCAAGAGGCAACAACGAAAACTCAACTTCTTAATCACTCAGACAGAATTGTA
  TGCTCATTTTATGAGTCGAAAACGTGATATGGGTCATGATGGAATCCAGGAAGAAATCTTAAGGAAACTA
  GAAGATAGTTCTACCCAGAGACAAATTGACATTGGTGGAGGAGTGGTGGTTAACATCACCCAAGAAGACT
  ATGATAGTAACCATTTTAAAGCCCAGGCCCTGAAGAATGCTGAAAATGCTTATCATATTCACCAAGCTCG
  AACAAGGTCATTTGATGAAGATGCAAAAGAAAGTCGGGCAGCTGCCCTTAGGGCAGCAGACAAGTCTGGC
  TCTGGGTTTGGGGAGAGTTATAGCTTAGCAAATCCATCTATCCGGGCCGGTGAGGATATTCCGCAACCCA
  CTATTTTCAATGGCAAGTTGAAAGGTTACCAGCTGAAAGGCATGAACTGGTTAGCAAATTTATATGAACA
  GGGTATTAATGGAATTCTTGCTGATGAAATGGGTCTTGGTAAAACTGTACAGAGCATTGCCCTCCTGGCC
  CATCTGGCTGAGAGAGAAAACATTTGGGGACCTTTCTTAATAATTTCACCTGCTTCTACACTTAATAATT
  GGCACCAGGAGTTTACAAGATTTGTTCCTAAATTTAAGGTGCTACCATATTGGGGAAATCCTCATGATAG
  AAAAGTTATCCGGAGATTCTGGAGTCAGAAGACCTTATATACTCAGGATGCCCCCTTTCATGTGGTCATC
  ACTAGCTACCAGCTGGTGGTTCAGGATGTCAAGTACTTCCAGCGGGTCAAGTGGCAATACATGGTACTGG
  ATGAAGCTCAGGCACTGAAGAGCAGTTCCAGTGTTCGTTGGAAGATTCTCTTACAATTCCAGTGTCGAAA
  TCGACTTTTGTTAACTGGAACCCCCATTCAGAATACCATGGCAGAGCTCTGGGCTCTGCTACATTTCATT
  ATGCCAACATTATTTGATTCGCATGAAGAATTTAATGAATGGTTTTCCAAAGACATTGAAAGTCATGCTG
  AAAACAAATCTGCTATTGATGAGAATCAACTCTCTCGTTTACACATGATCTTGAAACCATTTATGCTGAG
  AAGAATCAAAAAAGATGTAGAAAATGAATTGTCTGACAAGATTGAGATTCTAACGTACTGCCAATTGACC
  AGTCGACAAAAACTCTTATATCAGGCACTAAAGAATAAAATTTCCATTGAGGACTTACTGCAGTCTTCAA
  TGGGCTCCACACAACAAGCACAGAACACCACCAGCAGCCTCATGAATTTAGTCATGCAATTCAGGAAGGT
  GTGTAATCACCCAGAGTTATTCGAACGGCAAGAAACGTGGTCTCCATTTCATATTTCTCTAAAGCCATAT
  GAAATTTCGAAGTTTATTTATCGTCATGGACAGATCAGGGTCTTCAACCACTCACGAGATAGGTGGTTGA
  AGGTTCTTCTCTCTCCGTTTGCACCAGATTATATCCAGCAGTCTCTCTTCCATAGGAAAGGTATTAATGA
  AGGAAGCTGTTTTTCTTTCCTTCGATTTATTGATGTCTCGCCAGCAGAAATGGCAAACCTCATGCTTCAG
  GGACTTTTGGCCAGGTGGTTAGCTCTTTTCCTATCTCTGAAAGCCTCCTACAGGCTCCACCAGCTGCGCT
  CTTGGGCAGAGCCGGATGGGACAAGCCATCAGAGCTATCTGAGAAACAAGGATTTTCTTCTCGGAGTTGA
  TTTCCCACTTTCCTTCCCTAACCTTTGCAGCTGCCCTTTGTTAAAGTCTCTTGTTTTCAGCAGCCACTGT
  AAAGCAGTGAGTGGCTACTCAGACCATGTTGTCCATCAGCGGAGATCAGCTACCTCCTCACTTCGTTGCT
  GCCTCCTCACTGAGCTGCCGTCTTTTTTGTGTGTGGCCAGTCCACGAGTCACCGCAGTGCCGTTGGATTC
  TTACTGTAATGACAGAAGTGCAGAGTATGAGAGAGGAGTTCTGAAGGAAGGAGGGAGTCTGGCTGCCAAG
  CAGTGTTTGTTGAATGGGGCTCCTGAGCTGGCTACGGATTGGCTGAGTCGCAGATCCCAGTTCTTCCCAG
  AGCCAGCTGGAGGGCTGCTGAGCATTAGACCCCAGAACGGCTGGTCTTTCATCAGAATTCCAGGCAAGGA
  GAGCCTCATCACTGACAGTGGAAAGCTGTATGCCCTTGATGTCCTGTTGACTCGGCTCAAGTCTCAAGGA
  CATAGGGTCCTTATCTACTCTCAGATGACCAGAATGATAGACCTGCTGGAGGAATATATGGTATACAGGA
  AGCATACCTACATGAGGCTGGATGGCTCGTCCAAGATCTCAGAGAGACGGGACATGGTGGCTGATTTTCA
  GACCAGGAACGACATCTTTGTGTTTCTGTTAAGCACGCGAGCTGGAGGACTGGGTATCAATCTCACAGCT
  GCAGACACAGTGATTTTCTACGACAGTGACTGGAACCCCACTGTAGACCAGCAGGCCATGGATAGGGCCC
  ACCGCTTGGGGCAAACAAAACAGGTCACTGTGTACCGGCTTATCTGTAAAGGCACAATTGAGGAGCGTAT
  TCTGCAGAGAGCCAAGGAAAAGAGTGAGATTCAGCGCATGGTGATTTCTGGTGGGAACTTCAAACCAGAT
  ACCTTGAAACCCAAAGAGGTGGTTAGCCTTCTTCTAGATGACGAAGAACTGGAAAAGAAACTGAGACTGC
  GGCAGGAAGAGAAACGGCAGCAGGAGGAAAGCAACCGAGTGAAAGAACGCAAACGCAAGCGGGAGAAGTA
  CGCAGAAAAGAAGAAAAAGGAAGATGAGTTGGATGGGAAGAGGAGGAAAGAGGGTGTGAACCTCGTGATC
  CCGTTTGTTCCCTCTGCTGACAACTCCAACCTCTCCGCTGATGGGGATGATTCCTTCATCAGTGTCGACT
  CAGCCATGCCCAGCCCTTTCAGTGAGATCTCAATCAGCAGTGAACTGCACACTGGCTCTATTCCCCCTGA
  TGAGAGCAGCAGTGACATGTTAGTCATCGTGGATGACCCAGCCTCCTCAGCACCTCAGTCGAGAGCCACC
  AACTCTCCTGCTTCCATAACAGGCTCTGTGTCAGACACTGTGAATGGAATTTCCATTCAGGAAGTGCCAG
  CTGCAGGACGTGGTCACTCAGCTCGAAGCCGAGGCCGCCCCAAGGGTTCAGGAAGCACAGCCAAAGGAGC
  AGGCAAAGGCCGAAGCCGCAAGTCCACTGCAGGCAGTGCTGCTGCGATGGCAGGAGCCAAAGCAGGGGCT
  GCAGCAGCTTCTGCAGCTGCTTATGCTGCATACGGGTACAATGTGTCTAAAGGAATCTCCGCAAGCAGTC
  CTCTGCAGACATCCATTGTCCGACCTGCTGGCCTTGCAGACTTTGGACCTTCAAGCGCCTCTTCTCCCTT
  AAGTTCCCCTCTGAACAAAGGAAATAATATTCCTGGGACTCCTAAAAGCCTCCACATGACCAGCAGCCTA
  GCCTCAGACTCCTTGATCCGGAAACAGGGCAAAGGCACCAACCCCTCTGGAGGACGGTAA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_026574
• Insert Size: 4680 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_026574.3, NP_080850.2
• RefSeq Size: 6296 bp
• RefSeq ORF: 4680 bp
• Locus ID: 68142
• UniProt ID: Q6ZPV2
• Cytogenetics: 2 E5
• Gene Summary: ATPase component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and DNA repair. Binds DNA. As part of the INO80 complex, remodels chromatin by shifting nucleosomes. Regulates transcription upon recruitment by YY1 to YY1-activated genes, where it acts as an essential coactivator. Involved in UV-damage excision DNA repair. The contribution to DNA double-strand break repair appears to be largely indirect through transcriptional regulation. Involved in DNA replication. Required for microtubule assembly during mitosis thereby regulating chromosome segregation cycle.[UniProtKB/Swiss-Prot Function]