Naip1 (NM_008670) Mouse Untagged Clone

CAT#: MC224395

Naip1 (untagged) - Mouse NLR family, apoptosis inhibitory protein 1 (Naip1), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Naip1
• Synonyms: AV364616; Birc1a; D13Lsd1; Naip; Naip-rs1
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC224395 representing NM_008670
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGCTGAGCATGGGGAGTCCTCCGAGGATCGGATTTCTGAGATTGATTATGAATTTCTCCCTGAGCTCT
  CTGCTCTTCTCGGGGTGGATGCAGTTCAGCTGGCAAAGAGCCAAGAAGAAGAAGAGCATAAAGAACGGAT
  GAAAATGAAGAAAGGTTTTAACTCACAGATGCGCAGTGAAGCCAAACGACTAAAGACCTTTGAGACCTAT
  GACACGTTCAGATCATGGACGCCACAGGAGATGGCAGCTGCTGGGTTTTACCACACAGGGGTGAAACTTG
  GGGTTCAGTGCTTTTGCTGTAGCTTGATCCTCTTTGGCAATAGCCTCAGGAAGCTTCCCATAGAGAGACA
  CAAGAAATTACGTCCAGAATGTGAGTTCCTTCAGGGAAAAGATGTTGGTAACATTGGCAAGTATGACATC
  CGGGTGAAGAGTCCAGAGAAGATGCTGAGAGGTGGCAAAGCCAGGTACCATGAAGAGGAGGCCAGACTGG
  AGTCCTTTGAGGACTGGCCATTTTATGCCCATGGGACATCACCACGTGTACTCTCAGCAGCTGGCTTTGT
  CTTTACAGGTAAAAGGGACACTGTGCAGTGTTTTTCCTGTGGCGGAAGCTTGGGCAACTGGGAAGAAGGA
  GATGACCCCTGGAAGGAGCATGCCAAGTGGTTCCCCAAATGTGAATTTCTTCAAAGTAAGAAATCTTCAG
  AGGAAATTGCCCAGTATATCCAAGGCTATGAGGGATTTGTTCATGTAACGGGAGAACATTTTGTGAATTC
  CTGGGTCAGAAGAGAATTACCTATGGTATCAGCTTACTGCAACGACAGCGTCTTCGCTAATGAAGAACTA
  AGGATGGACACGTTTAAGGACTGGCCCCACGAATCACCTGTGGCTGTTGATGCTTTGGTCAGAGCTGGCC
  TTTTCTACACAGGCAAAAAGGGCATTGTCCAGTGTTTTTCCTGTGGAGGATGTATGGAGAAGTGCACAGA
  AGGTGACGACCCAATACAAGAGCACAACAAGTTTTTTCCCAACTGTGTATTTCTCCAAACCCCGAAGTCC
  TCTGCAGAAGTGATTCCAGCCCTTCAGAGCCACTGTGCACTTCCAGAAGCCATGGAAACCACAAGTGAAA
  GCAACCACGATGATCCAGCAGCAGTTCATTCTACAGTGGTGGGCTTGGGTAGGAGTGAAGCCCAGTGGTT
  TCAAGAGGCCAGGAGTCTGAGTGAGCAGCTAAGAGACAACTACACTAAAGCCACTTTTCGCCACATGAAC
  TTGCCAGAAGTGTGCTCCAGCCTTGGCACTGACCACTTGATCGGCTGCGATGTGTCCATCATTTCAAAGC
  ACATCAGCCAGCCTGTGCAAGGGGCCCTGACGATCCCTGAGGTCTTCTCCAATCTCAGCTCTGTCATGTG
  TGTGGAGGGGGAAACTGGCAGTGGAAAGACAACCTTCCTGAAGAGGATAGCTTTTCTCTGGGCATCAGGA
  TGCTGCCCCTTGTTGTACAGGTTCCAGCTGGTCTTCTACCTCTCCCTTAGTTCCATCACACCAGACCAGG
  GACTGGCCAACATCATCTGTGCCCAACTCCTAGGGGCAGGAGGCTGCATTAGTGAAGTGTGTCTGAGCAG
  CATCATCCAGCAGTTACAACACCAGGTGCTGTTCCTGTTGGATGACTACAGTGGGCTGGCCTCACTCCCC
  CAAGCCCTACATACACTGATTACAAAAAACTACTTGTCACGGACCTGCTTATTGATCGCTGTGCATACAA
  ACAGGGTCAGGGGCATCCGCTCATACCTAGATACGAGTCTAGAGATCAAAGAGTTTCCCTTGTCCAATAC
  TGTCTATATATTAAAGAAGTTCTTCTCCCATAATATAAAACGTCTACTAGAGTTTATGGTTTATTTTGGA
  CAGAATGAAGATTTACAGGGAATTCACAAGACCCCCCTCTTCGTGGCAGCAGTATGTACTGACTGGTTTG
  AAAATCCATCTGACCAGCCCTTTCAGGATATGGCACTTTTCAAGTCCTACATGCAATACCTGTCCTTAAA
  GCACAAAGGTGCAGCTAAGCCTCTCCAAGCCACCGTGTCCTCATGTGGGCAGCTGGCCTTGACAGGGCTT
  TTCTCATCATGCTTTGAGTTCAATAGTGATGACCTGGCAGAGGCAGGAGTTGATGAAGATGAAGAGCTCA
  CCACCTGCTTGATGAGCAAATTCACCGCCCAGAGACTGAGGCCAGTCTACCGGTTTTTAGGTCCGCTGTT
  CCAGGAGTTTCTTGCTGCCATGAGACTGACTGAACTTCTGAGTTCAGATAGGCAGGAAGACCAAGATCTG
  GGACTTTATTATTTGAGACAAATTAACTCACCCTTGAAGGCTTTGACCACCTACAACAATTTTTTGAAGT
  ATGTCTTTAGCCATCCGTCATCAAAGGCAGGGCCAACAGTTGTATCTCATTTGCTTCACTTGGTGGATGA
  GACAGAGTTGCTGGAGAATACCTATAAAAATGAGGATTATGTAAATCACCCTCCAGGAACTTCCCGAATA
  ATGAAGGGACTTAAGGAACTGTGGCTGTTATCTCCTGAATATTACTCTTCATTTGTTTCAGAACATTTAT
  TGCGCATTGCTCTAAACTTTGCTTATGAAAGCAACACTGTTGCTGAATGTTCTCCATTTATTTTGCAGTT
  CCTTAGAGGGAGAACACTGGCTTTGAAAGTACTGAATTTACAATACTTTAGGGACCACCCAGAAAGCCTG
  TTACTGGTGAAGAGTTTAGAAGTCTCGATAAATGGAAATAAAGTGCCAAAAGTTGTAGATTATTCAGTCA
  TGGAAAAAAGTTTTGAAACATTACAGCCACCAACTATAGATCAGGACTATGCATCCGCCTTTGAACAAAT
  GAAGGAACATGAAAAAAATTTATCTGAAAATGAAGAGACCATAAAGAGTATTAAGAACATCTTCCCCTTA
  CAGCCACCTAAAATAAGCTCTGGCTATTGGAAACTGTCCCCCAAGCCATGCAAGATCCCTAGGCTGGAAG
  TTGGAGTGACCAACATGGGTCCAGCAGATCAAGCACTGCTCCAGGTCCTCATGGAAGTCTTCTCAGCTTC
  ACAGAGTATTGAGTTCCGTTTATCCGACAGCAGTGGCTTCCTTGAAAGCATCCGCCCAGCTCTGGAGCTG
  AGTAAGGCCTCTGTCACCAAGTGTTCCATGTCCAGGCTGGAGCTCAGCAGAGCAGAACAGGAGCTGCTTC
  TCACCCTGCCTGCCCTGCAGTCTCTCGAGGTCTCAGAGACAAACCAGTTACCAGATCAGCTCTTCCATAA
  CTTGCACAAGTTCCTGGGCCTGAAAGAACTGTGTGTGAGACTAGATGGCAAACCGGATGTGCTCTCAGTC
  CTTCCTGGAGAGTTCCCAAACCTCCTTCACATGGAGAAGTTATCCATCCGAACCTCCATGGAGTCTGACC
  TCTCCAAACTAGTTAAATTGATTCAGAACTCTCCAAATCTCCATGTTTTCCATCTGAAATGTGATTTCCT
  TTCGAATTGTGACTCTCTCATGGCTGTGCTTGCTTCCTGCAAGAAACTCAGAGAGATTGAGTTTTCTGGA
  CGATGCTTTGAAGCCATGCCCTTTGTTAACATTTTGCCAAATTTTATTTCTCTGAAGATATTAAATCTTA
  TAAGCCAACAATTCCCAGATAAGGAAACATCAGAAAAGTTTGCCCAGGCTCTGGGTTCTCTCAGGAACCT
  GGAGGAACTGCTCGTTCCCACTGGAGACGGGATTCACCAAGTGGCCAAATTGATTGTCCGGCAGTGTCTG
  CAGCTTCCGTGTCTCCGAGTTCTTGCCTTTCACTACATCTTGGACAATGACAGTGTGATTGAAATTGCCA
  GGGTGGCAACCAGTGGAGGTTTCCAGAAACTCGAGAAGTTAGATCTTTCCATGAATCACAAGATTACCGA
  GGAAGGATATAGAAATTTCTTTCAAGCCCTGGACAACCTGCCAAACTTGCAGAATCTGAACATCTGCAGA
  CATATCCCAGAATGCATTCAAGTTCAGGCCACCACTGTCAAGGCTCTGGGTCAATGTGTGTCCCGACTGC
  CCAGCCTCACTAGGCTGCACATGCTCAGTTGGCTCCTGGATGAAGAGGACATGAAAGTGATTAATGATGT
  GAAGGAAAGACACCCCCAGTCCAAACGCTTGATTATCTTCTGGAAATGGATAGTCCCGTTCTCTCCTGTT
  GTCCTGGAGTAA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_008670
• Insert Size: 4212 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_008670.2, NP_032696.2
• RefSeq Size: 5361 bp
• RefSeq ORF: 4212 bp
• Locus ID: 17940
• UniProt ID: Q9QWK5
• Cytogenetics: 13 53.18 cM
• Gene Summary: Anti-apoptotic protein which acts by inhibiting the activities of CASP3, CASP7 and CASP9. Can inhibit the autocleavage of pro-CASP9 and cleavage of pro-CASP3 by CASP9. Capable of inhibiting CASP9 autoproteolysis at 'Asp-315' and decreasing the rate of auto proteolysis at 'Asp-330'. Acts as a mediator of neuronal survival in pathological conditions. Prevents motor-neuron apoptosis induced by a variety of signals (By similarity).[UniProtKB/Swiss-Prot Function]