Yeats2 (NM_001033237) Mouse Untagged Clone

CAT#: MC224331

Yeats2 (untagged) - Mouse YEATS domain containing 2 (Yeats2), transcript variant 2, (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Yeats2
• Synonyms: BC042768; mKIAA1197
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC224331 representing NM_001033237
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGAAGAATAAGGAACATGAGATTGATGTCATTGACCAGCGACTGATTGAAGCCAGGAGGATGATGGATA
  AGCTCCGGGCCTGCATTGTAGCAAACTATTATGCCTCCGCTGGTCTCCTGAAGGTTTCTGAGGGATTAAA
  GACATTTGATCCGATGGCTTTTAATCACCCTGCTATCAAGAAATTTTTGGAATCACCTTCTAGGTCATCA
  TCTCCTACCAATCAGAGATCAGAAACACCATCTGCCAATCACTCTGAAAGTGACTCTTTATCTCAGCACA
  ATGACTTCCTGTCTGACAAAGACAATAACAGCAACGTGGATGTGGAGGAAAGACCCCCAAGCACCGGGGA
  ACAGCGACCGAGCCGAAAGGCAGGAAGGGACACGTCTAGTATCAGTGGCTCCCACAAACGGGAACTACGG
  AATGCTGACCTCACAGGAGATGAGACTTCACGACTGTTTGTCAAGAAAACGATAGTAGTCGGCAACGTGT
  CCAAGTACATACCTCCAGATAAGCGGGAAGAAAATGACCAGTCAACCCATAAGTGGATGGTATATGTCCG
  AGGGTCGCGTAGAGAGCCCAGCATTAATCACTTTGTCAAGAAAGTTTGGTTTTTCCTTCATCCTAGCTAT
  AAACCAAACGATCTTGTGGAAGTTAGAGAGCCCCCCTTTCATCTGACTAGAAGAGGCTGGGGTGAGTTTC
  CTGTCAGAGTGCAAGTTCACTTTAAGGACAGCCAGAACAAGCGGATAGATATCATACACAACCTGAAGCT
  GGATAGAACCTACACTGGCCTACAGACCCTGGGTGCAGAGACGGTGGTGGACGTCGAGCTTCATCGGCAC
  TCGCTTGGTGAAGACTCCGTTTATCCTCAGTCGTCGGAATCAGACGTATGTGATGCCCCGCCTCCAACCC
  TGACGCTTCCAGCCGCCGTGAAAGCCTCAGCAGTGGCACAGTCCCCTGAGCCGGCAGCTGCTGCCCCTGT
  GGGGGAAGGATTCCCAGAGACCACTGAAGCTGAGAGACACAGTACATTTTATTCTTTACCATCTTCGTTG
  GAAAGAACACCCACTAAAGTGACAACAGCACAGAAGGTCACCTTCAGTTCACATGGGAATTCTGCCTTCC
  AGCCTATCGCATCAAGCTGCAAAATTGTGCCACAAAGTCAGGTGCCTAATCCCGAGTCACCTGGCAAGTC
  CTTTCAGCCAATCACCATGAGCTGTAAGATTGTCTCAGGTTCTCCAATATCAACTCCAAGCCCATCACCA
  TTACCTCGCACACCAACTTCCACTCCAGTTCATTTGAAGCAAGGCACTGCCAGTTCTGGTGTCAGCAACC
  CTCATGTTATTGTGGATAAGCCTGGGCAGGTCATTGGAGCCTCCACTCCAAGTACAGGAAGTCCTACAAG
  CAAGCTCCCAGTGGCCTCTCAGGCTTCCCAAGGAACAGGGTCCCCTATTCCTAAGATTCATGGAAGTAGT
  TTTTTGACATCTACTGTGAAGCAGGAGGAGTCTTTATTCGCATCTATGCCACCTCTTTGCCCAATTGGTA
  GTCACCCTAAAGTGCAGAGCCCCAAAGCTGTGACTGGAGGACTTGGGGCTTTCACAAAGGTGATCATCAA
  ACAGGAACCTGGAGAAGCTCCTCATGTGTCCACAACAGGAGCTGCGAGCCAGTCAGCATTCCCTCAGTAT
  GTGACCGTGAAAGGGGGTCACATGATAGCTGTGTCCCCTCAAAAGCAGGTCATAAGTGCTGGAGAAGGGA
  CCACTCAGTCACCAAAGATTGCACCCTCCAAGGTTGTTGGTGTGCCTGTTGGCTCTGCCTTACCTTCCAC
  AGTGAAGCAGGCTGTAGCAATCAGTAGTGGCCAAATCCTTGTCGCCAAGGCCAGCTCTTCTGTCACCAAA
  GCTGTTGGTCCAAAACAAGTTGTGACCCAAGGAGTTGCCAAAGCAATCGTGAGTGGAGGTGGAGGGACCA
  TTGTCGCTCAGCCAGTGCAGACCTTAACCAAGACTCAGGTCACAGCTGCTGGGCCGCAGAAGAGTGGCTC
  CCAGGGCTCAGTAATGGCCACCTTGCAACTACCAGCCACTAATTTGGCCAACCTGGCGAACTTGCCTCCG
  GGCACTAAACTGTACCTTACCACGAACAGCAAGAACCCCTCAGGAAAAGGGAAGCTGCTGCTGATTCCTC
  AAGGAGCCATCCTGCGAGCTACCAACAATGCCAACCTGCAGTCTGGCTCGGCTGCTGCTGGTGGCAGTGG
  CAGCAGTGGTGCAGGGGGAGGCAGTGGAGGTGGCGGTGGCAGCGGAGCAGGAGGAACCCCAAGCACCTCT
  GGCCCAGGAGGGGGCCCCCAGCACCTGACTTACACATCCTACATCCTCAAGCAAACCCCCCAGGGTACAT
  TTTTAGTTGGCCAACCATCACCCCAAACACCTGGAAAACAACTGACTACTGCATCGGTGGTTCAAGGAAC
  ACTGGGAGTCAGTTCATCATCTGCACAGGGACAACAGACACTGAAAGTCATCTCTGGACAGAAAACCACT
  TTGTTTACACAGGCAGCCACTGCTGGGCAGGCATCGCTGCTGAAGTTACCAGACAACACCCTGAAGTCAG
  TGCCAGCAGCTCCACAGCTCGCCAAGCCTGGGACCACGATGCTTCGAGTGGCAGGGGGGGTGATCACAGC
  TGCTCCCTCCCCTGCAGTGGCCTTCTCAGCAAATGGTGCTGTACACCAGTCTGAAGGATCAACCCCTGTG
  TCATCCTCTGTTGGTTCTATAATCAAAACTCCTGGTCAGCCACAAGTGTGTGTAAGCCAGGCCACCATGG
  CAACCTGCAAGGGCCCCGCTGCTGTTGCCGGCACTGCCGCGTCCCTGGTATCTGCACCAAGCTCCATCTC
  TGGGAAAGCCACAGTGTCAGGGTTGCTAAAAGTTCATTCCGCTCAGTCCAGTCCCCAGCAGGCTGTCCTG
  ACAATTCCCAGTCAACTCAAGCCACTAAGCATCAATACCTCTGGTGGCGTGCAGACTGTCTTGATGCCTG
  TGAATAAAGTGGTTCAGTCGTTTTCTACCAGCAAATTACCTACTACTGTCCTGCCCATAAGTGTTCCAAA
  TCAAGCTGCCCCCAGCTCTGCTCCAGTAGCAATTGCCAAAGTGAAGACTGAACCAGAAACTCCTGGGCCA
  AACTGCATCTCACAGGAGAACCAGGTAGCAGTGAAAACAGAAGAGAGCTCTGAGCTAAGCAACTACGTCA
  TTAAGGTAGACCATTTGGAGACCATCCAGCAGCTCCTGACAGCAGTAGTGAAGAAGATCCCATTAATTAC
  TGCAAAAGGTGATGATGCCAGCTGTTTTTCTGCGAAGTCCTTGGAGCAGTATTACGGCTGGAACATTGGG
  AAGAGGAGAGCTGCTGAGTGGCAAAGAGCAATGACAGTACGAAAAGTGTTACAAGAAATCCTGGAGAAGA
  ATCCAAGATTCCACCACTTGACTCCCCTCAAGACCAAGCACATTGCTCACTGGTGCCGCTGCCACGGTTA
  CACCCCACCAGACCCCGAGAGCCTGCGACATGATGGAGACTCCATTGAGGATGTGCTGACCCAGATTGAC
  AGTGAACCAGAGTGCCTGTCATCCTTCTCCACTGCTGATGACCTCTGCCGGAAGCTGGAGGATCTGCAGC
  AGTTCCAGAAAAGGGAGCCTGAGAACGAGGAAGAAGTGGATATCCTCAGCCTGTCAGAGCCACTGAAGAC
  AAACATTAAAAAGGAGCAGGAAGAAAAGCAGGAAGAAATGAGATTCTACCTTCCACCAACCCCAGGCTCT
  GGATTTGTTGGTGACATTACACAGAAGATTGGAATCACCCTGCAGCCTGTGGCGCTGCACAGGAACATGT
  ATGCCTCAGTGGTAGAGGACATGATCTTAAAGGCCACGGAACAGCTGGTGAGTGACATCCTGAGACAGGC
  ACTGGCAGTTGGATACCAGACAGCATCTCCCAACAGGATTCCCAAAGAAATTACAGTGAGTAATATTCAT
  CAGGCCATTTGCAACATTCCTTTTCTGGATTTTCTTACAAACAAACACATGGGGAGACTGAATGAGGATC
  AGTGA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_001033237
• Insert Size: 4065 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001033237.2, NP_001028409.2
• RefSeq Size: 6024 bp
• RefSeq ORF: 4065 bp
• Locus ID: 208146
• UniProt ID: Q3TUF7
• Cytogenetics: 16 A3
• Gene Summary: Chromatin reader component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. YEATS2 specifically recognizes and binds histone H3 crotonylated at 'Lys-27' (H3K27cr). Crotonylation marks active promoters and enhancers and confers resistance to transcriptional repressors.[UniProtKB/Swiss-Prot Function]
  Transcript Variant: This variant (2) is missing an exon found in transcript variant 1, which results in translation initiation from an in-frame downstream AUG, and an isoform (2) with a shorter N-terminus compared to isoform 1.