Cdhr2 (NM_001033364) Mouse Untagged Clone

CAT#: MC224208

Cdhr2 (untagged) - Mouse cadherin-related family member 2 (Cdhr2), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Cdhr2
• Synonyms: Gm624; PC-LKC; Pcdh24
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC224208 representing NM_001033364
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGCCTGGCTGTGGCTGCTTTGTGCACTGCTTCCTGCCTTCATGGTATCTGTGACAGCCAACTCGCCAC
  CATCATTTGGGGTCAATATGACATTAGTAACCCTGCCAGAGGACTTACCAGTGGGTGCCGTGGCCTTCTG
  GTTGGTGGCTACAGACAGTGATAATGACCACCTGACCTATGGAATCAGTGGCCCAAACGCCAGCTACTTC
  TCCGTCAACGCGAACACTGGGGAAGTGAAGCTTGCCAGCCCTTTGGACTTTGAGACAGTTCCTTTCTTCA
  AGATCACCATCTCCACAAGTGATGGTCTCAACATCAGAACAGCCGAGATGCAAGTGATTGTGGAAGACAG
  AAATGATAACATACCTGTTTTCCTGAACACTGAATTCTCCACCAGCATCAATGAGACCCTGCCAGTCGGT
  TCTGTGGTGTTTTCTGTGCTGGCAGAGGACAAGGACACAGGGACAGCCGGTTTGGTGCAATATTTCATAG
  AGAAGGTCATCCCCAGCACCGCCAACAGCAATAATCTCTTCCGCATCCTGGAAAATGGCTCCATTGTACT
  GAATGACACGCTCAGTTACAACAACAAGAGTGCCTTCTACCAGCTGGAGCTGAAGGCCTGTGACTCAGGG
  GGAATATTGGATAACAAGCCAAAAACCCAATGCTCCCAGCCGGTCTTCGTATCCATCTCAGTGATTGATG
  AGCCAGACCTGGACCCTCGGTTTATCAGGGAGTTCTACTCAGCCTCTGTGGCTGAGGATGCCACCTTGGG
  GACGTCCGTGCTGACCGTGGAGGCTGTGGACAGTGACAAAGGCATCAATGACATTGTGACCTACAGTGTC
  TCCAACTCCACGAGGCCTGGGTGGTTCGACATCAGGGAAGATGGGGTCATCTTCGTCAATGGCTCCCTGG
  ACAGAGAGCAGCTGCTTCTGGAAAACGAAGAAGTGCAGATACAGGTCACGGCCACCGAGAAGAATCTGAA
  CATCTACGGGCAAGAGGCCAAGGCAAGCATGTGGGTCACAATAAGGGTGACAGATGTCAACGACCACAAG
  CCGGAATTTTACAACTGCAGCCTCCCTGGCTGCTCCTTTAGCCCCCAGGAGGCCCAAGTCAACTTCATAG
  GCTACGTGGACGAGCATGCCTCTGCCCGAATCTCCATCGATGGTCTGACCATGGTGGCCTATGATCCAGA
  CCAGGGCGACAATGGTACCTTCCTGCTGTCCCTGAATGGCCAGGATGCTGAAGCCTTCAATGTGTCCCCA
  GAGCGAGCAGCAGGGTCTGTCAGTGTGCAGGTGGTGGTGAGAAACTCAGAGATGGTGGACTATGAGAAGG
  AGACAGTGATGGTTGTGGAGGTTGTGGCCACTGACTCAGTCAGCAACAACTACTCTGTTGCCACGGTGAC
  CATCCACCTTAGAAACATCAATGACCACAGGCCTGTGTTCTCTCAGAGCCTGTATGAACTCACTGTGCCA
  GAGCACTGTCCAACAGGTTATCTGGTCACTGACAAAATCCAGGCTACAGACCTGGATGGGGATGAATGGG
  GTCCTATCACCTACAGTCTGCTTCCAGGAAATGGAGCTGACCTGTTTGAGGTGGAGCCAAACTCAGGGAA
  TCTGACGGTGAAAAATGGCACGCTGCTGGACCGAGAGAAGCAGGCTGTGTACTACCTCACGCTGCAGGCC
  ACTGACGGTGGCAACCAGTCGACCACCACCGCCCTGGAGATCACTCTGCTGGATATCAATGACAACCCGC
  CTGTGGTCCGAGGCTCCTATAACGTCTTCGTGCCGGAGGAGAATGGCAATGTCTCTGTGACCATCCAGGC
  CTATGATGATGACCAGCCAGACACTAACAACAGCCTCCTGGTCTTCAGCCTGCTTCCTGGGCCCTACAGC
  AGCAACTTCTCCTTAGACCCCAACACAGGGCTCCTCAGGAATCTTGGGCCCCTGGACCGAGAGGCCATTG
  ACCCTGCCCTGGAGGGACGCATCGTGCTAACTGTGATTGTGGCTGACTGCGGCGAGCCTTCCCTGAGCAC
  TAATGTCAATGTCACCATCACGGTAGAGGACATCAATGACAACCTGCCTGTCTTCAACCAGTCTTATGAA
  TTCTCTGTGTGGGAGAGAGTTCCAGGAGCATGGGTGGGCACAGTGAAGGCCTGGGATGCTGACCAGACGG
  CAGCCAACAACCGCATCAGCTTCAGCTTGTCTGGGACTGGCGCCAACAATTTTATCCTCCAAGGCAACGT
  GCTGGAACAAGGGTGGGCAGAGGGTAGCCTCTGGCTGCTCCCGGATGTGAGACTGGATTACGAGACACAG
  AAGTTCTTCCACCTGACAGTGAGTGCTGAGAACCCAGGCCCCCAGGGCCTCGATTCTACAGCCAATGTCA
  CCGTCACGGTGATGGATGTGAATGATGAGCCGCCCACCCTGGATGCAGCCTCACTCCAGGCCATCTCTGT
  GACTGAGAATGGCTCTGAGCATGGCCAGGTGACTCGGGTGATAGCCCAGGATGTGGATACTGCTGCGTTG
  CTGAGGATAGAGCTGGTGGACGTCATCTGCACCAAGGCTGGGGTTGACGTGGGCAGCGTGTGTCACGGCT
  GGTTCTCTGTGGATGGCAACGGCTCTGTGTACATCAATCAGAGTGAGGCCATCGACTATGAGGCTTGTCA
  CCTGGTCACGCTGGTCGTGCGGGCGTATGACCTCAACACGGATCCGGGCTTTGATGCTTACAGCAGCAAT
  GGAAGCCTTCTCATCAACATCAAGGACAAGAATGACAATGCCCCCTATTTTCTGCCTAACAACCAGACCT
  TCGTGATCATCCCAGAGCTTGTGTTGCCCAACCAGCAGGTGGCTTCTGTCCAGGCCAGAGATGAGGACTC
  AGAAGACAATGGGATCATCATGTTCTCCATCCTGAAAGCAGAATTTGTCCGCAAAGATGGAACTTCCAAC
  CCTGTCCAGGTCTTCCGGATTACCAGATCAGTGGAAGCTGGCCTGTTCACTGGCAGCATCGAGTTGGTGA
  CCAACCTAGATTCTACTATCCAAGGCACATACCAGGTGACAGTTCAGGCCCAAGATCAGCCCACATTGGG
  TCCTGCCCTAGAGACACAGACCACTCTGAATCTCTTCACTGTGGACCAGAGTTACCGTGTGAGGCTGCAG
  TTCTCCACCAGCAAGGAGGATGTTGGTGCCAATATGGAGGAGATCAAGGAGGCTCTTATCCAGGCGACCA
  GAACCTCTGTCTACGTTGTGACCATCCAGAACATAGACTCTACGGCTCGGGCCCGAGCCAGCTCCTACAT
  GGACGCCTACTTTGTCTTTTCCAATGGGACAGCCCTGACACTCACTGAGCTGAATATGATGATCCGGAAA
  GACCAGGATGCACTGAGGCAGCTGCTGCAACTGGGGCTGGTGGTGGTGAGCTCCCAGGAGAGCCAGGAGC
  CCGATCAGCAGAAACTGCTCACCAGTGTCATCATAGGACTGGTGGTGTCTTTGGTGCTGGTCCTTGTGAT
  TTTGATTACGGCCCTTGTGTGTTTGCGGAAGAGCTATCACCGGAAGCTTCGAGCTATGAAGGCTGGCAAG
  GAGGCCCGAAAGACACCAATAGAGACGACAGCTCCAACTGCTGCTATCCCAGGGACTAACATGTACAATA
  CTGATCGGGCCAACCCCGTGCTGGACCTCCCCACCAAGGATCTGGGCTTGGAGTGCCACTCCTCCAGTGA
  CTTGGACTATGACAGCCTCAATTCCCTAGATGAGAACTCTGTGGACTTGGACATGGACAGTAAGGAATTC
  AAGAGGAAGGATCTTCCAGGAGACCCTCCTGAGCCTGACCCTGAGCCCCTGACTGCAGTGCTCTCAGGAA
  GGTCGGCAGGTGCGAGCGAACAGCAGAAAAAGAATCTGTCCTTCACCAACCCTGGCCTGGACACCACAGA
  TCTGTGA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_001033364
• Insert Size: 3927 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001033364.3, NP_001028536.2
• RefSeq Size: 4131 bp
• RefSeq ORF: 3927 bp
• Locus ID: 268663
• UniProt ID: E9Q7P9
• Cytogenetics: 13 B1
• Gene Summary: Intermicrovillar adhesion molecule that forms, via its extracellular domain, calcium-dependent heterophilic complexes with CDHR5 on adjacent microvilli. Thereby, controls the packing of microvilli at the apical membrane of epithelial cells. Through its cytoplasmic domain, interacts with microvillus cytoplasmic proteins to form the intermicrovillar adhesion complex/IMAC. This complex plays a central role in microvilli and epithelial brush border differentiation. May also play a role in cell-cell adhesion and contact inhibition in epithelial cells.[UniProtKB/Swiss-Prot Function]