Magi2 (NM_001170746) Mouse Untagged Clone

CAT#: MC224130

Magi2 (untagged) - Mouse membrane associated guanylate kinase, WW and PDZ domain containing 2 (Magi2), transcript variant 1, (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Magi2
• Synonyms: Acvri1; Acvrinp1; Acvrip1; AIP-1; Magi-2; mKIAA0705; S-SCAM
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC224130 representing NM_001170746
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGTCCAAAAGCTTGAAAAAGAAAAGCCACTGGACTAGCAAAGTCCACGAGAGTGTCATTGGCAGGAACC
  CGGAGGGCCAGCTGGGCTTTGAACTGAAGGGGGGCGCGGAAAACGGACAGTTCCCCTACCTGGGGGAGGT
  GAAGCCGGGCAAGGTGGCCTATGAAAGCGGCAGCAAGTTGGTGTCCGAGGAGCTGCTGCTGGAGGTGAAC
  GAGACCCCCGTGGCGGGGCTCACCATCAGGGACGTTCTGGCCGTGATCAAACACTGCAAGGACCCCCTCC
  GGCTCAAGTGTGTCAAGCAAGGAGGAATTGTTGATAAAGACCTTCGTCACTACCTCAACCTAAGATTTCA
  GAAGGGTTCTGTTGACCATGAACTACAGCAAATCATCCGTGACAACCTCTACCTCCGCACAGTGCCATGC
  ACCACAAGGCCACATAAGGAGGGTGAGGTCCCTGGAGTGGACTACATTTTCATAACCGTTGAGGAGTTTA
  TGGAATTGGAGAAAAGTGGTGCTCTCCTAGAAAGCGGGACCTATGAAGACAACTACTACGGTACCCCGAA
  GCCTCCAGCTGAACCAGCACCATTATTAAATGTAACAGACCAGATACTTCCGGGAGCTACTCCAAGTGCT
  GAGGGGAAGCGGAAAAGAAATAAGTCAGTGACCAACATGGAGAAAGCAAGTATAGAGCCTCCAGAGGAGG
  AAGAAGAAGAAAGGCCTGTAGTCAATGGAAACGGCGTGGTCATAACCCCAGAATCCAGTGAACATGAAGA
  CAAAAGTGCAGGTGCCTCAGGGGAGACACCCTCCCAGCCTTACCCTGCACCCGTGTACAGCCAGCCCGAA
  GAGCTCAAGGACCAGATGGACGATACAAAGCCAACAAAGCCTGAGGAGAACGAGGACTCTGATCCATTGC
  CTGATAACTGGGAAATGGCCTACACAGAGAAGGGGGAAGTCTACTTCATTGACCATAACACAAAGACAAC
  ATCATGGCTGGATCCGCGACTTGCGAAAAAGGCTAAACCTCCAGAAGAGTGCAAAGAAAATGAGCTTCCA
  TATGGCTGGGAAAAAATCGATGATCCTATATATGGCACTTACTATGTTGACCACATAAATAGAAGAACAC
  AGTTTGAAAACCCTGTCCTGGAAGCAAAAAGGAAGCTACAGCAACATAACATGCCCCACACAGAACTTGG
  AGCAAAGCCCCTGCAGGCCCCAGGTTTCCGAGAAAAGCCACTCTTCACCCGGGATGCATCCCAGTTGAAG
  GGAACGTTCCTCAGCACCACCCTCAAAAAGAGCAACATGGGCTTTGGGTTTACCATCATTGGTGGAGACG
  AGCCGGATGAGTTTCTACAGGTGAAAAGTGTGATCCCGGATGGGCCTGCCGCACAGGATGGGAAAATGGA
  GACAGGTGATGTCATTGTCTATATTAATGAAGTTTGTGTCCTTGGACACACTCATGCAGATGTTGTCAAA
  CTTTTCCAGTCTGTTCCTATTGGTCAGAGTGTCAACTTGGTGTTGTGTCGTGGCTACCCTTTGCCCTTTG
  ACCCTGAAGATCCTGCTAACAGCATGGTGCCACCCCTTGCAATAATGGAGAGGCCACCTCCGGTGATGGT
  CAATGGAAGACATAACTATGAAACATACTTGGAATACATTTCTCGGACCTCACAGTCGGTCCCAGATATT
  ACAGACCGGCCACCTCATTCTTTGCACTCCATGCCAGCTGACGGCCAGCTAGATGGCACGTATCCACCAC
  CCGTCCATGACGACAATGTGTCTATGGCTTCGTCTGGAGCCACTCAAGCTGAACTTATGACCTTAACCAT
  TGTGAAAGGTGCCCAGGGATTTGGCTTTACTATTGCCGACAGTCCCACGGGACAGCGGGTGAAACAAATC
  CTTGACATTCAGGGATGCCCTGGGCTGTGTGAAGGAGACCTCATTGTTGAGATCAACCAACAGAATGTAC
  AGAACCTGAGCCATACAGAAGTAGTGGATATACTTAAGGACTGCCCCGTTGGAAGTGAGACTTCTTTAAT
  CATCCATCGAGGAGGTTTCTTTTCTCCATGGAAAACTCCAAAGCCTATGATGGACCGATGGGAGAACCAA
  GGCAGTCCACAAACAAGTTTATCTGCTCCGGCCGTCCCACAGAACCTGCCCTTCCCACCTGCCCTTCACA
  GGAGCTCCTTTCCTGATTCAACAGAGGCCTTTGACCCACGGAAGCCTGACCCATATGAGCTCTACGAGAA
  ATCGAGAGCCATTTATGAAAGTAGGCAACAAGTGCCACCCAGGACCAGTTTTCGAATGGATTCCTCTGGT
  CCAGATTATAAGGAACTGGATGTTCACCTTCGGAGGATGGAGTCTGGATTTGGCTTTAGAATCCTTGGGG
  GAGATGAACCTGGACAGCCTATTTTGATCGGAGCCGTCATTGCCATGGGCTCAGCTGACAGAGACGGCCG
  TCTACACCCAGGAGATGAGCTTGTCTATGTCGATGGGATCCCAGTGGCTGGCAAGACCCACCGCTATGTC
  ATCGACCTCATGCACCACGCGGCCCGCAATGGGCAGGTTAACCTCACTGTGAGAAGAAAGGTGCTATGTG
  GAGGGGAGCCCTGCCCAGAGAATGGGAGGAGTCCAGGCTCTGTATCAACTCACCACAGCTCTCCGCGCAG
  TGACTATGCCACCTACTCCAACAGCAACCACGCCGCCCCCAGCAGCAATGCCTCACCTCCTGAAGGCTTT
  GCCTCACACAGCTTGCAGACCAGTGATGTGGTCATTCACCGCAAAGAAAACGAAGGGTTTGGCTTCGTCA
  TCATCAGCTCTCTGAACAGGCCTGAGTCTGGAGCCACCATAACTGTGCCCCATAAAATTGGACGAATCAT
  TGATGGGAGCCCTGCAGATCGCTGTGCCAAACTCAAAGTGGGCGACCGTATCTTAGCAGTCAACGGCCAG
  TCTATCATCAACATGCCTCACGCTGACATTGTGAAGCTCATCAAGGACGCCGGTCTCAGTGTCACCCTTC
  GCATCATTCCTCAGGAGGAGCTCAACAGCCCAACATCAGCACCCAGTTCAGAGAAACAGAGCCCCATGGC
  CCAGCAGCACAGCCCTCTGGCCCAGCAGAGTCCTCTGGCCCAGCCAAGCCCCGCCACCCCCAACAGCCCA
  GTCGCACAGCCAGCTCCTCCCCAACCTCTCCAGCTGCAAGGACACGAAAATAGTTACAGGTCAGAAGTTA
  AAGCGAGGCAAGATGTGAAGCCAGACATCCGGCAGCCTCCCTTCACAGACTACAGGCAGCCCCCGCTGGA
  CTACAGGCAGCCCCCGGGAGGAGACTACTCACAGCCCCCACCCTTGGACTACAGGCAGCACTCTCCAGAC
  ACCAGGCAGTACCCTCTGTCAGACTACAGGCAGCCACAGGATTTTGATTATTTCACTGTGGACATGGAGA
  AAGGAGCCAAAGGATTTGGATTCAGCATTCGTGGAGGAAGGGAATACAAGATGGATCTGTATGTGTTGAG
  ATTGGCAGAGGATGGGCCAGCCATAAGGAACGGCAGGATGAGGGTAGGAGATCAGATCATTGAAATAAAT
  GGGGAAAGCACACGAGACATGACCCACGCCAGAGCAATAGAACTCATCAAGTCTGGAGGAAGAAGAGTGC
  GGCTGCTGCTGAAGAGAGGCACGGGGCAGGTCCCGGAGTATGGAATGGTACCTTCCAGCCTCTCCATGTG
  CATGAAAAGTGACAAGCATGGGTCCCCATATTTCTACTTACTGGGCCACCCTAAAGACACGACGAACCCC
  ACGCCTGGAGTGCTGCCGCTGCCGCCGCCCCAGGCCTGCCGGAAGTAG
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_001170746
• Insert Size: 3828 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001170746.1, NP_001164217.1
• RefSeq Size: 6736 bp
• RefSeq ORF: 3828 bp
• Locus ID: 50791
• UniProt ID: Q9WVQ1
• Cytogenetics: 5 A3
• Gene Summary: Seems to act as scaffold molecule at synaptic junctions by assembling neurotransmitter receptors and cell adhesion proteins. Plays a role in nerve growth factor (NGF)-induced recruitment of RAPGEF2 to late endosomes and neurite outgrowth. May play a role in regulating activin-mediated signaling in neuronal cells. Enhances the ability of PTEN to suppress AKT1 activation (By similarity).[UniProtKB/Swiss-Prot Function]
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.