Cyfip2 (NM_133769) Mouse Untagged Clone

CAT#: MC224067

Cyfip2 (untagged) - Mouse cytoplasmic FMR1 interacting protein 2 (Cyfip2), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Cyfip2
• Synonyms: 1500004I01Rik; 6430511D02Rik; AA930218; AU022376; mKIAA1168; Pir121
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC224067 representing NM_133769
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGACCACCCACGTCACTTTGGAAGATGCCCTGTCCAACGTGGACCTGCTGGAGGAACTGCCCCTCCCAG
  ACCAGCAGCCATGTATCGAGCCCCCGCCATCCTCCATCATGTACCAGGCTAACTTTGACACGAACTTCGA
  GGACAGGAATGCATTTGTCACGGGCATTGCAAGGTACATTGAGCAGGCAACGGTCCACTCCAGCATGAAT
  GAAATGCTGGAGGAGGGCCACGACTATGCAGTCATGCTGTACACCTGGCGCAGCTGCTCCCGGGCCATCC
  CGCAGGTGAAGTGCAATGAGCAGCCCAATCGGGTCGAGATCTACGAGAAGACGGTGGAGGTGCTGGAGCC
  AGAGGTCACCAAGCTCATGAAGTTCATGTACTTTCAGCGCAAGGCCATCGAGCGCTTCTGTAGCGAGGTG
  AAGCGGCTGTGTCACGCTGAGCGCAGGAAGGACTTTGTCTCTGAGGCCTACCTGCTGACGCTGGGCAAGT
  TCATCAACATGTTCGCGGTCTTGGACGAGCTAAAGAACATGAAGTGCAGTGTCAAGAATGACCACTCTGC
  CTACAAGAGAGCAGCACAGTTCCTAAGGAAGATGGCGGACCCCCAGTCCATCCAGGAATCTCAGAACCTG
  TCCATGTTCCTGGCCAATCACAACAGGATCACCCAGTGTCTTCACCAGCAACTGGAAGTGATCCCGGGCT
  ATGAGGAGCTGCTGGCAGACATTGTCAACATCTGTGTTGATTACTATGAGAATAAGATGTACCTGACGCC
  CAGTGAAAAGCACATGTTGCTCAAGGTGATGGGCTTTGGTCTCTATCTGATGGACGGAAATGTCAGTAAC
  ATTTACAAACTGGATGCCAAGAAGAGAATCAACCTTAGCAAAATTGATAAGTTTTTTAAGCAGCTGCAGG
  TGGTACCCCTTTTCGGCGACATGCAGATAGAGCTGGCCAGATACATTAAGACCAGTGCTCACTATGAAGA
  GAACAAGTCCAAGTGGACATGCACTCAGAGCAGCATCAGCCCCCAGTACAACATCTGTGAGCAGATGGTT
  CAGATCCGGGATGATCACATCCGCTTCATCTCTGAGCTGGCTCGCTACAGCAACAGCGAGGTGGTGACAG
  GCTCAGGGCTGGACAGCCAGAAGTCGGATGAAGAGTACCGGGAGCTTTTTGACCTGGCCCTGCGAGGCCT
  GCAGCTTCTATCCAAGTGGAGTGCCCATGTCATGGAGGTGTACTCTTGGAAGCTGGTTCACCCCACAGAC
  AAGTTCTGCAACAAGGACTGCCCGGGCACCGCGGAAGAGTACGAGAGAGCCACGCGCTACAATTATACCA
  GCGAGGAGAAGTTTGCCTTTGTGGAGGTGATTGCCATGATCAAGGGTTTGCAGGTGCTCATGGGAAGGAT
  GGAGAGTGTCTTCAACCAGGCCATCCGCAACACTATCTACGCAGCCCTGCAGGATTTCGCCCAGGTGACG
  CTGCGGGAGCCGTTGCGGCAAGCAGTTCGAAAGAAAAAGAATGTCCTTATCAGCGTTCTGCAAGCAATTC
  GAAAGACCATCTGTGACTGGGAGGGAGGCCGAGAGCCCCCCAATGACCCATGCTTAAGAGGGGAGAAGGA
  CCCCAAAGGTGGCTTTGACATCAAGGTGCCCCGCCGTGCTGTGGGTCCATCCAGCACACAGCTGTACATG
  GTGCGCACCATGCTTGAGTCACTCATCGCAGACAAGAGCGGCTCCAAGAAGACGCTCAGAAGCAGCCTGG
  ATGGCCCTATCGTCCTTGCCATAGAGGACTTCCACAAGCAGTCCTTCTTTTTCACACACCTGCTTAACAT
  CAGCGAGGCTCTTCAGCAGTGCTGTGACCTCTCCCAGCTCTGGTTCCGAGAATTCTTCCTGGAGTTGACC
  ATGGGCCGGCGAATCCAGTTCCCGATTGAGATGTCCATGCCCTGGATTCTAACGGACCATATTCTGGAAA
  CCAAAGAACCTTCCATGATGGAGTATGTCCTCTACCCCTTGGATCTGTACAACGACAGCGCCTACTATGC
  CCTCACCAAATTCAAAAAGCAGTTCCTGTATGACGAGATCGAAGCCGAGGTAAACCTGTGTTTTGATCAG
  TTTGTCTACAAGCTGGCTGACCAGATCTTCGCCTACTACAAAGCCATGGCCGGCAGTGTCCTGCTGGATA
  AACGTTTTAGAGCTGAGTGTAAGAACTATGGGGTGATCATACCGTACCCGCCATCCAACCGCTACGAGAC
  ACTGCTGAAGCAGAGACATGTCCAGCTGTTGGGGAGATCAATTGACTTGAACAGACTCATCACCCAGCGG
  ATCTCTGCTGCCATGTACAAGTCCTTGGACCAGGCCATCAGCCGCTTTGAGAGTGAAGACCTGACCTCCA
  TTGTGGAGCTGGAGTGGCTGCTGGAGATTAACCGACTCACACACCGACTCCTCTGTAAGCACATGACGCT
  AGACAGCTTCGATGCCATGTTCCGAGAAGCCAATCATAACGTGTCTGCCCCTTACGGCCGCATCACCCTG
  CATGTCTTCTGGGAGCTGAACTTTGACTTTCTCCCCAACTACTGCTATAATGGATCCACAAACCGTTTTG
  TCCGAACTGCCATCCCTTTCACCCAAGAACCACAACGGGATAAGCCCGCCAATGTCCAGCCTTATTACCT
  CTATGGATCCAAGCCTCTCAACATTGCCTACAGCCACATCTATAGCTCCTACCGGAACTTTGTGGGGCCC
  CCTCACTTCAAGACCATCTGCAGACTGTTGGGCTACCAGGGCATCGCTGTGGTCATGGAGGAACTGCTGA
  AAATCGTCAAGAGCTTGCTCCAAGGCACCATCCTGCAGTACGTGAAGACGCTCATAGAGGTGATGCCGAA
  AATCTGTCGTTTGCCTCGGCACGAGTACGGCTCTCCAGGAATCCTGGAGTTCTTCCACCACCAACTGAAG
  GACATCATCGAGTATGCAGAACTCAAAACAGACGTGTTCCAGAGCCTCCGAGAGGTGGGCAACGCCATCC
  TGTTCTGCCTCCTCATAGAGCAAGCTCTGTCTCAGGAGGAAGTCTGTGATTTGCTCCATGCTGCACCCTT
  CCAAAACATTCTGCCCCGAGTCTACATCAAAGAGGGGGAGCGCCTGGAAGTCCGGATGAAGCGCCTCGAG
  GCCAAGTACGCCCCACTTCACCTGGTTCCCCTGATAGAGCGGCTGGGGACGCCTCAGCAAATCGCCATCG
  CTCGGGAGGGTGACCTGCTGACCAAGGAGCGGCTCTGCTGCGGCCTGTCCATGTTTGAGGTCATCCTGAC
  CCGAATCCGGAGCTACCTGCAGGACCCCATCTGGAGGGGCCCGCCACCCACCAATGGCGTCATGCATGTG
  GATGAGTGTGTGGAGTTTCACCGGCTGTGGAGTGCCATGCAGTTTGTCTACTGTATCCCTGTGGGGACCA
  ACGAGTTCACAGCTGAGCAGTGCTTCGGTGACGGCTTGAACTGGGCCGGCTGCTCCATCATTGTCTTGCT
  GGGCCAGCAGCGGCGCTTTGACCTGTTTGACTTCTGTTATCATCTGCTGAAGGTGCAGAGGCAGGACGGG
  AAGGATGAGATCATTAAGAATGTGCCTCTGAAGAAGATGGCTGACCGCATCAGGAAGTACCAGATCTTGA
  ACAATGAGGTTTTTGCCATCCTGAACAAGTACATGAAGTCTGTAGAGACAGACAGTTCCACCGTAGAGCA
  TGTGCGCTGCTTCCAGCCCCCAATCCACCAGTCATTGGCCACCACCTGCTAG
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_133769
• Insert Size: 3762 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_133769.3, NP_598530.2
• RefSeq Size: 6385 bp
• RefSeq ORF: 3762 bp
• Locus ID: 76884
• UniProt ID: Q5SQX6
• Cytogenetics: 11 B1.1
• Gene Summary: Part of the WAVE1 complex that regulates actin filament reorganization via its interaction with the Arp2/3 complex (By similarity). Involved in T-cell adhesion and p53-dependent induction of apoptosis (By similarity). Does not bind RNA. As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes (PubMed:27605705).[UniProtKB/Swiss-Prot Function]
  Transcript Variant: This variant (1) is the predominant transcript. Variants 1-3 encode the same protein.