Atp8b1 (NM_001001488) Mouse Untagged Clone
$1,743.00
6 Weeks*
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
|---|---|
| Target Symbol | Atp8b1 |
| Synonyms | AI451886; FIC1; Ic |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data | |
| Restriction Sites | SgfI-MluI | |
| ACCN | NM_001001488 |
| Insert Size | 3756 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_001001488.3, NP_001001488.2 |
| RefSeq Size | 6440 bp |
| RefSeq ORF | 3756 bp |
| Locus ID | 54670 |
| UniProt ID | Q148W0 |
| Cytogenetics | 18 E1 |
| Summary | Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. May play a role in asymmetric distribution of phospholipids in the canicular membrane. Plays a role in bile salt homeostasis. In cooperation with ABCB4 may be involved in establishing integrity of the canalicular membrane thus protecting hepatocytes from bile salts. Involved in the microvillus formation in polarized epithelial cells; the function seems to be independent from its flippase activity. Required for the preservation of cochlear hair cells in the inner ear. Required for the preservation of cochlear hair cells in the inner ear. According PubMed:20852622 is proposed to act as cardiolipin transporter during inflammatory injury; the function is questioned by PubMed:21475228.UniProtKB/Swiss-Prot Function |
Reviews
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Resources
"NM_001001488" in other vectors (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| MG224089 | Atp8b1 (tGFP-tagged) - Mouse ATPase class I type 8B member 1 (Atp8b1), (10ug) | 10 ug |
$1,833.00
|
|
| MR224089 | Atp8b1 (Myc-DDK-tagged) - Mouse ATPase, class I, type 8B, member 1 (Atp8b1) | 10 ug |
$1,633.00
|
|
| MR224089L3 | Lenti ORF clone of Atp8b1 (Myc-DDK-tagged) - Mouse ATPase, class I, type 8B, member 1 (Atp8b1) | 10 ug |
$1,933.00
|
|
| MR224089L4 | Lenti ORF clone of Atp8b1 (mGFP-tagged) - Mouse ATPase, class I, type 8B, member 1 (Atp8b1) | 10 ug |
$1,933.00
|
|
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.