Hipk1 (NM_010432) Mouse Untagged Clone
$1,159.00
6 Weeks*
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
|---|---|
| Target Symbol | Hipk1 |
| Synonyms | 1110062K04Rik; Myak |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data | |
| Restriction Sites | SgfI-MluI | |
| ACCN | NM_010432 |
| Insert Size | 3633 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_010432.2, NP_034562.2 |
| RefSeq Size | 8065 bp |
| RefSeq ORF | 3633 bp |
| Locus ID | 15257 |
| UniProt ID | O88904 |
| Cytogenetics | 3 F2.2 |
| Summary | Serine/threonine-protein kinase involved in transcription regulation and TNF-mediated cellular apoptosis. Plays a role as a corepressor for homeodomain transcription factors. Phosphorylates DAXX and MYB. Phosphorylates DAXX in response to stress, and mediates its translocation from the nucleus to the cytoplasm. Inactivates MYB transcription factor activity by phosphorylation. Prevents MAP3K5-JNK activation in the absence of TNF. TNF triggers its translocation to the cytoplasm in response to stress stimuli, thus activating nuclear MAP3K5-JNK by derepression and promoting apoptosis. May be involved in anti-oxidative stress responses. Involved in the regulation of eye size, lens formation and retinal lamination during late embryogenesis. Promotes angiogenesis and to be involved in erythroid differentiation. May be involved in malignant squamous cell tumor formation.UniProtKB/Swiss-Prot Function Transcript Variant: This variant (1) represents the longest transcript ans encodes the longer isoform (1). Both variants 1 and 2 encode the same isoform (1). |
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Resources
"NM_010432" in other vectors (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| MG225509 | Hipk1 (tGFP-tagged) - Mouse homeodomain interacting protein kinase 1 (Hipk1), (10ug) | 10 ug |
$1,254.00
|
|
| MR225509 | Hipk1 (Myc-DDK-tagged) - Mouse homeodomain interacting protein kinase 1 (Hipk1) | 10 ug |
$589.00
$1,054.00
|
|
| MR225509L3 | Lenti ORF clone of Hipk1 (Myc-DDK-tagged) - Mouse homeodomain interacting protein kinase 1 (Hipk1) | 10 ug |
$1,354.00
|
|
| MR225509L4 | Lenti ORF clone of Hipk1 (mGFP-tagged) - Mouse homeodomain interacting protein kinase 1 (Hipk1) | 10 ug |
$1,354.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
