Nek1 (NM_175089) Mouse Untagged Clone
SKU
MC223912
Nek1 (untagged) - Mouse NIMA (never in mitosis gene a)-related expressed kinase 1 (Nek1), (10ug)
$1,153.00
6 Weeks*
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
|---|---|
| Target Symbol | Nek1 |
| Synonyms | D8Ertd790e; kat |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data | |
| Restriction Sites | SgfI-MluI | |
| ACCN | NM_175089 |
| Insert Size | 3612 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_175089.4, NP_780298.2 |
| RefSeq Size | 5419 bp |
| RefSeq ORF | 3612 bp |
| Locus ID | 18004 |
| UniProt ID | P51954 |
| Cytogenetics | 8 30.91 cM |
| Summary | Phosphorylates serines and threonines, but also appears to possess tyrosine kinase activity (PubMed:1382974). Involved in DNA damage checkpoint control and for proper DNA damage repair (PubMed:18843199). In response to injury that includes DNA damage, NEK1 phosphorylates VDAC1 to limit mitochondrial cell death (By similarity). May be implicated in the control of meiosis (PubMed:1382974). Involved in cilium assembly (By similarity).UniProtKB/Swiss-Prot Function Transcript Variant: This variant (3) lacks two alternate in-frame exons, compared to variant 1. The encoded protein (isoform 3) is shorter, compared to isoform 1. |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
"NM_175089" in other vectors (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| MG216282 | Nek1 (tGFP-tagged) - Mouse NIMA (never in mitosis gene a)-related expressed kinase 1 (Nek1), (10ug) | 10 ug |
$1,247.00
|
|
| MR216282 | Nek1 (Myc-DDK-tagged) - Mouse NIMA (never in mitosis gene a)-related expressed kinase 1 (Nek1) | 10 ug |
$589.00
$1,047.00
|
|
| MR216282L3 | Lenti ORF clone of Nek1 (Myc-DDK-tagged) - Mouse NIMA (never in mitosis gene a)-related expressed kinase 1 (Nek1) | 10 ug |
$1,347.00
|
|
| MR216282L4 | Lenti ORF clone of Nek1 (mGFP-tagged) - Mouse NIMA (never in mitosis gene a)-related expressed kinase 1 (Nek1) | 10 ug |
$1,347.00
|
|
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.