Arid5b (NM_023598) Mouse Untagged Clone
$1,138.00
6 Weeks*
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
|---|---|
| Target Symbol | Arid5b |
| Synonyms | 4930580B11; 5430435G07Rik; AI467247; Desrt; Mrf2; Mrf2alpha; Mrf2beta |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data | |
| Restriction Sites | SgfI-NotI | |
| ACCN | NM_023598 |
| Insert Size | 3567 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_023598.2, NP_076087.2 |
| RefSeq Size | 4494 bp |
| RefSeq ORF | 3567 bp |
| Locus ID | 71371 |
| UniProt ID | Q8BM75 |
| Cytogenetics | 10 B5.1- B5.2 |
| Summary | Transcription coactivator that binds to the 5'-AATACT-3' core sequence and plays a key role in adipogenesis and liver development. Acts by forming a complex with phosphorylated PHF2, which mediates demethylation at Lys-337, leading to target the PHF2-ARID5B complex to target promoters, where PHF2 mediates demethylation of dimethylated 'Lys-9' of histone H3 (H3K9me2), followed by transcription activation of target genes. The PHF2-ARID5B complex acts as a coactivator of HNF4A in liver (By similarity). Required for adipogenesis: regulates triglyceride metabolism in adipocytes by regulating expression of adipogenic genes. Overexpression leads to induction of smooth muscle marker genes, suggesting that it may also act as a regulator of smooth muscle cell differentiation and proliferation.UniProtKB/Swiss-Prot Function |
Reviews
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Resources
"NM_023598" in other vectors (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| MG223791 | Arid5b (tGFP-tagged) - Mouse AT rich interactive domain 5B (MRF1-like) (Arid5b), (10ug) | 10 ug |
$1,234.00
|
|
| MR223791 | Arid5b (Myc-DDK-tagged) - Mouse AT rich interactive domain 5B (MRF1-like) (Arid5b) | 10 ug |
$589.00
$1,034.00
|
|
| MR223791L3 | Lenti ORF clone of Arid5b (Myc-DDK-tagged) - Mouse AT rich interactive domain 5B (MRF1-like) (Arid5b) | 10 ug |
$1,334.00
|
|
| MR223791L4 | Lenti ORF clone of Arid5b (mGFP-tagged) - Mouse AT rich interactive domain 5B (MRF1-like) (Arid5b) | 10 ug |
$1,334.00
|
|
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.