Ptpn14 (NM_008976) Mouse Untagged Clone

CAT#: MC223884

Ptpn14 (untagged) - Mouse protein tyrosine phosphatase, non-receptor type 14 (Ptpn14), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Ptpn14
• Synonyms: C130080N23Rik; OTTMUSG00000022087; PTP36
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC223884 representing NM_008976
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGCCTTTCGGCCTGAAGCTCCGCAGGACTCGGCGCTACAACGTCCTGAGCAAGAACTGCTTTGTTACCC
  GGATCCGCCTGCTGGACAGCAATGTCATCGAGTGCACGCTGTCGGTGGAAAGCACGGGGCAAGAGTGCCT
  GGAGGCCGTGGCCCAGAGGCTGGAGCTGAGGGAGACGCACTACTTCGGCCTTTGGTTTCTCAGCAAGAGC
  CAGCAGGCGAGATGGGTAGAGCTGGAGAAGCCACTGAAGAAACATCTGGACAAGTTTGCTAACGAGCCTC
  TGCTTTTCTTCGGAGTCATGTTCTATGTGCCAAATGTGTCACGGCTTCAGCAGGAGGCCACAAGATATCA
  GTATTACCTGCAAGTCAAAAAAGACGTGCTTGAAGGACGGTTGCGGTGCTCCCTGGAACAAGTGATCCGG
  CTGGCTGGCTTAGCTGTGCAAGCTGACTTCGGAGATTATAACCAGTTTGATTCCCAAGAGTTCCTCCGAG
  AGTATGTGCTCTTTCCTATGGATTTGGCCATGGAGGAGGCGGCTCTGGAGGAGCTAACCCAGAAGGTGGC
  CCAGGAACACAAAGCTCATAGCGGGATCCTGCCGGCTGAAGCTGAACTGATGTACATCAACGAGGTAGAG
  CGTTTGGATGGATTTGGACAGGAGATCTTCCCCGTGAAGGACAGTCATGGCAACAGCGTGCACCTCGGCA
  TCTTCTTCATGGGGATTTTTGTGAGGAACAGGGTCGGGAGACAGGCAGTGATATACAGGTGGAATGACAT
  TGGGAGTGTTACTCACAGCAAAGCAGCCATCCTGTTGGAGCTGATTGACAAGGAGGAGACCGCGCTCTTC
  CATACAGATGATATTGAAAATGCCAAGTACATTTCTCGGTTGTTTACCACTCGGCACAAATTTTACAAAC
  AGAACAAGATCTGCACTGAACAGTCAAATTCTCCACCCCCAATTAGACGCCAGCCCACCTGGAGCCGGTC
  CTCACTGCCAAGGCAGCAGCCGTATATCTTGCCTCCCATGCATGTCCAGTGCAGTGAGCACTACTCGGAG
  ACCCATACTTCCCAAGACAGCATTTTCCCCGGGAACGAAGAAGCCTTGTACTGCCGTTCTCACAACAGCC
  TGGACCTTAATTACTTGAACGGCACCGTCACCAATGGCAGCGTGTGCAGCGTTCACAGCGTCAACTCCCT
  CAGCTGCTCTCAGAGCTTCATCCAGGCGTCTCCAGTGTCCTCCAACCTTAGCATCCCTGGGAGTGACATC
  ATGAGGGCCGATTACATCCCCAGCCACCGCCACAGCACCATCATCGTGCCGTCTTACAGGCCGACCCCAG
  ATTACGAGACGGTCATGAGGCAGATGAAGAGGGGTCTGATGCACGCAGACAGCCAGAGCCGGTCTCTGCG
  TAACCTCAATATCATCAACACCCATGCCTATAACCAGCCCGAGGAACTGGTGTACAGCCAGCCGGAGATG
  CGGGAGAGGCATCCCTACACGGTCCCCTATGCACACCAGGGGTGCTACGGTCACAAACTTGTAAGTCCGT
  CTGACCAGATGAACCCCCAAAATTGTGCGATGCCTATCAAGCCAGGGGCCAGTTCCATCTCACACACAGT
  GAGCACTCCAGAACTAGCCAACATGCAGCTCCAAGGAGCACAACACTATAGCACAGCCCACATGCTCAAG
  AACTATCTATTCAGGCCGCCACCCCCTTACCCTCGGCCCCGTCCTGCCACCAGCACCCCAGACCTCGCCA
  GCCACCGCCACAAGTACGTCAGCGGCAGCAGCCCTGATCTGGTAACTCGGAAGGTGCAGCTCTCCGTAAA
  GACCTTCCAGGAGGACAGCTCACCTGTGGTCCATCAGTCTCTGCAGGAGGTGAGCGAACCCCTTACAGCC
  ACCAAGCACCATGGCGGCGGCGGTGGCACGGTGAATAAACGCCACAGCCTGGAGGTGATGAACAGCATGG
  TGAGAGGCATGGAGGCCATGACACTGAAGTCACTCAATATCCCCATGGCTCGCCGCAACACCCTTCGGGA
  GCAGGGCCCTTCCGAGGAGACGGGCGGCCACGAAGTGCACGGTCTCCCCCAGTATCACCACAAGAAGACA
  TTCTCGGATGCCACCATGCTGATCCACAGCAGTGAGAGCGAGGAAGAGGAGGAGACCCTGGAGGCTGCAC
  CTCAGGTTCCTGTGCTTCGAGAGAAAGTAGAATACAGTGCCCAGCTGCAGGCTGCCCTGGCCCGCATCCC
  CAACAGGCCCCCACCTGAGTACCCAGGGCCAAGAAAAAGTGTCAGTAATGGGGCACTGAGACAGGACCAG
  GGAACCCCTCTTCCTGCCATGGCCAGGTGCAGGGTGCTGAGACACGGACCATCCAAGGCCCTCAGTGTCT
  CCCGGGCAGAGCAGCTGGCTGTCAACGGTGCCTCTCTGGGTCCCTCCATCTCTGAGCCTGACCTAACCAG
  CGTGAAGGAGCGGGTCAAGAAAGAGCCTGTGAAGGAAAGGCCGGTGTCAGAGATGTTCTCCCTGGAGGAC
  AGCATTATAGAGAGAGAGATGATGATCAGGAATCTAGAGAAGCAGAAGATGACGGGCCCGCAGGCACAGA
  AGAGACCGCTGATGTTGGCAGCGCTGAATGGGCTCTCGGTGGCCCGAGTGTCGGGGCGGGAAGACGGTCA
  CCATGATGCCACCCGAGTCCCCATAGACGAGAGGCTCAGAGCCCTGAAGAAGAAGCTGGAAGATGGAATG
  GTGTTCACAGAATATGAGCAGATTCCAAACAAAAAGGCCAACGGCGTCTTCAGCACCGCCACTCTGCCTG
  AGAATGCCGAGCGCAGCCGGATCCGAGAAGTTGTCCCATACGAGGAGAATCGAGTGGAGCTCATCCCGAC
  CAAAGAAAACAACACAGGCTATATCAACGCCTCCCACATCAAGGTGGTGGTCGGCGGATCAGAATGGCAC
  TACATCGCCACCCAGGGGCCCTTGCCACATACGTGCCATGACTTCTGGCAGATGGTGTGGGAGCAGGGGG
  TGAATGTGATCGCCATGGTCACTGCAGAGGAGGAGGGTGGACGGACCAAAAGCCATCGATACTGGCCCAA
  ACTGGGGTCCAAGCATAGTTCTGCCACCTACGGCAAGTTCAAGGTCACCACAAAGTTCCGGACAGATTCT
  GGTTGCTATGCAACGACGGGCCTAAAGGTGAAGCACCTGCTGTCCGGGCAGGAGAGGACCGTGTGGCACT
  TGCAGTACACGGACTGGCCCCACCACGGCTGTCCAGAAGACGTCCAAGGATTTTTGTCCTACTTGGAGGA
  AATCCAGTCAGTCCGACGCCACACCAACAGCGTGCTGGAAGGCATCAGGACCAGGCACCCCCCCATCGTG
  GTTCACTGCAGCGCGGGTGTGGGAAGGACTGGTGTGGTTATCCTCTCTGAGCTCATGATCTACTGCCTGG
  AACACAACGAAAAGGTGGAGGTGCCCACGATGCTGCGATTCCTCAGGGAGCAGAGGATGTTCATGATCCA
  GACCATTGCGCAGTACAAGTTCGTCTACCAAGTCCTCGTCCAGTTCCTGCAGAATTCCAGGCTCATTTGA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_008976
• Insert Size: 3570 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_008976.2, NP_033002.2
• RefSeq Size: 10766 bp
• RefSeq ORF: 3570 bp
• Locus ID: 19250
• UniProt ID: Q62130
• Cytogenetics: 1 95.03 cM
• Gene Summary: Protein tyrosine phosphatase which may play a role in the regulation of lymphangiogenesis, cell-cell adhesion, cell-matrix adhesion, cell migration, cell growth and also regulates TGF-beta gene expression, thereby modulating epithelial-mesenchymal transition. Mediates beta-catenin dephosphorylation at adhesion junctions. Acts as a negative regulator of the oncogenic property of YAP, a downstream target of the hippo pathway, in a cell density-dependent manner. May function as a tumor suppressor.[UniProtKB/Swiss-Prot Function]