Itga2 (NM_008396) Mouse Untagged Clone

CAT#: MC223813

Itga2 (untagged) - Mouse integrin alpha 2 (Itga2), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Itga2
• Synonyms: CD49B; DX5
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC223813 representing NM_008396
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGGACCGGGACAGGCAGGGGGCGCGCTCCTGCTGCGGCTGCTAATGCTAGTTCAAGGTATTTTGAATT
  GTCTGGCGTATAATGTTGGCCTCCCAGGAGCGAAAATATTTTCCGGGCCTTCAAGTGAACAGTTTGGGTA
  TTCAGTACAGCAGCTTACGAACCCACAAGGCAACTGGCTACTGGTTGGTTCACCGTGGAGTGGCTTCCCT
  GAGAACCGAATGGGAGATGTGTACAAGTGCCCTGTGGACCTACCCACTGCCACCTGTGAAAAGCTGAATC
  TGCAAAATTCAGCAAGCATCTCAAATGTTACCGAGATAAAGACCAACATGAGCCTGGGATTGACCCTCAC
  CAGGAATCCGGGGACCGGAGGCTTTCTAACCTGTGGTCCTCTCTGGGCACATCAGTGTGGAAATCAGTAT
  TATGCAACTGGGATCTGTTCTGATGTTAGTCCAGACTTTCAGTTCTTGACCAGCTTTTCACCTGCAGTTC
  AGGCTTGCCCTTCCCTCGTGGATGTTGTAGTTGTATGTGATGAATCAAACAGTATTTATCCTTGGGAAGC
  AGTAAAGAACTTTTTGGTAAAGTTTGTGACAGGCCTGGATATAGGACCTAAAAAGACACAGGTGGCGTTA
  ATTCAATATGCCAATGAGCCGAGAATTATATTTAACTTGAACGATTTCGAAACCAAAGAGGATATGGTCC
  AGGCCACATCTGAGACGCGCCAACATGGTGGGGACCTCACAAACACCTTCAGAGCTATCGAATTCGCAAG
  AGACTACGCTTATTCACAGACTTCTGGCGGGCGCCCGGGTGCTACAAAAGTCATGGTAGTTGTGACCGAT
  GGCGAGTCCCATGATGGGTCGAAGCTGAAAACTGTGATCCAGCAATGCAATGATGACGAGATACTGAGGT
  TCGGCATAGCAGTTCTTGGGTATTTAAACAGAAATGCTCTTGATACTAAAAATTTAATCAAAGAAATAAA
  AGCAATTGCTAGTACTCCAACCGAGAGATACTTTTTCAATGTGGCCGACGAAGCGGCTCTTCTGGAGAAG
  GCTGGAACTCTAGGGGAGCAAATATTCAGCATTGAAGGCACTGTTCAAGGAGGAGACAACTTCCAGATGG
  AAATGGCACAAGTTGGATTCAGTGCAGATTACGCTCCTCAAAATGATATTCTGATGTTAGGTGCAGTGGG
  GGCTTTTGACTGGAGTGGAACTCTTGTCCAGGAGACATCTCACAAGCCCGTGATCTTTCCTAAACAAGCC
  TTTGACCAGGTTCTGCAGGATAGAAACCACAGTTCGTTTTTAGGTTACTCTGTGGCTGCAATTTCTACTG
  AAGACGGTGTCCATTTTGTTGCTGGTGCTCCTCGAGCAAATTATACTGGCCAGATAGTGTTGTACAGCGT
  TAACAAGCAAGGCAATGTGACCGTGATTCAGTCTCACAGAGGGGACCAGATTGGCTCCTATTTTGGCAGT
  GTGCTGTGCTCAGTTGATGTAGATAAAGACACCATTACAGACGTGCTCCTGGTAGGTGCTCCTACATACA
  TGAACGACCTCAAGAAAGAAGAGGGAAAAGTCTACCTATTTACCATCACAAAGGGCATCTTGAATCAGCA
  CCAGTTTCTTGAAGGGCCAGAAGGCACTGGAAATGCTCGGTTTGGTTCAGCAATTGCAGCCCTGTCAGAC
  ATCAACATGGATGGCTTTAATGATGTGATTGTCGGTTCACCTGTAGAGAATGAGAACTCTGGAGCTGTGT
  ACATTTACAATGGTCACCAGGGTACCATTCGCACCAAGTACTCCCAGAAAATCCTTGGGTCCAATGGAGC
  CTTTAGGAGACATCTCCAGTTCTTTGGAAGGTCCCTGGATGGCTATGGTGATTTAAATGGGGATTCCATC
  ACTGATGTATCCATTGGTGCTTTGGGGCAAGTGATTCAACTCTGGTCACAAAGCATTGCTGACGTGGCCA
  TAGAAGCTTTGTTCACTCCAGACAAAATCACTTTGCTCAACAAGGATGCTAAGATAACCCTAAAGCTCTG
  CTTCAGAGCAGAGTTTAGACCTGCTGGGCAAAACAATCAAGTAGCCATCCTGTTTAACATGACGCTTGAT
  GCGGACGGACATTCATCCAGGGTAACCTCCAGGGGGGTGTTCAGAGAAAACAGTGAGCGATTCTTGCAGA
  AGAATATGGTGGTAAACGAAGTGCAGAAGTGTTCTGAGCACCACATTAGCATACAGAAGCCCTCTGATGT
  TGTCAACCCTTTGGATCTGCGTGTGGACATCAGTTTGGAAAACCCAGGCACTAGCCCTGCCCTCGAAGCC
  TATTCTGAAACTGTCAAAGTCTTCAGTATCCCTTTCTATAAGGAGTGTGGCAGCGATGGAATTTGCATCT
  CTGACCTGATCCTGGATGTCCAACAGCTGCCAGCCATTCAAACTCAATCCTTTATTGTCAGTAACCAAAA
  CAAGAGGTTAACATTTTCAGTCATCCTGAAAAACAGAGGGGAAAGTGCATACAACACTGTGGTCCTGGCC
  GAGTTTTCTGAGAACTTGTTTTTTGCTTCTTTCTCCATGCCGGTCGATGGAACAGAAGTAACATGTGAGG
  TTGGTTCATCGCAGAAATCTGTTACCTGTGATGTGGGATACCCTGCCTTAAAGAGTGAACAGCAGGTGAC
  TTTTACCATTAACTTCGACTTTAATCTTCAAAACCTCCAGAACCAGGCGGCCATCAATTTCCAAGCCTTC
  AGTGAGAGCCAAGAAACAAACAAAGCAGACAATTCGGTCAGTCTCACGATTCCTCTCCTGTATGATGCCG
  AACTTCACTTAACCCGATCCACCAACATCAACTTCTATGAGATCTCTTCGGATGAGAACGCTCCTTCTGT
  CATCAAGAGTGTCGAAGATATTGGTCCTAAATTCATCTTCTCCCTCAAGGTAACAGCCGGAAGTGCCCCA
  GTGAGCATGGCATTGGTGACTATCCACATTCCTCAGTACACCAAGGAAAAGAACCCACTCCTGTATCTGA
  CTGGGATACAAACAGACCAGGCTGGCGACATCAGCTGCACAGCAGAAATAAATCCACTCAAGCTACCACA
  CACCGCCCCTTCTGTATCTTTCAAGAATGAAAACTTCCGGCATACGAAAGAATTGGACTGCAGAACCACT
  TCCTGCAGTAACATCACCTGCTGGCTGAAAGACCTTCACATGAAAGCAGAGTACTTCATCAATGTGACAA
  CCAGAGTTTGGAACAGGACCTTTGCTGCTTCGACTTTCCAGACTGTGCAGCTGACAGCAGCGGCAGAGAT
  CGATACACATAACCCTCAGCTCTTCGTGATTGAGGAAAATGCTGTCACGATTCCCCTCATGATAATGAAA
  CCCACGGAGAAAGCAGAAGTACCGACAGGGGTTATCATAGGCAGCATAATTGCGGGAATCCTTTTGCTGT
  TGGCTATGACTGCAGGTTTGTGGAAGCTCGGCTTCTTCAAAAGACAATATAAGAAAATGGGCCAAAATCC
  AGATGAGATGGATGAGACCACAGAACTCAACAGCTAA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_008396
• Insert Size: 3537 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_008396.2, NP_032422.2
• RefSeq Size: 4235 bp
• RefSeq ORF: 3537 bp
• Locus ID: 16398
• UniProt ID: Q62469
• Cytogenetics: 13 64.61 cM
• Gene Summary: Integrin alpha-2/beta-1 is a collagen receptor, being responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix. It is also a receptor for laminins, collagen C-propeptides and E-cadherin. Mice homozygous for a null mutation in the alpha-2 die very early in embryogenesis.[UniProtKB/Swiss-Prot Function]