Tnks2 (NM_001163635) Mouse Untagged Clone
SKU
MC223799
Tnks2 (untagged) - Mouse tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 (Tnks2), (10ug)
$1,117.00
8 Weeks*
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
|---|---|
| Target Symbol | Tnks2 |
| Synonyms | 5430432P15Rik; AA517131; AI662480; ARTD6; Tank2; TNKS-2 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data | |
| Restriction Sites | SgfI-MluI | |
| ACCN | NM_001163635 |
| Insert Size | 3501 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_001163635.1, NP_001157107.1 |
| RefSeq Size | 6503 bp |
| RefSeq ORF | 3501 bp |
| Locus ID | 74493 |
| UniProt ID | Q3UES3 |
| Cytogenetics | 19 C2 |
| Summary | Poly-ADP-ribosyltransferase involved in various processes such as Wnt signaling pathway, telomere length and vesicle trafficking. Acts as an activator of the Wnt signaling pathway by mediating poly-ADP-ribosylation of AXIN1 and AXIN2, 2 key components of the beta-catenin destruction complex: poly-ADP-ribosylated target proteins are recognized by RNF146, which mediates their ubiquitination and subsequent degradation. Also mediates poly-ADP-ribosylation of BLZF1 and CASC3, followed by recruitment of RNF146 and subsequent ubiquitination. Mediates poly-ADP-ribosylation of TERF1, thereby contributing to the regulation of telomere length. Stimulates 26S proteasome activity.UniProtKB/Swiss-Prot Function |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
"NM_001163635" in other vectors (2)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| MG215283 | Tnks2 (tGFP-tagged) - Mouse tankyrase TRF1-interacting ankyrin-related ADP-ribose polymerase 2 (Tnks2), (10ug) | 10 ug |
$1,215.00
|
|
| MR215283 | Tnks2 (Myc-DDK-tagged) - Mouse tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 (Tnks2) | 10 ug |
$589.00
$1,015.00
|
|
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.