Fnip1 (NM_173753) Mouse Untagged Clone

CAT#: MC223785

Fnip1 (untagged) - Mouse folliculin interacting protein 1 (Fnip1), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Fnip1
• Synonyms: A730024A03Rik; AI838773; AW557298
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC223785 representing NM_173753
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGCCCCCACCCTGTTCCAGAAGCTCTTCAGCAAGCGGAGCGGATTAGGCGCGCCGGGACGAGACGCCC
  GCGACCCGGACTGCGCGTTCAGTTGGCCCTTGCCAGAATTTGACCCAAGTCAGATTCGACTGATCGTATA
  TCAAGACTGTGAAAGACGAGGGAGAAATGTATTGTTTGACTCCAGTGTTAAGAGAAAAAATGAGGACACA
  TCAGTATCGAAGCTCTGTAATGATGCTCAAGTCAAGGTCTTTGGGAAGTGCTGCCAGCTGAAGCCAGGAG
  GAGATAGTTCTTCCTCTTTGGATAGCTCTATCACTTTATCTTCTGATGGAAAAGACCAGTGTCCCAAATA
  CCAGGGTTCTCGGTGTTCTTCTGATGCCAATATGCTTGGAGAGATGATGTTTGGCTCAGTAGCAATGAGC
  TACAAAGGATCCACCTTAAAAATTCATCAGATCCGCTCGCCTCCACAGCTTATGCTTAGCAAAGTTTTCA
  CCGCACGGACTGGCAGTAGTATCTGTGGGAGTCTCAATACTCTGCAGGACAGTCTTGAATTCATCAATCA
  GGACAGTAATACATTGAAAGCTGATAGCAGCACAGTTAGTAATGGGCTGCTTGGAAATATAGGTCTTTCA
  CAGTTCTGCAGCCCCAGGCGGGCTTTCTCTGAGCAGGGTCCGCTCCGCCTGATCAGGAGTGCCTCTTTCT
  TTGCAGTTCACAGCAACCCAATGGACATGCCAGGAAGAGAACTGAATGAGGACAGAGACAGCGGCATAGC
  ACGTTCTGCATCTCTGAGCAGCTTGTTCATCACCCCATTCCCCTCCCCAAACTCTTCACTTACCCGAAGC
  TGTGCTAGCAGCTACCAGCGACGTTGGCGACGTAGCCAAACAACAAGTTTGGAAAATGGGGTGTTTCCTA
  GATGGTCTGTAGAAGAAAGCTTTAATCTGTCAGATGAAAGTTGTGGCCCTAATCCAGGAATTGTGAGGAA
  AAAGAAGATTGCAATTGGGGTAATCTTTTCATTATCCAAAGATGAAGATGAAAATAACAAATTCAATGAA
  TTCTTTTTTTCACATTTTCCTCTCTTTGAAAGCCACATGAACAAATTAAAAAGTGCAATAGAACAGGCAA
  TGAAAATGAGCCGGAGATCAGCTGATGCCAGCCAGAGAAGTTTGGCATACAATCGAATACTTGATGCCCT
  GACTGAGTTCAGAACAACAATTTGTAATCTTTATACAATGCCAAGAATTGGGGAACCTGTCTGGCTTACA
  ATGATGTCAGGGACTCCAGAGAAGAACCAGCTTTGCCATCGTTTCATGAAGGAATTCACCTTTCTAATGG
  AAAATGCCTCCAAAAATCAATTCTTGCCAGCTCTCATTACTGCAGTTTTGACCAATCATCTTGCCTGGGT
  TCCAACAGTCATGCCAAATGGACAGCCACCTATAAAAATATTTTTAGAAAAACATTCCTCTCAGAGTGTG
  GGCATGTTGGCAAAGACTCATCCATATAACCCTCTTTGGGCACAACTTGGAGATTTGTATGGCGCTATTG
  GATCTCCTGTACGGTTAGCAAGAACTGTAGTCGTTGGCAAACGACAAGACCTGGTCCAGAGACTGCTTTA
  TTTTCTTACTTACTTCATCAGATGCTCTGAACTTCAAGAAACCCATCTTTTAGAAAATGGAGAAGATGAA
  GCCATTGTTATGCCAGGCACAGTGATTACTACCACTTTAGAAAAGGGGGAAATAGAGGAATCAGAGTATG
  TGCTAATCACAATGCATAGAAACAAAAGCAGCTTGCTCTTTAAAGAGTCAGAAGAGACAAGAACTCCCAA
  CTGTAACTGTAAATATTGCAGTCATCCAGTCCTTGGGCAAAATACAGAGAATGTGTCACAACCAGAAAGA
  GAAGATACTCAAGACAACTCTAAGGAATTGCTAGGAATTTCAGATGAATGCCAAAAGATTTCTCCTCCTG
  ACTGCCAAGAAGAAAATGCTGTTGATGTTCAACAGTACAGAGATAAATTAAGAACTTGCCTTGACACCAA
  GTTAGAGACAGTTGTTTGTACAGGATCTGCTCCAGCCGACAAATGTGTGTTGTCAGAGACATGCTTGGAA
  CCAAGAGAAGAATCCTGGCAGAATAAGGAATTGCTGGATTCAGATAATCACACAGGCACAGCAATGAGAC
  CCACAGGAATAGTTGTTGAAAAGAAACCTCCAGATAAGAATGTGCCCAGTGCATTTTCCTGTGAGGTAAC
  TCAGACAAAGGTTACGTTCTTGATTGGAGATTCTATGTCACCTGATTCAGATACTGAACTTCGGAGTCAG
  GCTGTGGTGGATCAGATTAACAGACATCACAGCGAACCACTAAAGGAAGACAGAGGAGTGGCTGATAAGC
  ATCAAGAAAGTAAAATAACTAAGGACCAATCTGAAGACTCTGACACACAGAACATAGTTTCTGGAGAGTC
  CTGTGAGCTTCCTTGTTGGAGTCATTCAGATCCAGAAAGCATGAGCTTGTTTGATGAATATTTTAATGAT
  GATTCAATTGAAACCAGGACTATTGATGATGTTCCAGTTAAAACAAGTACAGATAGTAAAGAGTATTGCT
  GTATGTTGGAGTATCCAAAAAGATTGTATACAAAAACTAACAAACAGAAAAGTGAACTTTGTAAATGTAT
  AGAAACAGTTCATCAAGATTCATGTAATGCCTGCTTTCCTCAGCAGGACCAGAGGAATTCCCTCTCCATT
  CTTGTCCCCCATGGGGATAAAGAGAGTTCAGACAAAAAAAATGCTGTAGGAACTGAATGGGACATTCCAA
  GAAATGAAAGTTCAGATAGTGCCCTTGGAGATAGTGAGAGTGAAGACACAGGCCCGGACATAAGGAGACA
  AGCTGGCGGTTACTGTGGAGGGGACCAGGAAGACTGGACAGAAGAGGATGAGATACCTTTTCCTGGGTCA
  AAATTGATTGAAGTGAGTGCTGTTCAGCCCAACATTGCCAACTTTGGAAGATCTTTGCTGGGTGGCTACT
  GCTCATCTTATGTTCCTGACTTTGTTCTTCAAGGAATTGGAAATGATGAGAGGCTCCGTCAGTGCCTGGT
  ATCAGATTTGTCTCATGCTGTGCAGCATCCAGTGTTAGATGAACCAATAGCAGAAGCTGTCTGTATTATA
  GCTGATATGGATAAATGGACTGTTCAAGTGGCCAGCAGTCAGAGACGAGTAACAGATAATAAATTGGGAA
  AGGAGGTGTTGGTCTCTAGTCTTGTTTCCAACCTGCTTCATTCCACTCTTCAGCTTTATAAACATAATTT
  ATCTCCAAACTTTTGTGTAATGCACCTTGAAGACCGGTTACAGGAGTTATACTTCAAGAGCAAAATGCTG
  TCTGAGTACCTGAGGGGACAGATGCGTGTTCATGTCAAGGAGCTAGGAGTGGTTCTTGGGATTGAATCCA
  GTGACCTTCCTCTTCTGGCTGCGGTAGCAAGCACCCACTCTCCATACGTTGCTCAGATACTCCTTTAA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_173753
• Insert Size: 3498 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_173753.4, NP_776114.2
• RefSeq Size: 6281 bp
• RefSeq ORF: 3498 bp
• Locus ID: 216742
• UniProt ID: Q68FD7
• Cytogenetics: 11 B1.3
• Gene Summary: Acts as a co-chaperone of HSP90AA1. Inhibits the ATPase activity of HSP90AA1 leading to reduction in its chaperone activity. Facilitates the binding of client protein FLCN to HSP90AA1. Competes with the activating co-chaperone AHSA1 for binding to HSP90AA1, thereby providing a reciprocal regulatory mechanism for chaperoning of client proteins. May be involved in energy and/or nutrient sensing through the AMPK and mTOR signaling pathways. May regulate phosphorylation of RPS6KB1.[UniProtKB/Swiss-Prot Function]