Stxbp5l (NM_001114611) Mouse Untagged Clone

CAT#: MC223595

Stxbp5l (untagged) - Mouse syntaxin binding protein 5-like (Stxbp5l), transcript variant s, (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Stxbp5l
• Synonyms: 9430094L02; A830015P08Rik; LLGL4; T2dm1; t2md1; tomosyn-2
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC223595 representing NM_001114611
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGAAGAAGTTTAATTTCCGAAAAGTTTTGGATGGCTTAACTGCCTCTTCCCCTGGCAGTGGTAGCAGCA
  GTGGCAGTAACAGTGGTGGGGCTGGAAGTGGCTCTGTCCATCCAGGAGGGACTGCAGGGCTTCCGAGAGA
  GGAAATTCAGGAAAGCCTGACTTCAGACTATTTCCAGATTTGCAAGACAGTTCGGCATGGGTTTCCTTAT
  CAGCCCACAGCATTGGCCTTTGATCCAGTCCAGAAAATCTTAGCTATTGGAACAAGAACAGGTGCTATAC
  GAATACTTGGGAGGCCTGGTGTTGACTGTTACTGCCAACATGAAAGTGGTGCGGCTGTCTTGCAGCTCCA
  ATTCCTCATCAATGAGGGCGCGTTGGTCAGTGCGAGTTCAGATGACACGCTTCATTTGTGGAATCTGAGA
  CAGAAAAGGCCGGCCATTCTCCATTCTCTTAAATTTAACAGAGAACGAATTACTTACTGTCATCTACCTT
  TCCAGAGTAAATGGCTCTATGTTGGAACAGAAAGAGGAAATACACATATTGTAAATATTGAATCTTTCAT
  TCTTTCTGGATATGTCATCATGTGGAACAAGGCAATTGAACTCTCCACCAAGACTCATCCAGGCCCAGTT
  GTACATTTAAGTGATAGCCCAAGAGATGAAGGAAAACTGTTAATAGGTTACGAGAATGGCACTGTGGTGT
  TCTGGGACTTGAAATCTAAAAGAGCAGAACTGAGAGTTTATTATGATGAGGCTATTCATTCAATTGATTG
  GCATCATGAGGGCAAACAATTCATGTGCAGCCACTCAGATGGTAGCTTGACTTTATGGAACCTGAAAAGC
  CCAAGCCGCCCTTTCCAAACCACAGTCCCACATGGAAAAAGTCAAAGAGAAGGAAGAAAGTCTGAGTCTT
  GTAAACCTATTCTTAAAGTAGAATACAAAACGTGCAGGAACAGTGAACCATTTATAATATTCTCTGGCGG
  GCTGTCATATGACAAAGCTTGCAGAAGACCAAGTTTAACCATCATGCATGGGAAAGCAATTACAGTGCTT
  GAGATGGATCATCCTATTGTTGAGTTTCTAACGTTATGTGAAACGCCCTATCCAAATGAATTTCAAGAAC
  CCTATGCTGTTGCTGTACTTCTAGAGAAAGATCTCATCGTAGTTGACCTGACACAAACCAATTTTCCAAT
  CTTTGAAAATCCATATCCAATGGACATTCATGAGTCACCTGTTACATGCACAGCATATTTTGCCGATTGC
  CCTCCAGATTTGATTCTAGTACTCTATTCTATAGGAGTCAAGCATAAAAAACAAGGATACAGTAATAAGG
  AATGGCCAGTCAGTGGAGGAGCTTGGAACCTCGGAGCACAAACTTATCCAGAAATTATTATTACTGGTCA
  TGCTGATGGAACAATAAAATTTTGGGATGCTTCAGCAATGACACTGCAGATGTTGTACAAGCTAAAAACT
  TCCAAAGTGTTTGAAAAGCAGAAGGCAGGAGAAGGCAAACAGACGTGTGAACTTGTAGAGGAAGATCCCT
  TTGCTGTGCAGATGATCTACTGGTGTCCAGAGAGCAGAATATTTTGTGTCTCTGGAGTCTCTGCATATGT
  CATAATTTATAAATTCAGCAGACATGAAGTCACAACAGAAATAGTGTCACTAGAGGTACGACTTCAGTGT
  GATGTTGAAGACATTATTACTCCTGAGCCAGAAACAAGCCCTCCATTTCCAGATCTCTCCTCTCAACTTC
  CTCCTTCAAGGAGTCTTTCTGGAAGCACTAATACTGTGTCTAGTGAAGGAGTGACAAAGGACAGCATCCC
  GTGCCTCAGTGTTAAAACACGGCCAGTACGAATGCCGCCGGGCTATCAAGCAGATCTTGTTATTCAGTTG
  GTGTGGGTAGATGGTGAGCCTCCTCAGCAAATTACCAGCCTTTCTATAAGCTCAGCATATGGAATAGTGG
  CATTTGGAAACTGCACTGGGCTGGTTGTGGTGGATTTCATACAGAAGACAGTGCTATTAAGCATGGGGAC
  CATTGACCTCTATAGATCAAGTGACCTGTACCAGCGACAGCCCCGGTCTCCTCGAAAGAACAGGCAGTTC
  ATTGCAGGCTTAACAGAGCTGAATGATAGTCCAGTTCCCCTGGAACTTGAGCGCTGCAAGTCCCCCACCT
  CAGAAACCCGAGAGAATTCCTATAATCGCTCCAGGAGCTCTAGCATCTCCAGTATTGACAAAGATTCTAA
  AGAAGCAATTACAGCTTTATACTTCATGGAATCCTTTGCACGGAAAAATGACTCTACCGTTTCCCCTTGT
  CTGTTTGTTGGAACTAGTCTGGGAATGGTAGTACTCATCTCCCTAAATCTACCATCATCAGATGAACAAA
  GGTTTACAGAGCCGGTGGTGGTATTGCCAAGTGGTACATTCCTCTCACTGAAAGGAGCAGTGCTAACATT
  TTCCTGCATGGACAGAACTGGCAGTTTAATGCAGCCTCCATACGAAGTATGGAGAGATCCAAACAACACA
  GATGAAAATGAAAAAACCTGGAAAAGGAAATTGGTCATGAACTACTCGTCTTCATCCCAAGAGATGGGAG
  ACCATCAGTATACGATAATCTGCTCAGAAAAACAAGCCAAAGTCTTCTCACTGCCTTCCCAGACCTGCCT
  TTATGTTCACAACATCACCGAGACGTCGTTCATATTGCAAGCAGATGTGGTGGTCATGTGCAACAGTGCC
  TGCCTGGCCTGCTTTTGTGCAAATGGGCATATCATGATAATGAGCTTACCTAGTCTTCGCCCAATGTTGG
  ATGTTAATTATTTGCCACTGACAGACATGAGAATAGCACGGACATTTTGTTTTACTAATGAAGGACAGGC
  ATTATACCTCGTCTCTCCCACTGAAATTCAACGGTTAACATATAGCCAAGAAATGTGTGATAATATTCAG
  GACATGTTAGGCGATTTGTTTACTCCCATAGAGACACCAGAAGCCCAAAATAGAGGCTTTCTCAAGGGAC
  TATTTGGTGGAAGTGGACAGACATTCGACAGAGAAGAACTCTTCGGGGAAGCCTCAGCAGGAAAAGCATC
  CCGAAGCCTCGCACAGCACATCCCTGGGCCAGGTAGTATAGAAGGGATGAAAGGTGCTGCTGGCGGGGTG
  ATGGGAGAGCTGACCCGAGCCCGGATTGCACTTGATGAGAGAGGGCAGCGTCTGGGCGAGCTGGAAGAGA
  AGACTGCGGGCATGATGACCAGCGCAGAAGCGTTTTCCAAGCACGCACATGAGCTAATGCTGAAGTATAA
  GGATAAGAAGTGGTACCAGTTCTAA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_001114611
• Insert Size: 3315 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001114611.1, NP_001108083.1
• RefSeq Size: 11821 bp
• RefSeq ORF: 3315 bp
• Locus ID: 207227
• UniProt ID: Q5DQR4
• Cytogenetics: 16 B3
• Gene Summary: Plays a role in vesicle trafficking and exocytosis inhibition (PubMed:25002582). In pancreatic beta-cells, inhibits insulin secretion probably by interacting with and regulating STX1A and STX4, key t-SNARE proteins involved in the fusion of insulin granules to the plasma membrane (PubMed:21998599). Plays also a role in neurotransmitter release by inhibiting basal acetylcholine release from axon terminals and by preventing synaptic fatigue upon repetitive stimulation (PubMed:24744148). Promotes as well axonal outgrowth (By similarity).[UniProtKB/Swiss-Prot Function]