Sin3b (NM_009188) Mouse Untagged Clone
SKU
MC223551
Sin3b (untagged) - Mouse transcriptional regulator, SIN3B (yeast) (Sin3b), transcript variant 1, (10ug)
$1,052.00
6 Weeks*
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
|---|---|
| Target Symbol | Sin3b |
| Synonyms | 2810430C10Rik |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data | |
| Restriction Sites | SgfI-MluI | |
| ACCN | NM_009188 |
| Insert Size | 3297 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_009188.4, NP_033214.2 |
| RefSeq Size | 4135 bp |
| RefSeq ORF | 3297 bp |
| Locus ID | 20467 |
| UniProt ID | Q62141 |
| Cytogenetics | 8 35.08 cM |
| Summary | Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription. With FOXK1, regulates cell cycle progression probably by repressing cell cycle inhibitor genes expression (PubMed:22476904).UniProtKB/Swiss-Prot Function Transcript Variant: This variant (1) represents the longer variant and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
"NM_009188" in other vectors (6)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| MG220995 | Sin3b (tGFP-tagged) - Mouse transcriptional regulator SIN3B (yeast) (Sin3b) transcript variant 1, (10ug) | 10 ug |
$1,729.00
|
|
| MR220995 | Sin3b (Myc-DDK-tagged) - Mouse transcriptional regulator, SIN3B (yeast) (Sin3b), transcript variant 1 | 10 ug |
$1,529.00
|
|
| MR220995L1 | Lenti ORF clone of Sin3b (Myc-DDK-tagged) - Mouse transcriptional regulator, SIN3B (yeast) (Sin3b), transcript variant 1 | 10 ug |
$1,829.00
|
|
| MR220995L2 | Lenti ORF clone of Sin3b (mGFP-tagged) - Mouse transcriptional regulator, SIN3B (yeast) (Sin3b), transcript variant 1 | 10 ug |
$1,829.00
|
|
| MR220995L3 | Lenti ORF clone of Sin3b (Myc-DDK-tagged) - Mouse transcriptional regulator, SIN3B (yeast) (Sin3b), transcript variant 1 | 10 ug |
$1,829.00
|
|
| MR220995L4 | Lenti ORF clone of Sin3b (mGFP-tagged) - Mouse transcriptional regulator, SIN3B (yeast) (Sin3b), transcript variant 1 | 10 ug |
$1,829.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
