Lrig1 (NM_008377) Mouse Untagged Clone

CAT#: MC223505

Lrig1 (untagged) - Mouse leucine-rich repeats and immunoglobulin-like domains 1 (Lrig1), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Lrig1
• Synonyms: D6Bwg0781e; Img; LIG-1
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC223505 representing NM_008377
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGCGCGGCCCGGTCCGGGAGTGCTCGGAGCCCCGCGCCTTGCGCCTCGCCTTCTGCTCTGGCTGCTCT
  TGCTGCTACTGCAATGGCCGGAGTCAGCGGGCGCCCAGGCTGGCCCGCGGGCCCCCTGCGCGGCCGCCTG
  CACTTGCGCCGGGGACTCGCTGGACTGCAGTGGGCGCGGGCTGGCGACGCTGCCCCGGGACCTGCCCTCC
  TGGACGCGCAGCCTAAACCTGAGTTATAACAGACTCTCCGAGATCGACTCTGCTGCTTTTGAGGACTTGA
  CGAATCTGCAGGAAGTGTACCTCAACAGCAATGAGCTGACAGCCATACCATCACTGGGCGCTGCTTCCAT
  AGGAGTTGTCTCTCTCTTTTTGCAGCACAACAAGATCCTTAGTGTGGATGGGAGCCAGCTGAAGTCGTAC
  CTGTCCTTGGAAGTGCTGGATCTGAGTTCCAACAACATCACGGAAATTCGGAGCTCCTGTTTCCCGAACG
  GCCTGCGTATAAGGGAACTCAACTTGGCGAGCAACCGCATCAGCATCCTGGAGTCTGGAGCATTTGATGG
  TCTGTCGCGGTCACTGCTGACTCTCCGTCTGAGCAAAAACAGGATCACCCAGCTTCCTGTGAAAGCGTTC
  AAGCTACCCAGGCTGACACAACTAGACCTGAATCGGAATCGGATTCGGCTGATTGAAGGCCTCACGTTCC
  AGGGGCTCGACAGCTTAGAGGTGCTGAGGCTTCAGAGGAACAACATCAGCAGGCTGACGGACGGGGCCTT
  CTGGGGGCTGTCTAAGATGCACGTGCTGCACCTGGAGTACAACAGTCTGGTGGAAGTGAACAGTGGCTCC
  CTCTATGGCCTCACAGCCCTGCACCAGCTGCACCTCAGCAACAACTCCATCTCTCGAATTCAGCGTGATG
  GCTGGAGCTTCTGCCAAAAGCTGCATGAGTTGATTCTGTCCTTCAACAACCTCACGCGGCTGGATGAGGA
  GAGTCTAGCGGAGTTGAGCAGCCTCAGTATCCTGCGCCTCAGTCACAACGCCATCAGTCACATTGCTGAA
  GGCGCCTTCAAGGGACTCAAGAGTCTGCGGGTCTTGGACCTGGACCATAACGAGATCTCGGGTACAATCG
  AGGATACCAGTGGTGCCTTTACGGGGCTTGACAACCTCAGCAAGCTGACTCTGTTTGGAAACAAGATCAA
  ATCTGTGGCTAAGAGAGCCTTCTCGGGCCTGGAAAGCCTGGAACACCTGAACCTTGGAGAGAATGCAATC
  AGGTCTGTCCAGTTTGATGCCTTTGCAAAGATGAAGAACCTTAAAGAGCTCTACATCAGCAGTGAGAGCT
  TCCTGTGTGACTGCCAGCTCAAGTGGCTGCCCCCATGGCTAATGGGTAGGATGCTGCAGGCCTTTGTGAC
  AGCCACCTGTGCCCATCCAGAGTCGCTGAAGGGCCAGAGCATTTTCTCAGTGCTGCCAGACAGCTTTGTG
  TGTGATGACTTTCCAAAGCCACAGATCATCACCCAGCCTGAGACGACCATGGCTGTGGTGGGCAAGGACA
  TCCGTTTCACATGCTCCGCAGCCAGCAGCAGCAGCTCACCAATGACCTTCGCCTGGAAGAAGGACAATGA
  GGTCCTGGCCAATGCAGACATGGAGAACTTTGCCCACGTCCGTGCACAGGACGGCGAAGTGATGGAGTAT
  ACCACTATCCTGCACCTCCGTCACGTCACCTTTGGGCACGAGGGCCGCTACCAGTGTATCATCACAAACC
  ACTTTGGCTCCACATACTCCCACAAAGCCAGGCTCACTGTGAATGTGTTGCCATCATTCACTAAAATACC
  CCATGACATTGCCATCCGGACTGGCACCACAGCCCGCCTCGAGTGTGCTGCCACGGGCCACCCTAACCCT
  CAGATTGCCTGGCAGAAGGATGGAGGCACCGATTTCCCGGCAGCTCGTGAGCGACGCATGCATGTTATGC
  CAGACGATGATGTGTTCTTCATCACTGATGTGAAAATAGACGACATGGGGGTCTACAGCTGCACTGCCCA
  GAACTCGGCAGGCTCGGTTTCAGCCAACGCTACCCTCACAGTCTTAGAAACTCCATCCTTGGCAGTGCCT
  CTGGAAGACCGTGTGGTAACTGTGGGAGAAACAGTGGCCTTCCAGTGCAAAGCAACCGGGAGCCCCACAC
  CACGCATCACCTGGCTTAAGGGAGGTCGCCCATTGAGCCTCACAGAGCGCCACCATTTCACTCCAGGCAA
  CCAGCTGCTGGTTGTTCAGAATGTGATGATAGACGATGCAGGGCGGTATACCTGTGAGATGTCTAATCCC
  CTGGGCACTGAGCGAGCACATAGCCAGCTGAGCATTTTACCTACCCCTGGCTGCCGGAAGGATGGGACCA
  CCGTAGGCATCTTCACCATTGCTGTGGTGTGCAGTATTGTCCTGACCTCGCTGGTGTGGGTGTGCATCAT
  CTACCAGACCAGGAAGAAGAGCGAGGAGTACAGCGTCACTAACACAGATGAAACCATTGTGCCTCCAGAT
  GTTCCAAGCTACCTCTCCTCTCAGGGAACCCTTTCTGACCGGCAGGAAACTGTGGTCAGGACTGAGGGTG
  GTCATCAGGCCAATGGGCACATTGAAAGCAATGGTGTGTGTCTGAGAGACCCGAGCCTCTTCCCAGAGGT
  CGACATTCATAGCACTACATGCAGGCAGCCCAAGCTGTGTGTTGGATACACTAGAGAGCCCTGGAAGGTG
  ACGGAGAAAGCCGACAGGACAGCTGCCCCACATACAACAGCACACAGTGGCTCTGCTGTATGTAGTGACT
  GCAGTACTGACACAGCCTACCATCCCCAGCCTGTGCCCAGAGACAGTGGGCAGCCAGGCACAGCGAGCAG
  CCAAGAGCTCAGGCAGCATGACCGGGAATATTCTCCACACCATCCTTACAGTGGGACTGCGGATGGGTCT
  CATACCCTCTCTGGGGGGTCCCTCTATCCAAGCAACCATGACAGAATACTGCCATCCTTGAAGAACAAGG
  CGGCGTCTGCAGATGGGAACGGAGATTCCTCTTGGACTTTAGCAAAGTTACATGAAGCAGACTGCATAGA
  CCTAAAGCCTTCTCCTACGTTAGCTTCAGGCAGCCCAGAGCTCATGGAAGACGCCATATCTACTGAAGCC
  CAGCACTTGCTTGTTTCCAATGGCCACCTCCCCAAGGCCTGTGACTCCAGCCCTGAATCTGTGCCACTGA
  AAGGGCAGATCACTGGGAAACGGAGGGGACCACTGCTATTGGCACCGAGAAGCTAG
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_008377
• Insert Size: 3276 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_008377.2, NP_032403.2
• RefSeq Size: 4966 bp
• RefSeq ORF: 3276 bp
• Locus ID: 16206
• UniProt ID: P70193
• Cytogenetics: 6 43.15 cM
• Gene Summary: Acts as a feedback negative regulator of signaling by receptor tyrosine kinases, through a mechanism that involves enhancement of receptor ubiquitination and accelerated intracellular degradation.[UniProtKB/Swiss-Prot Function]