Bmpr2 (NM_007561) Mouse Untagged Clone

CAT#: MC223313

Bmpr2 (untagged) - Mouse bone morphogenic protein receptor, type II (serine/threonine kinase) (Bmpr2), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Bmpr2
• Synonyms: 2610024H22Rik; AL117858; AW546137; BB189135; BM; BMP; BMP-; BMP-2; BMPR-2; BMPR-II; BMPRII; BRK-3; Gm20272
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC223313 representing NM_007561
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGACTTCCTCGCTGCATCGGCCCTTTCGGGTGCCCTGGCTGCTATGGGCCGTCCTGCTGGTCAGCACTA
  CGGCTGCTTCTCAGAATCAAGAACGGCTGTGTGCATTTAAAGATCCATATCAACAAGATCTTGGGATAGG
  TGAGAGTCGAATCTCTCATGAAAATGGGACAATATTATGTTCCAAAGGGAGCACGTGTTATGGTCTGTGG
  GAGAAATCAAAAGGGGACATCAATCTTGTGAAACAAGGATGTTGGTCTCACATCGGTGATCCCCAAGAGT
  GCCACTATGAAGAGTGTGTAGTAACTACCACCCCACCCTCAATTCAGAATGGAACGTACCGCTTTTGCTG
  CTGTAGTACAGATTTATGTAATGTCAACTTTACTGAGAACTTTCCACCCCCTGACACAACACCACTCAGT
  CCACCTCATTCATTTAATCGAGATGAAACGATAATCATTGCTTTGGCATCAGTTTCTGTGTTAGCTGTTT
  TGATAGTCGCCTTATGTTTTGGATACAGAATGTTGACAGGAGACCGGAAACAGGGTCTTCACAGCATGAA
  CATGATGGAGGCGGCAGCAGCAGAGCCCTCCCTTGACCTGGATAACCTGAAGCTGCTGGAGCTGATTGGA
  CGGGGTCGATACGGAGCAGTATATAAAGGTTCCTTGGATGAGCGTCCAGTTGCTGTAAAAGTATTTTCTT
  TTGCAAACCGTCAGAATTTTATAAATGAAAAAAACATTTACAGAGTGCCTTTGATGGAACATGACAACAT
  TGCTCGCTTCATAGTTGGAGACGAGAGGCTCACTGCAGACGGCCGCATGGAGTATTTGCTTGTGATGGAG
  TATTATCCCAATGGATCTCTGTGCAAATATCTGAGTCTCCACACAAGTGATTGGGTAAGCTCTTGCCGTC
  TGGCTCATTCTGTGACTAGAGGACTGGCTTATCTTCACACAGAATTACCACGAGGAGATCATTATAAACC
  CGCAATCTCCCACCGAGATTTAAACAGCAGGAATGTCCTGGTAAAGAATGACGGCGCGTGTGTTATCAGT
  GACTTTGGTTTATCCATGAGGCTAACTGGAAATCGGCTGGTGCGCCCAGGGGAAGAAGATAATGCGGCTA
  TAAGTGAGGTTGGCACAATTCGCTATATGGCACCAGAAGTGCTAGAAGGAGCTGTGAACCTGAGGGACTG
  TGAGTCAGCTCTGAAGCAAGTGGACATGTATGCGCTTGGACTCATCTACTGGGAGGTGTTTATGAGGTGT
  ACAGACCTCTTCCCAGGTGAATCTGTACCAGATTACCAGATGGCTTTTCAGACAGAAGTTGGAAACCATC
  CCACATTTGAGGATATGCAGGTTCTTGTGTCCAGAGAGAAGCAGAGACCCAAGTTCCCAGAAGCCTGGAA
  AGAAAATAGCCTGGCAGTGAGGTCACTCAAGGAAACAATTGAAGACTGCTGGGACCAGGATGCAGAGGCT
  CGGCTCACTGCACAGTGTGCTGAGGAGAGGATGGCTGAACTCATGATGATATGGGAGAGAAACAAGTCTG
  TGAGCCCAACGGTCAACCCAATGTCAACTGCTATGCAGAATGAACGCAACCTGTCACATAATAGGCGTGT
  GCCAAAAATCGGGCCTTACCCAGATTATTCCTCTTCCTCATATATTGAAGACTCTATCCATCATACTGAC
  AGCATTGTGAAGAATATTTCCTCTGAGCATTCGATGTCCAGCACACCATTGACAATAGGAGAAAAGAATC
  GAAATTCAATTAATTATGAACGACAGCAAGCACAAGCTCGAATCCCTAGCCCAGAAACAAGCGTCACAAG
  CCTGTCCACAAACACAACCACCACAAACACCACCGGCCTCACTCCAAGTACTGGCATGACCACTATATCT
  GAGATGCCATACCCAGATGAGACACATTTGCACGCCACAAATGTTGCACAGTCAATCGGGCCAACCCCTG
  TCTGCTTACAGCTGACAGAAGAAGACTTGGAGACTAATAAGCTAGATCCAAAAGAAGTTGATAAGAACCT
  CAAGGAAAGCTCTGATGAGAATCTCATGGAGCATTCTCTGAAGCAGTTCAGTGGGCCAGACCCATTGAGC
  AGTACCAGTTCTAGCTTGCTTTATCCACTCATAAAGCTCGCAGTGGAAGTGACTGGACAACAGGACTTCA
  CACAGGCTGCAAATGGGCAAGCATGTTTAATTCCTGATGTTCCACCTGCTCAGATCTATCCTCTCCCTAA
  GCAACAGAACCTTCCTAAGAGACCTACTAGTTTGCCTTTGAACACCAAAAATTCAACAAAAGAACCCCGG
  CTAAAATTTGGCAACAAGCACAAATCAAACTTGAAACAAGTAGAAACTGGAGTTGCCAAGATGAATACAA
  TCAATGCAGCAGAGCCTCATGTGGTGACAGTAACTATGAATGGTGTGGCAGGTAGAAGCCACAATGTTAA
  TTCCCATGCTGCCACAACCCAGTATGCCAATGGCGCAGTGCCAGCTGGCCAGGCAGCCAACATAGTGGCA
  CATAGGTCCCAAGAAATGCTGCAGAATCAATTTATTGGTGAGGATACCAGGCTGAATATCAATTCCAGTC
  CTGATGAGCATGAACCTTTACTGAGACGAGAGCAACAGGCTGGCCATGATGAAGGGGTTCTGGATCGTTT
  GGTAGATAGGAGGGAACGGCCATTAGAAGGTGGCCGAACAAATTCCAATAACAACAACAGCAATCCATGT
  TCAGAACAAGATATCCTTACACAAGGTGTTACAAGCACAGCTGCAGATCCTGGGCCATCAAAGCCCAGAA
  GAGCACAGAGGCCCAATTCTCTGGATCTTTCAGCCACAAATATCCTGGATGGCAGCAGTATACAGATAGG
  TGAGTCAACACAAGATGGCAAATCAGGATCAGGTGAAAAGATCAAGAGACGTGTGAAAACTCCATACTCT
  CTTAAGCGGTGGCGCCCGTCCACCTGGGTCATCTCCACCGAGCCGCTGGACTGTGAGGTCAACAACAATG
  GCAGTGACAGGGCAGTCCATTCTAAATCTAGCACTGCTGTGTACCTTGCAGAGGGAGGCACTGCCACGAC
  CACAGTGTCTAAAGATATAGGAATGAATTGTCTGTGA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_007561
• Insert Size: 3117 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_007561.3, NP_031587.1
• RefSeq Size: 11094 bp
• RefSeq ORF: 3117 bp
• Locus ID: 12168
• UniProt ID: O35607
• Cytogenetics: 1 C2
• Gene Summary: This gene encodes a serine/threonine kinase that functions as a receptor for bone morphogenetic proteins (BMPs). The encoded protein is a type II receptor that binds extracellular BMPs and forms a complex of two type II and two type I receptors at the cell membrane. This complex signals downstream to activate SMAD transcriptional regulators. This signaling is important during embryonic development. Mutations in this gene can cause pulmonary hypertension. [provided by RefSeq, Mar 2013]