Apobr (NM_138310) Mouse Untagged Clone

CAT#: MC222748

Apobr (untagged) - Mouse apolipoprotein B receptor (Apobr), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Apobr
• Synonyms: Apob-48r; Apob48r
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC222748 representing NM_138310
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGATTTTCTCCGGCTTCGTCTCCCTGGGCTACATCAGGCTTTGAGGGGAGCACTGGACTCCTTCAGTG
  CGTTTGTGTCCTACCTCGTAGGAGACACAGTCCCCACAGTAGAGAGGCAGACACAGGCAGCTGAGGAACT
  GGGAGAGGTGACTGAGGGGAAGGTTGTAGGAGAGGAAGCCCAGGAGGTACTGGAGGGACTTAGAAGTGGC
  CAGAGTGAGGGGGTAGAAGCACCCGAAGAGACTAGAAGATGCCAAGAAGGAAGTTTAGCTGGTGAACAGA
  CCTGGGGGTGGAGAGCAGATAGCTCTGCAAGGCCCCAAGCAGAAAGGCAGGACACTGGGTCCTGGAAGGC
  AGCTGAGGATGCCAGGGGCCAGGAGCCAAGTGTCCCACTGAAGCCTGAGGCAGAGCCTGGGACTCACAGA
  GACAGGAGCAGTAATACAGCCCAGGAGATCTGGGAGCACGGTGAAGAGGAAGCAAGCAGTGGGGAGCCTC
  TGAGAACCTGTGAACAGAAGGAAGAAGAGGAGGAGGTGGTCAGAGCAGCAGAGTCAGGGATGGCCGAGGG
  GGTGGAGTCACAGCCAACCTGGCACAGCGAGCCTGGGGGGAATGCTGGCACTGAGGGGCAGCATGTGACA
  GAGGACAGCAAAGAGATAGACTGGGTGGCCAAAGACATGGTTGCAGAAATCGAATGGTTTGGTGCCAAAG
  GGATTGACAAGGAAGAGGAGAGGATGGTCCCAATGAGGGATGGTGAAAGGGCAAGGGCACAGGGGACACA
  ATGCCCCGGGGCCGAGTCTGAGGACCAGGCCATGTTGAGTAGAGAGGCCTGGACAGTCTCAGACAGGGAG
  GGGGCTGATAGCCTAGGAGTTCAGGGAACAGAATACGGGTCAGACCCAGGAGACAACTTCCCAGGAACTA
  CTGGGAGAGTCTGGGTCCTAGAAGAGGCTGACAAGGGAGACCAGCAGGATGAGGTCGACGAGAAGAGAGA
  GGCTGAAGTTAGGTTTCCGATCCAGACCCTGGAGGCTGAGAGAACTGGAGAGATGACTGAAGGCCACATA
  GCTGAAGAGGAGGCTATGGGAGAACAGGAAACAGAGGGCAGCTTTGAGGATGAGGAGAGGCAAGACTTAG
  CCATCAGGGATAATGGAGTGAGTCTAGAAGAAGAGGTACGGGCAGAAGAATCCTCCAGGGAGAAAAGGAA
  CTCCTGGGCCACAGAGCCTACGCTAGTCCTAGACACGGAGGCTAAAGATGAACCTGACTGGGAAGACTCT
  CCAGAAGTCAGCACTGAGGAGTTGTTTGTGGGAGAGAGGAGTGAAGCCGCCCAGATGACACCAGAGGTAT
  TGAGAGTAAAGGTCACTGAAGGACAGGACCCTGAGCTGGTGAGACATTCCCAGGCTTTAACTAAACAACT
  TGAGGAAGGACAGAAGGGTCAGGAAGAGACTAGTGGAGCTCCAGACCTGAGCCCAGAGCGGGTGCTAAGC
  TTGAAGGAATATCCTGGGCCTGTGGGGTTTGCAGGCCCTGAGCTAGAAGCCTGGGGAAACTGGAGTAGGG
  GTGTGGACCGCAGAAATAGCCAGGAGGTAAAAGCAGATGCTGAAGCAGGCAAGGAACAGACTGCAACCGA
  GCAGGCAGTGGAGATCCGGGCTGAAGGAGGCCAGGAGGCCCAACAGCCAGAGGTCTTCGGGTCAGGAGGA
  GAGGAGGCACTGACCTCCGTAGCACTTAACCCGGAGCTGGAGGGAAGCCAAGGAGCAGAGGCGGGGACAG
  AAGAGTCAGTGGAGGAATCCAAGCCCACAGAAAACGAGGCTGCTGAGGAGGAGGCTGTAGTGCCTTGGGA
  GGCAGATGGAACTTGCAGGAAGAGGAGGCTGGAGGAGGTGACTCTGAGCCTGCAAGACAGTGAGGACACA
  GAGACCAGTTATTTGGCTGAGGAGATTATTGTGGGTATCAGGGCCGTGGATACCGAGGAAGGGCCAAAAT
  GGGAAGCTGGGTTGGCTCCAGAAACAGAGCTTGGGAAAGCCTGGTGTTCCGAGGGCAGAGGGGAGGCTGG
  GAGAGGCACGGAGCTGGAGGAGACTACAGAGAAGCAAAGTGGACAGGAAGTTGGCTTGGTGGGCTCAGCA
  GAGAAGGTGTCTGGCTATGATATCCAAGAAATTGATGGGACTGAAGAGGGGGAGCAGGCAGAGATGGAGA
  CATCTGTAATGGCAGAAGACATAAGGGGGACGGATGGTGTGACTTTAGGCTCCCAGGCAGAGAGAGCAGA
  GGGGTCCATAACCCCCATGGAGACTGAGGGGCTCCTAAGAGATCAGATGCTGTTGGAAGAAGAGGCTGGG
  GGAGGGCAGTCGCGAGAGCAGAAGGTCCACAACTCAGAGGGCGAGATCCAAACGCTGGACGACTCTTCAG
  ACCAGGAGGGGCAGCAGACACACCAAATCCCCACAGTAGCTGTGCCTGGGCCCTTGGAATCGGCTGAGGC
  CACGGCAGGTGCCCCAGGGGATGTTCACAGCAACTGGAATGAGGCCCTGCTCCCTGGGTCCCGCCTGGAT
  GTCTCTGTCCCTCGGAGTCGTGTGCTCCTCTCTCGAAGCTCCTCACGGCGGCGCTCGAGGCCCTCTTTCC
  ATCGAATCTCTGTTCCTGAGCCACAGTGTGACCCTCCCAGCCCCCAACCCCAGGCGGAGCGGCCGGTCCC
  TGAGCAATCCTCTCTTCAGCTAGAGGAAACTCCAGAGCTAAGTGCCACAAAGCCCGAGGGGACTCCAGTG
  CCAGCCAGAAGAAAAATGCTGGGGCGTGGGTTTGGCTTTGCTCATCCTGGCATGATGCAGGAGCTGCAAG
  CCCGACTGAGCCAGCCAAAGCCACAGTGA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_138310
• Insert Size: 2829 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_138310.1, NP_612183.1
• RefSeq Size: 3615 bp
• RefSeq ORF: 2829 bp
• Locus ID: 171504
• UniProt ID: Q8VBT6
• Cytogenetics: 7 F3
• Gene Summary: Macrophage receptor that binds to the apolipoprotein B48 (APOB) of dietary triglyceride (TG)-rich lipoproteins (TRL) or to a like domain of APOB in hypertriglyceridemic very low density lipoprotein (HTG-VLDL). Binds and internalizes TRL when out of the context of the macrophage. May provide essential lipids to reticuloendothelial cells. Could also be involved in foam cell formation with elevated TRL and remnant lipoprotein (RLP). Mediates the rapid high-affinity uptake of chylomicrons (CM), HTG-VLDL, and trypsinized (tryp) VLDL devoid of APOE in vitro in macrophages.[UniProtKB/Swiss-Prot Function]